Memory and Stress uwu

Question 1

How is memory reinforced

- gimme key location in brain

Answer 1

Hippocampus @ Temporal Lobe

• connects w Limbic system for emotions
• enhanced w environmental connection; strong pathway repeated flowing of info;

Question 2

Gimme the 3 types of memory and subset of LTM

Answer 2

Sensory Memory
STM
LTM
- explicit
-- semantic, episodic - need conscious effort to remember
- implicit

Question 3

HSV attack on brain
- pathology, gross and histology

HSV vs HPC CPE

Answer 3

Temporal Lobe, hippocampus
Gross: Brain, temporal lobe atrophy
Histology: Cowdry bodies

HSV: multinucleated, nuclear inclusions
HPV: Enlarged nuclei, perinuclear halo, wrinkled nuclei

Question 4

Stress

• gimme hormone axis
• gimme where in the brain does this affect

Answer 4

Hypothalamus
- Corticotropin Releasing Factor

Anterior Pituitary
- Adrenal Corticotropic Hormone

Adrenal
- Cortisol

Amygdala is for stress response, anxiety
- right in front of hippo
Hippocampus for memory, emotion;
- chronic cortisol affects memory

Question 5

Chronic Stress side effects

- link to Depression?

Answer 5

Memory
IHD, depression

• Decreases Brain Derived Neurotrophic Factor
• • neuron death
• depression decrease BDNF
• but if treated w antidepressants
• increases BNDF, increase Serotonin, NE neurons; in hippocampus;