Mendelian Genetics Flashcards

1
Q

What is law of segregation

A

A cell with Aa, after meiosis would be (A) and (a).

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2
Q

What is a gene

A

A code for a specific characteristic/trait

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3
Q

What is an allele

A

A version of a gene like purple or white petals

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4
Q

Dominant Allele

A

Is the trait that appears

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5
Q

Recessive allele

A

Only visible when homozygous

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6
Q

What is locus

A

Location of gene on chromosome

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7
Q

Carrier

A

They carry a copy of a recessive allele that causes a genetic disease (Hemophilia)

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8
Q

Purpose of test cross

A

Testing a heterozygous with a known homo recessive to determine if it is hetero. used to determine genotype of individual

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9
Q

Explain test cross

A

Cross Aa or AA with aa. Results will indicate genotype of female (in this case)

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10
Q

Genotype

A

combination of alleles

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11
Q

Phenotype

A

Physical trait observed

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12
Q

What is a dihybrid cross?

A

looking at two distinct traits, in total 4 genes observed

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13
Q

What is law of independent assortment

A

One gene will not affect the expression of another gene. Having blue eyes won’t affect your height

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14
Q

What is phenotypic ratio for dihybrid punett square of 2 heterozygous dihybrid cross

A

9:3:3:1

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15
Q

What is co-dmoinance

A

When you end up with a mixture of traits because you have two dominant traits

For example a roan animal, both traits would be expressed. In a cat, both black and white would be expressed

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16
Q

What is incomplete dominance

A

Where the alleles mix, red and white would make pink

17
Q

Multiple alleles

A

some genes have more ethanol two alleles, in this case you would still only inherit 2 though

18
Q

how many blood type alleles

19
Q

Alles of blood type

A

Dominant - A and B

Recessive - O

20
Q

What is a sex-linked allele

A

An allele found on a sex chromosome (Usually x because they are bigger)

21
Q

Explain the inheritance of x-linked genes

A

If an x-linked trait is recessive than it appears more in males because males only have one x chromromosome, therefore it is easier to appear in males

An example would be colourblindness which is more common in men.

22
Q

Explain y-linked traits

A

Not as common, only passed from male line

23
Q

What are barriers bodies

A

Because females have two x chromosomes, they dot want to express both genes, therefore one chromosome must be deactivated, the deactivated one becomes a Barr body

24
Q

What is a lethal allele

A

An allele that. usually causes a lethal trait, kills embryo or newborn, results in non-mendelian ratio

25
What is polygeneics
when more than one gene contributes to a trait. For example many alleles contribute to skin colour
26
What is Pleiotropy
One game can affect many traits, this is common for genetic diseases and also PKU
27
What is epistasis
One teen can mask or change the expression of another gene
28
What is a genetic disease
A disorder caused by a change in DNA
29
What is an autosomal recessive disease
Cystic fibrosis
30
What is an autosomal dominant disease
Huntington's disease
31
What are 2 sex-linked diseases
Colour blindness and hemophilia
32
Explain acute radiation syndrome
A large dose of radiation received over a short period of time can cause collapse of cardiovascular system and destruction of bone marrow
33
Explain hemophilia
X-linked recessive disease little h denotes that the individual has hemophilia