Metabolism Flashcards
vitamins
organic molecules in food that function as coenzymes, which combine with enzyme to allow it to function
fat soluble or water soluble
minerals
inorganic and necessary for normal metabolic functioning.
- est resting membrane potentials
- generate action potentials
- buffers, osmotic pressure
obtained from animal and plant sources
anabolism
Metabolic pathways that construct molecules, requiring energy.
- synthetic reaction
catabolism
Metabolic pathways that break down molecules, releasing energy.
- decomposition reaction
Phosphorylation
the addition of a phosphate group to a molecule
cellular metabolism
all the chemical activities of a cell
- glycolysis (make pyruvic acid; 2 ATP, 2 NADH)
- pyruvic oxidation
- Kreb cycle (make 2 ATP, 4 CO2, 6NADH, 2FADH)
- electron transport chain (34 ATP, H2O made)
Glycolysis
the breakdown of glucose by enzymes, releasing energy and pyruvic acid.
- glucose into glucose 6-P by dephoph ATP > ADP + P
- glucose 6-P becomes fructose 6-P
- become fructose 1,6-P by dephoph ATP > ADP + P
- fructose 1,6-P > dihydroxyacetone p > glyceraldehyde 3-P (x2)
- oxidize molecule by reducing NAD > NADH
- dephosp molecule by phosph ATP > ADP + P
- final product is 2 pyruvic acids
Anaerobic respiration
breakdown of glucose without oxygen
- glycolysis makes 2ATP and 2NADH
- not enough O2 so NADH joins back onto pyruvic acid molec to make lactic acid
produce: CO2, H2O, 38 ATP
- kreb cycle and electron transport chain
steps of anaerobic respiration
- glycolysis: glucose into 2 pyruvic acid , 2ATP, 2CO2
- the pyruvic acid is oxidized into Acetyl-CoA
- Acetyl-CoA and oxalocetic acid make Citric acid
- Citric acid kick starts the Krebs Cycle
- 6NADH and 2FADH from Krebs Cycle to go electron transport chain
- electron transport chain reduced O2 to make H2O and makes 36 ATP
- total: 38 ATP made
pyruvic oxidation
the transitional process in between glycolysis and the citric acid cycle in which pyruvate is oxidized into a two carbon compound (occurs in the inner mitochondrial matrix).
- now called Acetyl-CoA
-Makes 2 ATPs for each pyruvate
citric acid
a six-carbon compound formed in the Krebs cycle.
Acetyl-CoA (cc) + Oxaloacetic acid (cccc)
Krebs Cycle
produces molecules that carry energy to the second part of cellular respiration
- started by Acetyl-CoA and Oxaloacetic acid
- occurs x2 per glucose molec (as there are 2 pyruvic)
- NAD > NADH x3 (x2 in total = 6)
- FAD > FADH (x2 in total = 2)
- ADP + P > ATP (x2 in total = 2)
NADH and FADH now head off to electron transport chain
electron transport chain
- NADH and FADH from Krebs Cycle carry in e- and H+
- e- into inner compartment; H+ up protein channel into outer membrane
- carrier molecule take H+ down conc gradient, guided by ATP synthase
- as H+ down protein it spins creating enough energy to slam the P into ADP to make ATP and diffuse out
- the H+ join w O to make H2O
-makes 34 ATP for 1 glucose molecule
Biomolecules
Carbohydrates
Lipids
Proteins
Nucleic Acids
Lipid Metabolism
-triglyceride breaks into glycerol and fatty acid
- glycerol combines with glucose to make Glyceraldehyde-3-phosphate where it splits to produce Pyruvic acid
- Free fatty acids can be turned into Acetyl-CoA (enters citric acid cycle)