meglidinele(reprezentantii prandiali ai glicemiei) Flashcards

1
Q

reprezentanti meglidine

A

repaglinida
nateglinida

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

denumire comerciala repaglinida

A

novonorm 0,5 sau 1,2 mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

denumire comerciala nateglinida

A

starlix 120mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

mecanism de actiune

A

inchiderea canalului de K-ATP in celule beta cu o durata mai mica de 3 ore
au fost concepute pentru a restabili eliberarea de insulinain faza de post prandiala precoce, fara stimulare prelungita in perioada ulterioara de post

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

indicatii

A

mai ales unde avem valori postprandiale crescute ( o masa= o doza)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

mod de administrare

A

se pot asocia cu biguanidele, eventual insulina bazala
initiere doza minima
titrare la 10-14 zile
inaintea meselor principale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

efecte adverse

A

hipoglicemie
crestere in greutate
greturi
constipatie
diaree

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

contra indicatii

A

dz1
cetoacidoza
I.H.
hipersensibilitate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly