Menopause Flashcards

1
Q

Permanent cessation of menstration that occurs after the loss of ovarian activity

A

Menopause

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2
Q

When can menopause be determined?

A

1 year after last menstrual period

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3
Q

What is the median age for menopause?

A

51 years

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4
Q

What is the menopause transition known as?

A

Perimenopause

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5
Q

Estradiol and progesterone ____ during the menopause transition

A

Decrease

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6
Q

FSH _____ during the menopause transition

A

Increases

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7
Q

If a patient is having symptoms of menopause that are not “classic”, what should you order and why?

A

Prolactin to r/o hyperprolactinemia

TSH to r/o hyperthyroidism

Urine hCG

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8
Q

When do symptoms of menopause usually start?

A

about 4 years before final menses (usually age 47)

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9
Q

Should you check FSH to diagnose menopause?

A

No! Hormone levels fluctuate

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10
Q

Normal level of FSH during menopause?

A

Greater than 25

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11
Q

What proliferates the endometrium?

A

Estrogen

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12
Q

When does progesterone increase during the menstrual cycle?

A

After ovulation (Day 14)

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13
Q

When does estrogen start to decrease during the menstrual cycle?

A

After ovulation (Day 14)

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14
Q

What causes the endometrium to shed during menstruation?

A

Decreasing progesterone levels

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15
Q

What are the symptoms of menopause?

A

Vasomotor (hot flashes)
Vaginal symptoms
Sleep disturbances
New-onset depression

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16
Q

Sudden sensation of extreme heat in the upper body, particularly the face, neck, and chest

A

Vasomotor symptoms

17
Q

What characterizes vasomotor symptoms?

A

Perspiration, flushing, chills, clamminess, anxiety, heart palpitations

18
Q

What can help manage the vasomotor symptoms of menopause?

A

Administration of estrogen

19
Q

Why does the body become more sensitive to subtle changes in core body temperature?

A

Estrogen widens the regulatory zone of body temperature; less estrogen means narrower thermoregulatory zone

20
Q

What causes vaginal atrophy?

A

Hypoestrogenic state

21
Q

What are the symptoms of vaginal atrophy?

A

Vaginal or vulvar dryness
Discharge
Itching
Dyspareunia

22
Q

What increases the risk of urogenital infections in menopausal women?

A

Vaginal pH becomes more alkaline

23
Q

Data suggests that transdermal estrogen may have ____ risk of DVT compared to oral regiments

A

Lower

24
Q

If your patient has a hysterectomy and is showing vasomotor symptoms, what do you treat her with?

A

Estrogen alone

25
Q

If your patient has NOT had a hysterectomy and is showing vasomotor symptoms, what do you treat her with?

A

Estrogen AND progesterone combination (prevents endometrial hyperplasia)

26
Q

What is the precursor to endometrial cancer?

A

Endometrial hyperplasia

27
Q

How do you treat women with hormone therapy?

A

Start at the lowest dose for the shortest duration that is needed to relieve vasomotor symptoms

28
Q

How many years should HT use be limited to?

A

5 years

29
Q

What are the side effects of hormone therapy?

A

Breast tenderness
Vaginal bleeding
Bloating
Headaches

30
Q

When do you discontinue hormone therapy?

A

Individualized based on the woman