inhibitorii de dpp-4 Flashcards
1
Q
reprezentanti dpp-4
A
sitagliptina
saxagliptina
vildagliptina
2
Q
denumire comerciala sitagliptina
A
januvia
3
Q
denumire comerciala saxagliptina
A
onglyza 5mg 1cap/zi
4
Q
denumire comerciala vildagliptina
A
galvos 50mg 2 cap/zi
5
Q
mecanism
A
inhiba enzima dpp-4
impiedica inactivarea rapida a GLP-1
care la randul sau creste secretia de insulina si scade pe cea de glucagon
6
Q
indicatii
A
dz2 necontrolat cu metformin sau sulfonilureice
IR
7
Q
efecte adverse
A
favorizeaza cresterea in greutate
tulburari digestive
cefalee
anafilaxie
edem angioglotic
afectiuni cutanate exfoliative
8
Q
contraindicatii
A
dz1
cetoacidoza
sarcina
alaptare
