Meiosis Flashcards

1
Q

How does genetic variation in gametes arise?

A

It arises from the independent assortment of chromosomes, crossing over, and random fertilization.

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2
Q

How does meiosis affect the number of chromosomes from parent to daughter cells?

A

Meiosis reduces the number of chromosome sets from diploid to haploid.

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3
Q

What is the role of gametes in plants and animals that reproduce sexually?

A

Reproductive cells called gametes are the vehicles that transmit genes from one generation to the next.

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4
Q

How do fertilization and meiosis cause unique offspring?

A

During fertilization, male and female gametes unite, passing genes from both parents to their offspring. Because genes are inherited from two parents, the offspring has a unique combination. This uniqueness is in large part due to meiosis followed by fertilization.

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5
Q

Are gametes diploid or haploid?

A

Haploid.

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6
Q

What is a karyotype?

A

A display of the chromosome pairs of a cell, arranged by size and shape.

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7
Q

Describe the characteristics of the human karyotype.

A

There are 46 chromosomes: 2 chromosomes of each of 23 types. The homologous chromosomes have the same length, centromere position, and gene arrangement.

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8
Q

What are autosomes?

A

The autosomes are the non-sex chromosomes (1-22).

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9
Q

What are homologous chromosomes?

A

A couple of homologous chromosomes are a set of one maternal and one paternal chromosome that pair up with each other inside a cell during fertilization. They have the same length, centromere position, and gene location (though the genes are not identical).

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10
Q

How do somatic cells reproduce?

A

In humans, somatic cells (2n) divide by mitosis and contain 23 pairs of chromosomes (46 in total)–a maternal set and a paternal set–and are diploid (2n).

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11
Q

How do germ cells reproduce?

A

In humans, germ cells (2n) divide by meiosis and result in gametes that contain a single set of chromosomes: gametes are haploid (n).

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12
Q

How does a zygote divide?

A

Through mitosis.

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13
Q

What are sister chromatids?

A

A sister chromatid refers to the identical copies formed by the DNA replication of a chromosome, with both copies joined together by a common centromere. In other words, a sister chromatid may also be said to be ‘one-half’ of the duplicated chromosome.

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14
Q

What is the difference between sister chromatids and non-sister chromatids?

A

Sister chromatids are the duplicated chromosome themselves, and they contain the exact same alleles. Non-sister chromatids are the chromatids of the homologous chromosome, and they may contain different alleles.

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15
Q

What happens in interphase?

A

In interphase (S phase), chromosomes duplicate, yielding sister chromatids.

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16
Q

What happens in prophase I?

A

The centrosomes move, the spindle forms, duplicated chromosomes pair, and crossing over happens.

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17
Q

What happens in metaphase I?

A

Pairs of homologous chromosomes attach to the metaphase plate. Independent assortment happens here.

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18
Q

What happens in anaphase I?

A

Homologous chromosomes separate and move toward opposite poles–the sister chromatids remain paired.

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19
Q

What happens in telophase I and cytokinesis?

A

The cytoplasm divides, and the cleavage furrow forms–each chromosome consists of two sister chromatids.

20
Q

What is the overall goal of meiosis I?

A

To separate homologous chromosomes.

21
Q

What is crossing over?

A

Crossing over is a mechanism by which you can add additional genetic variation because the chromosome from mom and the chromosome from dad are swapping information.

22
Q

What is independent assortment?

A

Independent assortment is the process where the chromosomes move randomly to separate poles during meiosis. A gamete will end up with 23 chromosomes after meiosis, but independent assortment means that each gamete will have 1 of many different combinations of chromosomes.

23
Q

In which phase of meiosis does the cell go from diploid to haploid?

A

Teleophase I/cytokinesis.

24
Q

Which processes in meiosis introduce genetic variation?

A

Crossing over and independent assortment.

25
What happens in prophase II?
The spindle forms.
26
What happens in metaphase II?
Chromosomes attach to the metaphase plate; because crossing over happened, the two sister chromatids are not identical.
27
What happens in anaphase II?
Sister chromatids separate and move toward opposite poles.
28
What happens in telophase II/cytokinesis?
Nuclei form, the chromosomes begin to decondense, cytokinesis occurs, and the cleavage furrow forms.
29
Why are the sister chromatids not identical in metaphase II?
Crossing over made them non-identical.
30
Why does crossing over happen?
Crossing over during prophase I produces recombinant chromosomes: individual chromosomes that carry DNA derived from two parents.
31
What is a chiasma?
A chiasma is the point of contact, the physical link, between two chromatids belonging to homologous chromosomes. At a given chiasma, an exchange of genetic material can occur between both chromatids.
32
In which phase does the breakdown of proteins holding sister chromatid arms together occur?
Anaphase I.
33
What would the result be if crossing over did not occur?
If crossing over did not occur, when you separate the sister chromatids, they would be identical. Therefore, two of the haploid cells would be the same, and two wouldn't
34
What holds sister chromatids together?
Cohesins.
35
What is the role of the synaptonemal complex?
It holds the homologs together, stabilizing them and allowing for chiasma formation and crossover. This alignment is called synapsis.
36
How do enzymes play a role in crossing over?
Enzymes come in and break the DNA at a specific point in both sister chromatids. Because the cell wants to repair that point, parts from each chromatid cross over.
37
How is the number of possible combinations for the assortment of chromosomes related to the diploid number of the organism?
The number of possible combinations increases with the diploid number of the organism and equals 2^n, where n is the haploid number. For humans, this is 2^23 (8.4 million possibilities).
38
Determine if the event occurs in mitosis or meiosis: crossing over.
Meiosis
39
Determine if the event occurs in mitosis or meiosis: homologous chromosomes pair at the metaphase plate.
Meiosis
40
Determine if the event occurs in mitosis or meiosis: the production of diploid cells.
Mitosis
41
Determine if the event occurs in mitosis or meiosis: the production of genetically identical cells.
Mitosis
42
Determine if the event occurs in mitosis or meiosis: homologs separate.
Meiosis
43
What does it mean when a fruit is parthenocarpic?
It means the fruit can develop without fertilization. The fruit is seedless, and propagation is via side shoots.
44
What is the problem with commercial bananas?
The Cavendish strain is parthenocarpic, meaning that every plant is a clone; there is no genetic variation. The fungus "Tropical Race 4" is threatening the Cavendish with extinction.
45
What does it mean to be triploid?
Two sets of chromosomes come from one original parent and one set from the other.
46
Why don't bananas form gametes?
Because they are triploid, homologous chromosomes cannot pair properly during metaphase I, and meiosis fails. So, no gametes are formed.