Metabolic Processes

Question 1

Glycolysis

Answer 1

Enzyme: Phosphofructokinase-1

Positive: AMP, Fructose-2,6-Bisphosphate
Negative: ATP, Citrate

Question 2

Gluconeogenesis

Answer 2

Enzyme: Fructose-1,6-Bisphosphatase

Negative: AMP, Fructose-2,6-Bisphosphate

Question 3

TCA Cycle

Answer 3

Enzyme: Isocitrate Dehydrogenase

Positive: ADP
Negative: ATP, NADH

Question 4

Glycogenesis

Answer 4

Enzyme: Glycogen Synthase

Positive: Glucose-6-Phosphate, Insulin, Cortisol
Negative: Epinephrine, Glucagon

Question 5

Glycogenolysis

Answer 5

Enzyme: Glycogen Phosphorylase

Positive: Epinephrine, Glucagon, AMP
Negative: Glucose-6-Phosphate, Insulin, ATP

Question 6

HMP Shunt

Answer 6

Enzyme: Glucose-6-Phosphate Dehydrogenase

Positive: NADP+
Negative: NADPH

Question 7

De Novo Pyrimidine Synthesis

Answer 7

Enzyme: Carbamoyl Phosphate Synthetase II

Positive: ATP, PRPP
Negative: UTP

Question 8

De Novo Purine Synthesis

Answer 8

Enzyme: Glutamine-Phosphoribosylpyrophosphate (PPRP) Aminotransferase

Negative: AMP, IMP, GMP

Question 9

Urea Cycle

Answer 9

Enzyme: Carbamoyl Phosphate Synthetase I

Positive: N-Acetylglutamate

Question 10

Fatty Acid Synthesis

Answer 10

Enzyme: Acetyl-CoA Carboxylase

Positive: Insulin, Citrate
Negative: Glucagon, Palmitoyl-CoA

Question 11

Fatty Acid Oxidation

Answer 11

Enzyme: Carnitine-Acyltransferase I

Negative: Malonyl-CoA

Question 12

Ketogenesis

Answer 12

Enzyme: HMG-CoA Synthase

Question 13

Cholesterol Synthesis

Answer 13

Enzyme: HMG-CoA Reductase

Positive: Insulin, Thyroxine
Negative: Glucagon, Cholesterol