Meningitis Flashcards
0
Q
Meningitis - History
A
Fever Stiff neck Reduced consciousness Purpuric rash Sepsis features
1
Q
Meningitis - Pathogen
A
Neisseria Meningitidis
Gram -ve diplococci
2
Q
What are the features of sepsis?
A
36>temp20
HR>90
4x10^9 >WBC< 12x10^9
3
Q
Meningitis - Mechanism of infection
A
Bacteria crosses mucosal membrane so enters blood stream
Complement activation and cytokine release
Shock and DIC
4
Q
Meningitis - Management
A
Sepsis six FBC, LFT, U+Es, Glucose, Blood gases PCR of blood MCS of blood and CSF Physiological restoration
5
Q
What are the sepsis six?
A
Give oxygen Give fluids Give empirical antibiotics (ceftriaxone) Take blood Take urine Measure lactate
6
Q
Meningitis - Life threatening complications
A
AKI Irreversible hypotension Respiratory failure Raised intracranial pressure Ischaemic necrosis of digits
7
Q
Meningitis - Prevention
A
Prophylaxis
Vaccination
