Metabolic Changes Flashcards
1
Q
Factors that affect oxygen unloading
A
- temperature
- ambient PO2
- bohr effect
- BPG levels
2
Q
How does ambient PO2 affect oxygen unloading?
A
increases oxygen unloading
3
Q
How does temperature affect oxygen unloading?
A
elevated temperature promotes oxygen unloading
4
Q
How does the bohr affect oxygen unloading?
A
active tissues generate more CO2 which raises the H+ concentration and lowers the blood pH. H+ weaken the bond between hemoglobin and oxygen, promoting oxygen unloading
5
Q
How does bisphosphoglycerate (BPG) affect oxygen unloading?
A
BPG binds to hemoglobin and promotes oxygen unloading
6
Q
Define hypocapnia
A
too little CO2 in blood
7
Q
Define hypercapnia
A
too much CO2 in blood
8
Q
Define hypoventilation
A
low amount of breathing
9
Q
Define hyperventilation
A
excessive amount of breathing
