Mental health core conditions Flashcards

1
Q

What are the symptoms of depression? 11

A
Fatigue/ loss of energy 
worthlessness
inappropriate/excessive guilt 
recurrent thoughts of death/ suicidal thoughts/attempts
diminished ability to think 
lack of concentration 
indecisiveness 
anorexia 
weight loss 
insomnia/ hypersomnia
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2
Q

What are the symptoms of atypical depression? 5

A
reactive mood 
increased appetite 
weight gain 
hypersomnia 
sensitivity to rejection
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3
Q

What are the 2 core depression questions?

A

During the last month have you been bothered by feeling down. depressed or hopeless?

Do you have little interest or pleasure in doing things

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4
Q

What are the questions to ask when assessing the risk of suicide?

A

Do you ever feel that life is hopeless and not worth living?
Do you ever think about suicide?
Have you made any plans for ending your life?
Do you have the means to do this?
what has kept you from acting on these thoughts?

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5
Q

What are the risk factors for suicide? 12

A
M>F 
<30 but also old age 
single or living alone 
prior attempts 
history of substance/ alcohol abuse 
recently started on antidepressants 
Showing signs of: hopelessness, psychosis, anxiety, agitation, severe depression 
concurrent physical illness
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6
Q

For a first episode of depression what antidepressants can you give?

A
SSRI 
Citalopram 
fluoextine 
paroxetine 
sertraline
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7
Q

Which antidepressant should you prescribe id they have co-current physical health problems?

A

sertraline as it has the lowest risk of drug interactions

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8
Q

How long after recovery should people continue taking antidepressants for?

A

at least 6 months

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9
Q

what is generalised anxiety disorder (GAD)

A

a range of anxiety disorders including acute stress disorder, OCD, panic disorder, PTSD, social phobia and specific phobias

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10
Q

Is GAD more common in M or F?

A

F

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11
Q

What are the core symptoms of GAD? 2

A

excessive anxiety and worry occurring more days than not for at least 6 months

difficulty controlling the worry or feelings of anxiety

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12
Q

What are the somatic symptoms of GAD? 7

A
restlessness
increased fatigability 
irritability 
heightened muscle tension (including chronic headache)
difficulty concentrating
sleep disturbances 
palpitations
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13
Q

What investigations can you do in GAD?

A

anxiety questionaires

GAD2 and GAD7

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14
Q

What are the questions in GAD7?

A

Over the last 2 weeks how often have you been bothered by any of the following:
Feeling nervous or on edge (GAD2)
Not being able to stop or control worrying? (GAD2)
Worrying too much over different things?
Trouble relaxing
Being so restless that it’s hard to sit still?
becoming easily annoyed or irritable?

Rank it 0-3: 3 being happens every day 0= not at all
Score 5= mild
10= moderate
15= severe

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15
Q

What are the differential diagnoses for GAD?

A

anaemia
hyperthryoidism
phaeochromocytoma
^mimic the symptoms

Panic disorders
social anxiety disorders
substance missuse
^ can co-exist

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16
Q

If CBT doesn’t help/ isn’t right what antidepressant can be offered for a first episode of GAD?

A

SSRI- sertroline

can also give SSRIs escitalopram or paroxetine

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17
Q

If symptoms of GAD don’t improve after 2 months of being on an SSRI then what do you try?

A

Another SSRI

or switch to a serotonin-noradrenaline reuptake inhibitor e.g. duloxetine, venlafaxine

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18
Q

If the person has severe anxiety which is causing them significant distress, what can you consider?

A

A short term treatment with a benzodiazepine e.g. diazepam

for no more than 2-4weeks

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19
Q

What is the advised alcohol consumption for men and for women?

A

M 4units/ day

F 3 units/ day

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20
Q

Is alcohol dependence more common in M or F?

A

M

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21
Q

What are the criteria for alcohol dependence diagnosis?

A

Strong desire/ compulsion to drink
Difficulty controlling drinking
Physiological withdrawal state when stopping drinking
Evidence of tolerance
Progressive neglect of other interests
Persistent consumption despite awareness of overtly harmful consequences

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22
Q

What are the potential incidental findings of alcohol dependence that a GP might pick up? 6

A
Abnormal blood: raised gamma-glutamyl transferase and MCV
Dilated facial capillaries 
bloodshot eyes 
hand tremor 
numerous unexplained accidents 
numerous sick notes- warning signs
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23
Q

What are the two questionnaire used to measure alcohol dependence?

A

AUDIT- alcohol use disorders identification test

SADQ- severity of alcohol dependence questionaire

24
Q

When should prophylactic oral thiamine be offered to dependent drinkers?

A

They are malnourished, or at risk of it
They have a decompensated liver
They are in acute withdrawal
Medically assisted withdrawal is planned

If really badly malnourished consider IM or IV thiamine

25
Q

What are the withdrawal symptoms? When is the onset? And how long does it normally last?

A
tremor 
nausea
vomiting 
sweating 
generalised convulsions 
Delrium tremens

3-6 hours after last drink
lasts 5-7 days

26
Q

What are delirium tremens? And what are its complications?6

A
Occur in 3% of alcohol withdrawals
rapid onset of confusion 
Complications:
seizures 
hyperthermia 
dehydration 
electrolyte imbalance 
shock 
chest infection
27
Q

Wernicke’s encephalopathy is a complication of alcohol dependence, what are its symptoms? 8 and how is it treated?

A
confusion 
ataxia
opthalmoplegia 
nystagmus 
memory disturbances 
hypothermia 
hypotension 
coma

Treat urgently with parenteral thiamine

28
Q

What ages in M and F does self harm peak at?

A

F: 15-19

M;20-24

29
Q

Is self harm more common in M or F?

