Mercury Toxicity Flashcards
Elemntal for of mercury toxicity happens through….only
Inhalation
3 forms of mercury and their MOA…
Depresses cellular enzymes
Elemental: CNS toxic
Organic: CNS toxic
Inorganic: Nephrotoxic & corrosive
Acrodynia is… & seen in….
HAAPPI ( hypertension, acute renal failure, alopecia, peeling of skin, pinm painful hands, insomnia)
Seen in inorganic toxicity found in diaper powder & tooth lotion
Cause of death in acute mercury toxicity is…
Dehydration >24hrs
RF > 10days
Treatment of acute mercury toxicity…
Gastric lavage with egg white anf skimmed milk
Mercurialism is…
Chronic mercury toxicity
Cancrum oris,mercury erithism and mercurialentis are…. and seen in…
Cancrum oris: gangrene of oral cavity
Mercury erithism: pshyco feeling shy, less confident, vague fear…
Mercurialentis: discoloration of lens
Treatment of chronic poisoning is by…
Prophylaxis with Ca, Zn, Fe
Chelation therapy
Antidotes : D-penicillamine & BAL