mental health biology: neurons Flashcards
nerve cells that generate & transmit electrochemical impulses
neurons
contains the nucleus & is essential for life of the neuron
cell body
transmit impulses toward the cell body
dendrites
transmits impulses away from the cell body
axon
carries receptors from periphery to the CNS
afferent neurons (sensory)
carry impulses from CNS to effectors in periphery, such as muscles & glands
efferent neurons (motor)
pathways between afferent & efferent neurons
accounts for thinking, feelings, learning, language, & memory
interneurons
junction between 2 neurons
synapses
space between axon of one neuron & dendrite of another
synaptic cleft
chemical stored in neurons
electrical impulses cause a release of this
bind with receptor sites on the cell body
neurotransmitter
functions including: sleep, arousal, pain perception, modulation & coordination of movement, memory
Cholinergics: Acetylcholine
increased Acetylcholine levels
depression
decreased Acetylcholine levels
Alzheimer’s, Parkinson’s, Huntington’s
functions: mood, cognition, perception, locomotion, cardiovascular function, sleep, arousal
Monoamines: Norepinephrine
decreased Norepinephrine levels
depression
increased Norepinephrine levels
mania, anxiety, schizophrenia
functions: movement & coordination, emotions, voluntary judgement, release of prolactin
Monoamines: Dopamine
decreased Dopamine levels
Parkinson’s, depression
increased Dopamine levels
mania, schizophrenia
functions: sleep & arousal, libido, appetite, mood, aggression, pain, perception, coordination, judgement
Monoamines: Serotonin
increased Serotonin levels
anxiety
decreased Serotonin levels
depression
functions: wakefulness, pain sensation, inflammatory response
Monoamines: Histamine
decreased Histamine levels
depression
functions: interrupts progression of electrical impulses at synaptic junction
Amino Acids: Gamma-Aminobutyric Acid (GABA)
decreased GABA levels
Huntington’s, anxiety, schizophrenia, epilepsy
functions: inhibits motor neurons
Amino Acids: Glycine
toxic Glycine levels
“glycine encephalopathy”
decreased Glycine levels
spastic motor movements
functions: relays sensory information that relays sensory information & regulates reflexes
Amino Acids: Glutamate & Aspartate
decreased Glutamate & Aspartate levels
schizophrenia
increased Glutamate & Aspartate levels
Huntington’s, anxiety, depression
functions: regulation of pain
Neuropeptides: Substance P
decreased Substance P levels
Huntington’s, Alzheimer’s
increased Substance P levels
depression
functions: growth hormone inhibiting
Neuropeptides: Somatostatin
decreased Somatostatin levels
Alzheimer’s