Mental health core conditions Flashcards

1
Q

What are the symptoms of depression? 11

A
Fatigue/ loss of energy 
worthlessness
inappropriate/excessive guilt 
recurrent thoughts of death/ suicidal thoughts/attempts
diminished ability to think 
lack of concentration 
indecisiveness 
anorexia 
weight loss 
insomnia/ hypersomnia
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2
Q

What are the symptoms of atypical depression? 5

A
reactive mood 
increased appetite 
weight gain 
hypersomnia 
sensitivity to rejection
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3
Q

What are the 2 core depression questions?

A

During the last month have you been bothered by feeling down. depressed or hopeless?

Do you have little interest or pleasure in doing things

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4
Q

What are the questions to ask when assessing the risk of suicide?

A

Do you ever feel that life is hopeless and not worth living?
Do you ever think about suicide?
Have you made any plans for ending your life?
Do you have the means to do this?
what has kept you from acting on these thoughts?

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5
Q

What are the risk factors for suicide? 12

A
M>F 
<30 but also old age 
single or living alone 
prior attempts 
history of substance/ alcohol abuse 
recently started on antidepressants 
Showing signs of: hopelessness, psychosis, anxiety, agitation, severe depression 
concurrent physical illness
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6
Q

For a first episode of depression what antidepressants can you give?

A
SSRI 
Citalopram 
fluoextine 
paroxetine 
sertraline
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7
Q

Which antidepressant should you prescribe id they have co-current physical health problems?

A

sertraline as it has the lowest risk of drug interactions

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8
Q

How long after recovery should people continue taking antidepressants for?

A

at least 6 months

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9
Q

what is generalised anxiety disorder (GAD)

A

a range of anxiety disorders including acute stress disorder, OCD, panic disorder, PTSD, social phobia and specific phobias

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10
Q

Is GAD more common in M or F?

A

F

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11
Q

What are the core symptoms of GAD? 2

A

excessive anxiety and worry occurring more days than not for at least 6 months

difficulty controlling the worry or feelings of anxiety

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12
Q

What are the somatic symptoms of GAD? 7

A
restlessness
increased fatigability 
irritability 
heightened muscle tension (including chronic headache)
difficulty concentrating
sleep disturbances 
palpitations
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13
Q

What investigations can you do in GAD?

A

anxiety questionaires

GAD2 and GAD7

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14
Q

What are the questions in GAD7?

A

Over the last 2 weeks how often have you been bothered by any of the following:
Feeling nervous or on edge (GAD2)
Not being able to stop or control worrying? (GAD2)
Worrying too much over different things?
Trouble relaxing
Being so restless that it’s hard to sit still?
becoming easily annoyed or irritable?

Rank it 0-3: 3 being happens every day 0= not at all
Score 5= mild
10= moderate
15= severe

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15
Q

What are the differential diagnoses for GAD?

A

anaemia
hyperthryoidism
phaeochromocytoma
^mimic the symptoms

Panic disorders
social anxiety disorders
substance missuse
^ can co-exist

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16
Q

If CBT doesn’t help/ isn’t right what antidepressant can be offered for a first episode of GAD?

A

SSRI- sertroline

can also give SSRIs escitalopram or paroxetine

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17
Q

If symptoms of GAD don’t improve after 2 months of being on an SSRI then what do you try?

A

Another SSRI

or switch to a serotonin-noradrenaline reuptake inhibitor e.g. duloxetine, venlafaxine

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18
Q

If the person has severe anxiety which is causing them significant distress, what can you consider?

A

A short term treatment with a benzodiazepine e.g. diazepam

for no more than 2-4weeks

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19
Q

What is the advised alcohol consumption for men and for women?

A

M 4units/ day

F 3 units/ day

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20
Q

Is alcohol dependence more common in M or F?

A

M

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21
Q

What are the criteria for alcohol dependence diagnosis?

A

Strong desire/ compulsion to drink
Difficulty controlling drinking
Physiological withdrawal state when stopping drinking
Evidence of tolerance
Progressive neglect of other interests
Persistent consumption despite awareness of overtly harmful consequences

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22
Q

What are the potential incidental findings of alcohol dependence that a GP might pick up? 6

A
Abnormal blood: raised gamma-glutamyl transferase and MCV
Dilated facial capillaries 
bloodshot eyes 
hand tremor 
numerous unexplained accidents 
numerous sick notes- warning signs
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23
Q

What are the two questionnaire used to measure alcohol dependence?

A

AUDIT- alcohol use disorders identification test

SADQ- severity of alcohol dependence questionaire

24
Q

When should prophylactic oral thiamine be offered to dependent drinkers?

