Mehl. antipsychotic drugs 04-06 (1) Flashcards
Anti-psychotic meds. categorized?
Categorized as typical (antagonize D2 receptors) or atypical (antagonize mostly D2 receptors, but also have additional binding effects at other receptors such as D4 or serotonin).
Anti-psychotic meds. Typical, mechanism?
typical (antagonize D2 receptors)
Anti-psychotic meds. Atypical, mechanism?
Atypical (antagonize mostly D2 receptors, but also have additional binding effects at other receptors such as D4 or serotonin).
(antagonize D2 receptors)?
typical
(antagonize mostly D2 receptors, but also have additional binding effects at other receptors such as D4 or serotonin).?
atypical
HY typicals?
HY Typicals: Haloperidol, Chlorpromazine, Prochlorperazine, Thioridazine.
Haloperidol?
HY Typical
Chlorpromazine?
HY Typical
Prochlorperazine?
HY Typical
Thioridazine?
HY Typical
HY Atypicals: Old Closets Quietly Whisper (Risper) from A to Z. abbreviation.
HY Atypicals: Olanzapine, Clozapine, Quetiapine, Risperidone, Aripiprazole, Ziprasidone
Olanzapine?
HY Atypical
Clozapine?
HY Atypical
Quetiapine?
HY Atypical
Risperidone?
HY Atypical
Aripiprazole?
HY Atypical
Ziprasidone?
HY Atypical
All anti-psychotics can cause extra-pyramidal side-effects (EPS), anti-cholinergic side-effects, neuroleptic malignant syndrome (NMS), QT prolongation, and hyperprolactinemia (D2 agonism normally inhibits prolactin).
.
why atypical more preferred?
Typicals are older and more known for causing these effects.
As a result, atypicals are usually the preferred first-line agents for schizophrenia and psychotic disorders.
atypicals first-line agents for ….?
schizophrenia and psychotic disorders.
Typicals like haloperidol are still occasionally used acutely for??
violent delirium, Tourette, or psychosis patients who have poor medication compliance.
A 2CK form wants haloperidol decanoate as the answer for what’s good to use for schizophrenia patient with poor compliance.
.
Prochlorperazine can be used as ….????
an anti-nausea medication despite being a typical anti-psychotic.
Clozapine exceedingly HY about clozapine????
Clozapine can cause neutropenia (agranulocytosis). !!!!!
Olanzapine and clozapine can worsen ….
obesity
Aripiprazole or ziprasidone are better for…?
high-BMI patients.
…… can cause Corneal deposits.
Chlorpromazine
….. can cause reTinal deposits.
Thioridazine