Mehl. antipsychotic drugs 04-06 (1) Flashcards

1
Q

Anti-psychotic meds. categorized?

A

Categorized as typical (antagonize D2 receptors) or atypical (antagonize mostly D2 receptors, but also have additional binding effects at other receptors such as D4 or serotonin).

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2
Q

Anti-psychotic meds. Typical, mechanism?

A

typical (antagonize D2 receptors)

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3
Q

Anti-psychotic meds. Atypical, mechanism?

A

Atypical (antagonize mostly D2 receptors, but also have additional binding effects at other receptors such as D4 or serotonin).

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4
Q

(antagonize D2 receptors)?

A

typical

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5
Q

(antagonize mostly D2 receptors, but also have additional binding effects at other receptors such as D4 or serotonin).?

A

atypical

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6
Q

HY typicals?

A

HY Typicals: Haloperidol, Chlorpromazine, Prochlorperazine, Thioridazine.

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7
Q

Haloperidol?

A

HY Typical

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8
Q

Chlorpromazine?

A

HY Typical

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9
Q

Prochlorperazine?

A

HY Typical

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10
Q

Thioridazine?

A

HY Typical

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11
Q

HY Atypicals: Old Closets Quietly Whisper (Risper) from A to Z. abbreviation.

A

HY Atypicals: Olanzapine, Clozapine, Quetiapine, Risperidone, Aripiprazole, Ziprasidone

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12
Q

Olanzapine?

A

HY Atypical

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13
Q

Clozapine?

A

HY Atypical

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14
Q

Quetiapine?

A

HY Atypical

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15
Q

Risperidone?

A

HY Atypical

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16
Q

Aripiprazole?

A

HY Atypical

17
Q

Ziprasidone?

A

HY Atypical

18
Q

All anti-psychotics can cause extra-pyramidal side-effects (EPS), anti-cholinergic side-effects, neuroleptic malignant syndrome (NMS), QT prolongation, and hyperprolactinemia (D2 agonism normally inhibits prolactin).

19
Q

why atypical more preferred?

A

Typicals are older and more known for causing these effects.

As a result, atypicals are usually the preferred first-line agents for schizophrenia and psychotic disorders.

20
Q

atypicals first-line agents for ….?

A

schizophrenia and psychotic disorders.

21
Q

Typicals like haloperidol are still occasionally used acutely for??

A

violent delirium, Tourette, or psychosis patients who have poor medication compliance.

22
Q

A 2CK form wants haloperidol decanoate as the answer for what’s good to use for schizophrenia patient with poor compliance.

23
Q

Prochlorperazine can be used as ….????

A

an anti-nausea medication despite being a typical anti-psychotic.

24
Q

Clozapine exceedingly HY about clozapine????

A

Clozapine can cause neutropenia (agranulocytosis). !!!!!

25
Q

Olanzapine and clozapine can worsen ….

26
Q

Aripiprazole or ziprasidone are better for…?

A

high-BMI patients.

27
Q

…… can cause Corneal deposits.

A

Chlorpromazine

28
Q

….. can cause reTinal deposits.

A

Thioridazine