Menstrual Abnormalities Flashcards
MCC metrorrhagia
Cervical polyps
Endometrial polyps
Normal menses Frequency Duration Volume Regularity
21-35d
4-7d
30-80ml
Monthly
AUB classification
Organic - systemic and reproductive
Dysfunctional - non/ovulatory
Endometrial biopsy indications
> 35 yo obesity hpn DM
Post menopausal women
Occurs in reproductive tears Due to local endometrial factors Simultaneous orderly tissue breakdown Spiral arteriolar constriction Midcycle rise in body temp Secretory changes
Ovulatory
Occurs in peri and postmenopause Continued estrogen w/o progesterone Unstable spontaneous haphazard breakdown Absence of vasoconstriction and BBT rise Proliferative changes
Anovulatory
Tx for hemodynamically unstable bleeding
IV estrogen
GnRH agonist and D&C
DOC for anovulatory bleeding
Progestins
Chronic ovulatory bleeding with contraception
OCP and levonorgestrol IUD +/- NSAISs and tranexamic acid
Chronic ovulatory bleeding with fertility
NSAIDs and tranexamic acid
Chronic anovulatory bleeding
With contraception
With fertility
OCP
Cyclic progestin therapy from D14-25
Used prior to surgery
Danazol androgenic steroid
Leuprolide GnRH agonist
Surgical for DUB
D&C
Endometrial ablation
Hysterectomy
Prostaglandin F2a mediated uterine ischemia
Primary dysmenorrhea
NSAIDs and OCP
MCC secondary dysmenorrhea
Endometriosis and adenomyosis