Mental/Psych Disorders Flashcards
Anxiety - key characteristics
- subjective sense of dread or unease
- most common psychiatric disorder
- comorbidities = depression
Anxiety - exam findings
- first step is to determine if anxiety comes before or after a medical illness or it is because of a med side effect
- evaluate for physical explanation
Anxiety - management
- Buspar (serotonin-receptor antagonist) - for patients with already established dx of anxiety, good for chronic/long-term therapy
- Benzos - very effective short-term, caution in elderly
- refer to psychiatry
Generalized Anxiety Disorder (GAD) - clinical presentation
- many potential presentations
- restless, irritability, difficulty concentrating, muscle tension, sleep disturbances, insomnia, fatigue, SOB, tachycardia, diarrhea, headache
- do thorough H&P: can cause somatic complaints, can be caused by meds
Generalized Anxiety Disorder (GAD) - diagnostics
- to rule out medical illness
- CBC, BMP, TSH, urine, EKG
Generalized Anxiety Disorder (GAD) - screening tools
- GAD-7: 7 questions about mental state over the past week. > 10 = moderate anxiety
- GAD-2
- suicide risk assessment
Generalized Anxiety Disorder (GAD) - diagnostic criteria
- *excessive anxiety and worry, occurring more days than not for at least 6 months
- anxiety/worry associated with 3 of the following: restlessness/ on-edge feeling, easily fatigued, difficulty concentrating, going blank, irritability, muscle tension, sleep disturbances
- not d/t direct effects of substance or general medical condition
- anxiety and symptoms cause significant distress in important areas of functioning
Generalized Anxiety Disorder (GAD) - non-pharm management
- education: avoid stimulants and etoh
- cognitive behavioral therapy
- most effective combo is cognitive behavioral therapy + pharm tx
Generalized Anxiety Disorder (GAD) - pharm management
- *SSRIs (first line), 4-6 weeks for effect, side effects early in tx (headaches, decreased libido), do not stop abruptly, ex: paroxetine (Paxil) and sertraline (Zoloft)
- SNRIs: venlafaxine (Effexor) CAN CAUSE INCREASED BP
- benzos: okay for short-term, may be used with SSRIs/SNRIs until they take effect
Generalized Anxiety Disorder (GAD) - follow-up/referral
- follow up: every 1-2 weeks when adjusting dose, some are on meds indefinitely
- refer to psych when provider feels they don’t have a good handle on patient
Panic Disorder - definition
- presence of recurrent, unpredictable panic attacks, which are distinct episodes of intense fear or discomfort associated with physical symptoms
Panic Disorder - diagnostic criteria
- one month of concern or worry about the attacks or change in behavior r/t them
- attacks have sudden onset (within 10 minutes) and are usually resolving over the course of an hour and occur in unexpected fashion
Panic Disorder - treatment
- goal: decrease frequency of attacks and reduce intensity
- antidepressants: SSRIs (Paxil, sertraline (Zoloft), Celexa, Lexapro
- SSRIs take a while to have effect so may need short-term benzo
Depression - types
- major depressive disorder (MDD): biggest risk factor is personal hx of depression
- dysthymic disorder: when patient has depressive symptoms for 2 years, worse in winter
- Bipolar disorders: typically worse in fall
Depression - who is more likely to be depressed?
- *previous episode of depression
- elderly
- female
- concurrent medical illness or substance abuse
Depression - when to suspect?
- Pain: headaches, chronic complaints of pain
- unexplained GI complaints
- low energy, chronic fatigue
- apathy, irritability, anxiety
- sexual complaints
Depression - physical findings
- poor hygiene, unkempt appearance
- weight gain
- significant constipation or impaction, GI complaints
- slowed body systems
Depression - in men
- thought of as “female disorder”
- more likely to talk about physical symptoms (tired, low performance/sexual desire)
- less likely to show sadness, irritability
- 4x more likely to commit suicide
Depression - screening tools
- 2-item screening tool:
1. in the past month have you felt down, depressed, or hopeless?
2. in the past month have you felt little interest or pleasure in doing things? - PHQ-9: questionnaire that helps determine if pt has mild, moderate, or severe depression
- Beck Depression Inventory
- Geriatric Depression Scale
Depression - management (non-pharm)
- psychotherapy + meds = best combo
- always rule out suicidal ideation (huge risk factor for suicide is previous attempt)
- treat underlying condition first and refer to psych if uncomfortable or too extensive
Depression - management (pharm)
SSRIs -citalopram (Celexa), paroxetine (Paxil), fluoextine (Prozac), sertraline (Zoloft) - *major side effects: headaches (usually initial but will usually fade), sexual dysfunction, serotonin syndrome SNRIs - venlafaxine (Effexor) - do not give with MAOIs - *watch BP! - usually tried when SSRIs fail TCAs - amitriptyline (Elavil) - more side effects - lethal in overdose - need cardiac monitoring MAOIs - tranylcypromine (Parnate) - dietary restriction (Tyramine) - risk of hypertensive crisis after intake of tyramine
Depression - follow-up
- 1 week: suicide risk increases (energy level increase)
- 2 weeks
- monthly
- prescription duration: 6-12 months after remission, longer if multiple disorders or longer hx of depression
Depression - referral
- suicidal or homicidal behavior
- failing therapy after 1-2 months
Major Depression - criteria
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- occurrence of one major and five or more minor symptoms for 2 weeks
- major: depressed mood or loss of interest or pleasure
- minor: depressed mood most of day, significant weight loss/gain, psychomotor agitation, insomnia, or hypersomnia
Major Depression - most common presenting symptom
- adhedonia (don’t have ability to feel pleasure)
Major Depression - treatment
- psychotherapy + SSRIs
- ECT, TMS, and ketamine infusions are also other less common options
Suicide - characteristics
- 10th leading cause of death in US
- men > women, older white, and live alone
- *70% of suicides see PCP within 6 weeks of suicide
Suicide - clinical features
- *hopelessness (reg flag)
- may or may not state intentions to you
- may start to give away possessions, quit job
- *may appear abruptly peaceful (red flag)
- self-mutilation, making threats, hallucinations/ delusions
Suicide - assessment
- always assess for suicidal ideation, intent, and plan
Suicide - risk acronym
SAD PERSONAS
S - sex A - age D - depressions P - previous attempts E - ethanol abuse R - rational thinking loss S - social support loss O - organized plan N - no spouse A - availability of lethal means S - sickness
Bipolar - characteristics
- episodic shifting between mania and major depression, hypomania, and mixed mood states
- prevention of mood cycling is crucial
- mood fluctuations are chronic and must be present for 2 years before dx can be made
Bipolar - treatment
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- Lithium (mainstay)
- side effects: GI issues, n/v, polyuria, weight gain, skin eruptions, edema
- need to be checking BMP for GFR and kidney function and lithium levels
- sustained lithium of at least 0.8 is optimal prophylaxis
- also need to be treating their depression (antidepressants)
- refer to psych if needed
Schizophrenia - characteristics
- group of syndromes characterized by “massive disruption” in thinking, mood, and behavior, poor filtering of stimuli
- often has insidious onset in late adolescence and often has poor outcome (progresses from social withdrawal, perceptual distortion, to recurrent delusions and hallucinations)
- multifactorial causes