Meiosis Flashcards

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1
Q

What is the goal of Meiosis?

A

Goal: begin with a normal cell (2 copies of each chromosome) and end with a cell that has half the genetic content (1 copy of each chromosome) and is genetically unique.

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2
Q

Mitosis

A

Mitosis—new daughter cells are generated.
Produces identical cells
DNA is doubled during the process, and then divided to an identical amount.
For growth and replacement.

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3
Q

Meiosis

A

Meiosis–gametes are generated for sexual reproduction.
Produces cells that differ genetically.
Hereditary information reduced by one half.
For producing reproductive cells (gametes).
reduction division
division that halves the chromosome number
a diploid cell (in an ovary or testes) divides to produce haploid cells, gametes

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4
Q

How many chromosomes does a haploid have?

A

23 chromosomes for humans
(1n = 23 for humans)
possessing a single version of each chromosome type

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5
Q

How many chromosomes does a Diploid have?

A

46 chromosomes for humans
(2n = 46 for humans)
possessing two versions of each chromosome type

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6
Q

Which of the following statements about homologous chromosomes is incorrect?
A. Each chromosome has the same genes in the same order (X and Y is the exception)
B. One is inherited from the male parent and the other from the female
C. Each consists of two sister chromatids after the S phase of mitosis
D. Are the same in terms of DNA nucleotide composition

A

D. Are the same in terms of DNA nucleotide composition

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7
Q

Define gametes

A

Produced by special cells in ovaries and testes
sex cells such as eggs and sperm.
haploid, 1n chromosomes (one of each chromosome), ½ the amount of DNA
formed by meiosis

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8
Q

Define somatic cells

A

All other body cells in an organism
diploid in most, 2n chromosomes (two of each chromosome), full amount of DNA
formed by mitosis

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9
Q

Define Allele

A

Versions of a gene coding for a particular protein

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10
Q

Understand the term tetrad

A

Tetrad: a pair of homologous, duplicated chromosomes

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11
Q

How many sister chromatids are there in a tetrad?

A

4

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12
Q

What is crossing over?

A

The chromosomes exchange pieces of themselves to the other chromosome from the paternal and maternal chromosomes
This is the

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13
Q

Consequences of crossing over

A

Crossing over in the first phase of meiosis
At least one cross over in all 23 pair (several in the larger chromsomes)
Nearly infinite variation possible for the gametes produced

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14
Q

Consequences of Independent assortment

A

Independent assortment in the first phase of meiosis
each tetrad moves to the metaphase I plate independently of the other tetrads
the total number of possible outcomes = 2n (n = number of haploid chromosomes)
2^23 for humans, 8.4 million different ways (different gametes)

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15
Q

Explain why meiosis is called “reduction division,” and why it is necessary for gamete formation.

A

formation of gametes that are going to join in fertilization requires a reduction of the genetic material to ½
besides crossing over and independent assortment, meiosis reduces the number of chromosomes from 2 of each type to 1 of each type (2n to 1n, diploid to haploid)
otherwise, every generation would double the amount of homologous genetic information

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16
Q

Explain why meiosis is called “reduction division,” and why it is necessary for gamete formation.

A

formation of gametes that are going to join in fertilization requires a reduction of the genetic material to ½
besides crossing over and independent assortment, meiosis reduces the number of chromosomes from 2 of each type to 1 of each type (2n to 1n, diploid to haploid)
otherwise, every generation would double the amount of homologous genetic information

17
Q

Explain why meiosis is called “reduction division,” and why it is necessary for gamete formation.

A

formation of gametes that are going to join in fertilization requires a reduction of the genetic material to ½
besides crossing over and independent assortment, meiosis reduces the number of chromosomes from 2 of each type to 1 of each type (2n to 1n, diploid to haploid)
otherwise, every generation would double the amount of homologous genetic information

18
Q

Explain why meiosis is called “reduction division,” and why it is necessary for gamete formation.

A

formation of gametes that are going to join in fertilization requires a reduction of the genetic material to ½
besides crossing over and independent assortment, meiosis reduces the number of chromosomes from 2 of each type to 1 of each type (2n to 1n, diploid to haploid)
otherwise, every generation would double the amount of homologous genetic information

19
Q

Explain why meiosis is called “reduction division,” and why it is necessary for gamete formation.

A

formation of gametes that are going to join in fertilization requires a reduction of the genetic material to ½
besides crossing over and independent assortment, meiosis reduces the number of chromosomes from 2 of each type to 1 of each type (2n to 1n, diploid to haploid)
otherwise, every generation would double the amount of homologous genetic information

20
Q

In meiosis in males, the X and Y chromosomes are mostly not homologous (don’t have the same genes) so there is essentially no crossing over between the X and Y
T/F

A

True

21
Q

How can XY individuals can be phenotypically female?

A

Suppose one of the genes that determines “maleness” on the Y chromosome is defective

22
Q

What is Androgen Insensitivity Syndrome?

A

Known as Intersex
A person is a female but has an XY chromosome
As a result, estrogen (chemical messenger confers a female phenotype) is not converted into testosterone (confers a male phenotype)
Then by default, a person who is genetically a male will develop phenotypically into a female
Occurs in 1 of 13,000 - 65,000 Births

23
Q

How can a person can have an odd number of chromosomes (47)?

A

Because an egg may have two of a certain chromosome in the egg then it is fertilized which means there is a third chromosome.
Normally only Trisomy 21 (Down’s syndrome) is the only case that will not result in the death of the baby before birth

24
Q

What is Klinefelter’s syndrome?

A

Additional X chromosome
XXY so they have 47 chromosomes
They are men who have some female qualities
Can be treated by receiving injections of male testosterone