Men's Health Drugs Flashcards
Sildenafil (Viagra)
Chemical Classification
Phosphodiesterase type-5 inhibitor
Sildenafil (Viagra)
Functional Classification
Erectile agent, antihypertensive, peripheral vasodilator
Sildenafil (Viagra)
Mechanism of Action
Enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is necessary for degrading cGMP in the corpus cavernosum
Sildenafil (Viagra)
Uses
Treatment of erectile dysfunction, improvement in exercise ability, pulmonary hypertension
Sildenafil (Viagra)
Contraindications
Hypersensitivity to this product or nitrates
Sildenafil (Viagra)
Side Effects
CNS: Headache, Flushing, Dizziness, transient global amnesia, SEIZURES
CV: MI SUDDEN DEATH, CV COLLAPSE, TIAs, VENTRICULAR DYSRHYTHMIAS, CV HEMORRHAGE
MISC: Dyspepsia, Nasal Congestion, UTI, Abnormal Vision, Diarrhea, Rash, NONARTERITIC ISCHEMIC OPTIC NEUROPATHY, hearing loss, priapism, SICKLE CELL CRISIS
Sildenafil (Viagra)
Nursing Considerations
ASSESS:
- Erectile dysfunction prior to use
- Any severe loss of vision while taking this or any similar products; products should not be used
- Use of organic nitrates that should not be used with this product
- SICKLE CELL CRISIS (VASOOCCLUSIVE CRISIS): when used for pulmonary hypertension, may require hospitalization
- Cardiac status, hemodynamic parameters, exercise tolerance in pulmonary hypertension: BP, pulse