membranes Flashcards
components of membrane?
plb
proteins (integral, peripheral, membrane anchored)
glycolipids and glycoproteins (signalling)
cholesterol
purposes of membrane proteins?
transport
signalling
enzymes
joining cells to each other and to the ECM
4 ways in which membrane protein activity is regulated?
ligand gated: ligand needs to bind to protein receptor to activate it
voltage gated: protein active when voltage drop across membrane is above threshold level
energy dependent: protein operates when sufficient ATP is available
physical stretching
4 examples of active transport?
electrogenic pumps
Na+/K+ pumps
sucrose-H+ transprot system
ATP synthase pump
describe electrogenic pumps
- plants fungi bacteria
- actively transport H+ ions out of cell to make conc and voltage gradient
describe Na+/K+ pump
antiport pump Na+ binds to protein ATP breaks down, Pi attaches to protein protein changes shape Na+ goes out of cell K+ binds to protein Pi released protein changes shape K+ goes into cell
describe sucrose-H+ transport system
active transport pump transports H+ out of cell
H+-sucrose cotransporter lets H+ flow down conc gradient, creating energy for sucrose to go into cell against conc gradient
describe ATP synthase pump
H+ transproted to intermembrane space, breaking down NADH
H+ flows back down along conc gradient which enables synthesis of ATP
classes of pumps?
uniport (one particle)
symport (2 particles in same direction)
antiport (2 particles in opposite direction)