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Abby's Micro > Meningitis > Flashcards

Meningitis Flashcards

1
Q

Meningitis:

Causative organisms (7)

A

Neisseria meningitidis, Streptococcus pneumonia, Haemophilus influenzae, Listeria monocytogenes, Cryptococcus neoformans, Coccidioids, viruses

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2
Q

Meningitis: N. meningitidis, S. pneumoniae, H. influenzae, viruses

MoT

A

droplet

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3
Q

Meningitis: N. meningitidis

Virulence factors (3)

A

capsule, endotoxin, IgA protease

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4
Q

Meningitis: N. meningitidis

Culture/ Dx (3)

A

gram stain of CSF, rapid antigenic tests, oxidase test

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5
Q

Meningitis: N. meningitidis

Prevention (4)

A

conjugated vaccine, ciprofloxacin, rifampin, ceftriaxone

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6
Q

Meningitis: N. meningitidis

Treatment

A

penicillin G

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7
Q

Meningitis: N. meningitidis

Symptoms

A

petechiae, meningococcemia

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8
Q

Meningitis: S. pneumoniae

Virulence factors (4)

A

capsule, induction of apoptosis, hemolysin, hydrogen peroxide

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9
Q

Meningitis: S. pneumoniae

Culture/ Dx

A

gram stain of CSF

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10
Q

Meningitis: S. pneumoniae

Prevention

A

Prevnar and Pneumovax

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11
Q

Meningitis: S. pneumoniae

Treatment (3)

A

Penicillin G if sensitive; vancomycin + ceftriaxone

SERIOUS THREAT

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12
Q

Meningitis: H. influenzae

Virulence factor

A

capsule

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13
Q

Meningitis: H. influenzae

Culture/ Dx

A

culture on chocolate agar

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14
Q

Meningitis: H. influenzae

Prevention (4)

A

Hib vaccine, ciprofloxacin, rifampin, ceftriaxone

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15
Q

Meningitis: H. influenzae

Treatment

A

ceftriaxone

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16
Q

Meningitis: L. monocytogenes

MoT

A

vehicle (food)

17
Q

Meningitis: L. monocytogenes

Virulence factor

A

intracellular growth

18
Q

Meningitis: L. monocytogenes

Culture/ Dx (2)

A

Cold enrichment, rapid methods

19
Q

Meningitis: L. monocytogenes

Prevention (2)

A

cooking food, avoiding unpasteurized dairy products

20
Q

Meningitis: C. neoformans

MoT

A

vehicle (air, dust)

21
Q

Meningitis: C. neoformans

Virulence factors (2)

A

capsule, melanin production

22
Q

Meningitis: C. neoformans

Culture/ Dx (4)

A

negative staining, biochemical tests, DNA probes, cryptococcal antigen test

23
Q

Meningitis: C. neoformans

Treatment (2)

A

amphotericin B, fluconazole

24
Q

Meningitis: Coccidioids

MoT

A

vehicle (air, dust, soil)

25
Q

Meningitis: Coccidioids

Virulence factor

A

granuloma (spherule) formation

26
Q

Meningitis: Coccidioids

Culture/ Dx (2)

A

identification of spherules, Sabouraud’s agar

27
Q

Meningitis: Coccidioids

Prevention

A

avoid airborne endospores

28
Q

Meningitis: Coccidioids

Treatment

A

Amphotericin B, itraconazole

29
Q

Meningitis: Viruses

Virulence factor

A

lytic infection of host cells

30
Q

Meningitis: Viruses

Culture/ Dx (3)

A

absence of bacteria/fungi/protozoa, viral culture, antigen tests

31
Q

Meningitis: Viruses

Epidemiological features (US)

A

4/5 meningitis cases

32
Q

Meningitis:

Symptoms

A

photophobia, headache, painful/stiff neck, fever, increased WBCs in CSF

Abby's Micro (17 decks)

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