Menopause Flashcards

0
Q

Initial change signaling onset of menopause

A

Dec ovarian inhibin

Inc pituitary FSH

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1
Q

Menopause

A

12 month amenorrhea after LNMP

3 mos with FSH LH elevation

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2
Q

Fat and weight

A

Inc body weight

Gynecoid to android distribution

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3
Q

Skin and teeth

A

Collagen content dec

Teeth loss in upper jaw

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4
Q

GUT

A

Senile vaginitis (atrophy)
Urge incontinence
Uterine descent or prolapse due to dec collagen
Cysticoele rectocorle

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5
Q

Pathognomonic sign of menopause

A

Hot flush/flash

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6
Q

Long term effects

A

Inc CVD

Trabecular>cortical bone resorption

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7
Q

MC fracture in post menopausal women

A

Vertebra

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8
Q

Most accurate method to measure bone density

A

Dual Energy X ray

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9
Q

ERT

A
Dec vasomotor symptoms
Stabilize trabecula
Acidic vaginal pH
Dec dyspareunia
Inc breast cancer, heart disease, stroke, GB disease
NOT ENDOMETRIAL CA
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10
Q

CI HRT

A
Undiagnosed vaginal bleeding
Active thrombophlebitis
Chronic impaired liver function
Thromboembolic disease
Hormonally dependent ca
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11
Q

Those CI for HRT use

A

SERM

Raloxifene: agonist at bone, antagonist at uterus and breast

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