membranes Flashcards

1
Q

components of membrane?

A

plb
proteins (integral, peripheral, membrane anchored)
glycolipids and glycoproteins (signalling)
cholesterol

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2
Q

purposes of membrane proteins?

A

transport
signalling
enzymes
joining cells to each other and to the ECM

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3
Q

4 ways in which membrane protein activity is regulated?

A

ligand gated: ligand needs to bind to protein receptor to activate it
voltage gated: protein active when voltage drop across membrane is above threshold level
energy dependent: protein operates when sufficient ATP is available
physical stretching

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4
Q

4 examples of active transport?

A

electrogenic pumps
Na+/K+ pumps
sucrose-H+ transprot system
ATP synthase pump

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5
Q

describe electrogenic pumps

A
  • plants fungi bacteria

- actively transport H+ ions out of cell to make conc and voltage gradient

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6
Q

describe Na+/K+ pump

A
antiport pump
Na+ binds to protein
ATP breaks down, Pi attaches to protein
protein changes shape
Na+ goes out of cell
K+ binds to protein
Pi released
protein changes shape
K+ goes into cell
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7
Q

describe sucrose-H+ transport system

A

active transport pump transports H+ out of cell
H+-sucrose cotransporter lets H+ flow down conc gradient, creating energy for sucrose to go into cell against conc gradient

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8
Q

describe ATP synthase pump

A

H+ transproted to intermembrane space, breaking down NADH

H+ flows back down along conc gradient which enables synthesis of ATP

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9
Q

classes of pumps?

A

uniport (one particle)
symport (2 particles in same direction)
antiport (2 particles in opposite direction)

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