Membrane Structure Flashcards
Function of plasma membrane
- Encloses the cell
- Define its boundaries
- Maintains essential differences between cytosol and extra ellipse environment.
- Contains proteins that acts as a sensors of external signals.
Used to synthesize ATP, to drive transmembrane movement of selected salutes, to product electrical signals
Ion gradients
Thickness of cell membrane
5 nm
Dissolve readily in water
Hydrophilic molecules
Insoluble in water
Hydrophobic molecules
Two ways of how lipid molecules aggregate
- Spherical micelles
2. Bilayers
Bonds that produce kinks
Cis double bonds
Composition of lipid bilayer
- Phospholipids
- Cholesterol
- Glycolipids
Major phospholipids in plasma membrane of mammalian cell
Phosphatidylcholine
Phosphatidylethanolamine
Phosphatidylserine
Sphingomyeline
polypeptide that only crosses once
Single pass membrane proteins
The polypeptide chain crosses multiple times
Multi-pass transmembrane proteins
Polysaccharide chains of integral membrane
Proteoglycan
Carbohydrate rich zone on the cell surface. Cell coat
Glycocalyx
Have long attracted fatty hydrocarbon chains, holds adjacent molecules together transiently in small microdomains
Sphingolipid
Transient phase separations in the fluid lipid bilayer where sphingolipids become concentrated
Microdomains