A

F

30
Q

According to NICE guidelines what should happen to young people or children that have presented with self harm?

A

They should be referred to A&E and be admitted to a paediatric ward over night

31
Q

According to NICE guidelines how should over 65s who have presented with self harm be managed?

A

Referred to A&E and presumed to have suicidal thoughts until proven otherwise

32
Q

What are the risk factors for somatisation?

A

IBS and chronic pain
PTSD
antisocial personality disorder
history of sexual or physical abuse

33
Q

When does somatisation usually begin?

A

Before 30

34
Q

Is somatisation more common in M or F?

A

F

35
Q

What are the typical features of somatisation?

A

Multiple symptoms, often occurring in different organ systems
symptoms that are vague or exceed objective findings
chronic course
presence of psychiatric disorder
history of extensive diagnostic testing
rejection of previous physicians

36
Q

What are the precipitating factors for delirium? 16

A

Infection- e.g. UTI

Metabolic disturbances- e.g. hypoglycaemia, electrolytes, dehydration

CV disorder- e.g. MI

respiratory disorder- e.g. PE or COPD exacerbation

Neurological disorders- e.g. stroke, enecephalitis, SAH

Endocrine disorders- e.g. thyroid or Cushing’s

Urinary retention

GI disorders- e.g. hepatic failure, constipation, malnutrition

Severe uncontrolled pain

Depression 
sleep deprivation 
visual or hearing impairment 
emotional stress 
change in environment 

alcohol intoxication
Medication

37
Q

Which drugs precipitate delirium? 13

A
opioids
benzodiazepines 
amoldipine 
antihistamines 
anti-parkisonian meds 
tricyclic antidepressants
lithium 
antipsychotics 
anticonvulsants 
antiarrhythmics
antihypertensives
corticosteroids 
NSAIDs
38
Q

What are the risk factors for delirium? 12

A
>65 
cognitive impairment e.g. dementia 
Multiple co-morbidities 
significant injuries 
catherisation 
polypharmacy 
surgery 
alcohol excess
sensory impairment 
poor nutrition 
lack of stimulation 
terminal phase of illness
39
Q

How long do the symptoms of delirium develop over?

A

hours to days

They tend to fluctuate

40
Q

What are warning signs of delirium?

A

falling and loss of appetite

41
Q

What are the features of hyperactive delirium? 4

A

inappropriate behaviour
hallucinations
restlessness
wandering

42
Q

What are the features of hypoactive delirium? 4

A

lethargy
reduced concentration
reduced appetite
may appear quiet and withdrawn

43
Q

What are the CAM (short confusion assessment

method) criteria for delirium? 4

A

Confusion that has developed suddenly and fluctuates
Inattention
disorganised thinking
altered level of consciousness

44
Q

What investigations should be done in delirium? 14

A
urinalysis- hyperglycaemia 
sputum culture- chest infection 
FBC- infection or anaemia 
Folate and B12
Urea and electrolytes- AKI, hyponatremia/kalaemia
HbA1c
Ca 
LFTs 
ESR 
CRP
drug levels 
TFTs
CXR 
ECG
45
Q

What are the causes of dementia? 4, 12

A

Alzheimer’s (50-75%)
Vascular dementia (20%)
Dementia with Lewy bodies (5%)
Frontotemperal dementia (2%)

rarer: 
Parkinson's disease dementia 
progressive supranuclear palsy 
Huntington's 
CJD 
Normal pressure hydrocephalus 
chronic subdural haematoma 
 benign tumours 
Hypocalcaemia 
recurrent hypoglycaemia 
Vitamin B12 and thiamine def
HIV 
Syphillis
46
Q

What are the risk factors for dementia? 11

A
Age mild cognitive impairment 
Learning difficulties esp. Down's 
Genetics
CV risk factors for vascular dementia- DM, smoking, HTN 
low physical activity 
stroke 
depression 
alcohol 
low educational attainment 
low social engagement and support
47
Q

What causes young onset dementia?

A

mutation in the amyloid precursos protein (APP)

or presebillin genes: PSEN1, PSEN2

48
Q

What must a person have for a diagnosis of dementia to be made?

A

Impairment of at least 2 cognitive domains (see below) leading to significant functional decline that cannot be explained by another disorder or medication

memory
language
behaviour
visuspatial or executive function

49
Q

What are the behavioural and psychological symptoms of dementia? 8

A
agitation/ emotional labillity 
depression 
apathy 
repetitive questioning 
psychosis 
aggression 
sleep problems 
wandering
50
Q

What are the cognitive impairment problems in dementia? 5

A

memory problems

receptive or expressive dysphagia

difficulty carrying out coordinated movements e.g. dressing

Disorientation and unawareness of time and place

impairment of executive function e.g. planning or problem solving

51
Q

What are the signs of Alzheimer’s disease?

A

early impairment of episodic memory- loss of memory of recent events, repeated questioning, difficulty learning new info

52
Q

What are the signs for vascular dementia?

A

stepwise increase in severity of symptoms

focal neurological signs e.g. hemiparesis or visual field defects may be present

53
Q

what are the signs for Lewy body dementia? 7

A
repeated falls 
syncope 
severe sensitivity to antipsychotics 
delusions 
hallucinations 
Memory impairment may not be apparent in early sarges 
Parkinsonian motor features
54
Q

what are the signs for frontotemporal dementia?

A

Personality changes and behavioural disturbances e.g. apathy, sexual disinhibition
Other cognitive functions e.g. memory and perception may be preserved

55
Q

What medications are available for Alzheimer’s?

A

Acetylcholinesterase inhibitors- donepezil, galantamine and rivastigmine

Memantidine