Menopause Flashcards
what are the symptoms of menopause?
hot flashes emotional lability sleep disturbance acne decreased sexual desire weight gain
what is the definition of premature ovarian failure?
menopause that occurs prior to age 40
what are risk factors for premature ovarian failure
fragile x
galctosemia
autoimmune diorders
radation
how do you treat premature ovarian failure
estrogen replacement
hormonal changes during menopause
decrease in estrogen
elevated gonadtropins: incr LH incr FSH
post menopausa ovaries and adrenal glands continue to secret androgens
transiet rise of DHEAS
what affect does menopause have to collagen?
estrogen has a positive effect on collagen therefore with menopause most of skin collagen is lost
what type of bone changes do you see during menopause?
trabecular bone loss is great than loss of cortical bone
white women especially have osteoporosis
what is osteoprosis
disorder of decreased bone density which results from increased osteoclasts activity
what is estrogens effect on osteolclast
increases their apoptosis
what is the most common fracture seen in osteoporosis?
vertebral crush fractures
how do you treat osteoporosis?
selective estrogen receptor modulators
bisphosphonates
fluoride and parathyroid hormone
calcium nd vitamind D
estrogen is protective again what cardiovascular disease?
CAD
what can you use for the treatment of hot flashes?
enlafaxine
