Membrane Potential Flashcards
Most cells have a negative resting membrane potential
True (usually between -30 and -50)
Electrical gradient, think of one thing:
Opposites attract
Like charges repel
Ionic Gradient consists of 2 things:
2 gradients:
Chemical and Electrical
Vm
Membrane potential is difference in electrical potential between the INSIDE of the cell and the OUTSIDE
Depolarization
Less polarizing (moving more towards 0)
Ionic Equilibrium
Balance between chemical and charge
Ionic gradient/equilibrium
A gradient resulting from combination of the electrical and concentration gradients acting on a specific ion. An ionic equilibrium occurs when the combined forces are balanced, although neither on its own may appear to be in balance
To make an ionic gradient
Need:
Selective cell membrane
Na/K ATPase
Permeability of the ions (by definition has charge)
Na+: Low at rest
Ca2+: low
K+: Higher at rest (100x that of Na+)
Cl-: moderate
Amino acids (proteins) in the cell have a NEGATIVE charge OVERALL
True
Thus gives cell a negative charge inside and thus a negative membrane potential
Na/K ATPase pump
3 Na+ OUT
2 K+ IN
Both are moving against their gradients