Metabolism Flashcards

1
Q

MELAS

A

Complex I

Succinate dehydrogenase

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2
Q

Substrate-level phosphorylation: glycolysis

A

1,3 BPG–>3-PG [phosphoglycerate kinase]

PEP–>pyurvate [pyruvate kinase]

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3
Q

Substrate-level phosphorylation: TCA cycle

A

Succinyl CoA–>succinate [succinyl thiokinase]

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4
Q

Complex I inhibitors

A

Barbiturate
Amytal
Rotenone

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5
Q

Complex II inhibitors

A

Malonate

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6
Q

Complex III inhibitors

A

Antimycin A

Dimercarpol

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7
Q

Complex IV inhibitors

A

Cyanide
Carbon monoxide
Soidium azide
H2S

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