A

They are malnourished, or at risk of it
They have a decompensated liver
They are in acute withdrawal
Medically assisted withdrawal is planned

If really badly malnourished consider IM or IV thiamine

25
What are the withdrawal symptoms? When is the onset? And how long does it normally last?
``` tremor nausea vomiting sweating generalised convulsions Delrium tremens ``` 3-6 hours after last drink lasts 5-7 days
26
What are delirium tremens? And what are its complications?6
``` Occur in 3% of alcohol withdrawals rapid onset of confusion Complications: seizures hyperthermia dehydration electrolyte imbalance shock chest infection ```
27
Wernicke's encephalopathy is a complication of alcohol dependence, what are its symptoms? 8 and how is it treated?
``` confusion ataxia opthalmoplegia nystagmus memory disturbances hypothermia hypotension coma ``` Treat urgently with parenteral thiamine
28
What ages in M and F does self harm peak at?
F: 15-19 | M;20-24
29
Is self harm more common in M or F?
F
30
According to NICE guidelines what should happen to young people or children that have presented with self harm?
They should be referred to A&E and be admitted to a paediatric ward over night
31
According to NICE guidelines how should over 65s who have presented with self harm be managed?
Referred to A&E and presumed to have suicidal thoughts until proven otherwise
32
What are the risk factors for somatisation?
IBS and chronic pain PTSD antisocial personality disorder history of sexual or physical abuse
33
When does somatisation usually begin?
Before 30
34
Is somatisation more common in M or F?
F
35
What are the typical features of somatisation?
Multiple symptoms, often occurring in different organ systems symptoms that are vague or exceed objective findings chronic course presence of psychiatric disorder history of extensive diagnostic testing rejection of previous physicians
36
What are the precipitating factors for delirium? 16
Infection- e.g. UTI Metabolic disturbances- e.g. hypoglycaemia, electrolytes, dehydration CV disorder- e.g. MI respiratory disorder- e.g. PE or COPD exacerbation Neurological disorders- e.g. stroke, enecephalitis, SAH Endocrine disorders- e.g. thyroid or Cushing's Urinary retention GI disorders- e.g. hepatic failure, constipation, malnutrition Severe uncontrolled pain ``` Depression sleep deprivation visual or hearing impairment emotional stress change in environment ``` alcohol intoxication Medication
37
Which drugs precipitate delirium? 13
``` opioids benzodiazepines amoldipine antihistamines anti-parkisonian meds tricyclic antidepressants lithium antipsychotics anticonvulsants antiarrhythmics antihypertensives corticosteroids NSAIDs ```
38
What are the risk factors for delirium? 12
``` >65 cognitive impairment e.g. dementia Multiple co-morbidities significant injuries catherisation polypharmacy surgery alcohol excess sensory impairment poor nutrition lack of stimulation terminal phase of illness ```
39
How long do the symptoms of delirium develop over?
hours to days | They tend to fluctuate
40
What are warning signs of delirium?
falling and loss of appetite
41
What are the features of hyperactive delirium? 4
inappropriate behaviour hallucinations restlessness wandering
42
What are the features of hypoactive delirium? 4
lethargy reduced concentration reduced appetite may appear quiet and withdrawn
43
What are the CAM (short confusion assessment | method) criteria for delirium? 4
Confusion that has developed suddenly and fluctuates Inattention disorganised thinking altered level of consciousness
44
What investigations should be done in delirium? 14
``` urinalysis- hyperglycaemia sputum culture- chest infection FBC- infection or anaemia Folate and B12 Urea and electrolytes- AKI, hyponatremia/kalaemia HbA1c Ca LFTs ESR CRP drug levels TFTs CXR ECG ```
45
What are the causes of dementia? 4, 12
Alzheimer's (50-75%) Vascular dementia (20%) Dementia with Lewy bodies (5%) Frontotemperal dementia (2%) ``` rarer: Parkinson's disease dementia progressive supranuclear palsy Huntington's CJD Normal pressure hydrocephalus chronic subdural haematoma benign tumours Hypocalcaemia recurrent hypoglycaemia Vitamin B12 and thiamine def HIV Syphillis ```
46
What are the risk factors for dementia? 11
``` Age mild cognitive impairment Learning difficulties esp. Down's Genetics CV risk factors for vascular dementia- DM, smoking, HTN low physical activity stroke depression alcohol low educational attainment low social engagement and support ```
47
What causes young onset dementia?
mutation in the amyloid precursos protein (APP) | or presebillin genes: PSEN1, PSEN2
48
What must a person have for a diagnosis of dementia to be made?
Impairment of at least 2 cognitive domains (see below) leading to significant functional decline that cannot be explained by another disorder or medication memory language behaviour visuspatial or executive function
49
What are the behavioural and psychological symptoms of dementia? 8
``` agitation/ emotional labillity depression apathy repetitive questioning psychosis aggression sleep problems wandering ```
50
What are the cognitive impairment problems in dementia? 5
memory problems receptive or expressive dysphagia difficulty carrying out coordinated movements e.g. dressing Disorientation and unawareness of time and place impairment of executive function e.g. planning or problem solving
51
What are the signs of Alzheimer's disease?
early impairment of episodic memory- loss of memory of recent events, repeated questioning, difficulty learning new info
52
What are the signs for vascular dementia?
stepwise increase in severity of symptoms | focal neurological signs e.g. hemiparesis or visual field defects may be present
53
what are the signs for Lewy body dementia? 7
``` repeated falls syncope severe sensitivity to antipsychotics delusions hallucinations Memory impairment may not be apparent in early sarges Parkinsonian motor features ```
54
what are the signs for frontotemporal dementia?
Personality changes and behavioural disturbances e.g. apathy, sexual disinhibition Other cognitive functions e.g. memory and perception may be preserved
55
What medications are available for Alzheimer's?
Acetylcholinesterase inhibitors- donepezil, galantamine and rivastigmine Memantidine