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Abog oral boards > Meds- OB > Flashcards

Meds- OB Flashcards

1
Q

Ampicillin
Indication
Dose
MOA
SI/CI

A

2g then 1g q4h IV
GBS ppx- inhibits cell wall synthesis
Allergy

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2
Q

Rhogam
Indication
Dose
MOA
Side effects/CI

A

Rh neg
300 mcg IM
clears anti-D coated red cells
allergy

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3
Q

Betamethasone
Indication
Dose
MOA
Side effects/CI

A

antenatal steroids
12mg IM q24h x 2 doses
accelerates pneumocyte development
Allergy

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4
Q

Magnesium sulfate neuroprotection
Indication
Dose
MOA
Side effects/CI

A

6g bolus, then 2g IV/hr
stabilizes cerebral blood flow, reduces CP
Flushing, NV

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5
Q

Magnesium seizure ppx/ eclampsia
Indication
Indication
Dose
MOA
Side effects/CI

A

4g bolus then 2g/hr IV
4-6g bolus for eclampsia
increases seizure threshold, vasodilation
toxicity, renal disease

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6
Q

PPROM latency abx
Indication
Dose
MOA
Side effects/CI

A

ampicillin 2g q6h x 48h IV, then amox 250 mg q8h x5d PO
azithromycin 1g po x1
GBS, gram neg, anerobes, CT/ureaplasma
allergy

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7
Q

labetalol
Indication
Dose
MOA
Side effects/CI

A

antihypertensive
20, 40 80 mg IV q10h
beta blocker
asthma, bradycardia
max dose IV is 300 mg

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8
Q

Nifedipine
Indication
Dose
MOA
Side effects/CI

A

10-20 mg PO q20 min
antihypertensive
calcium channel blocker
tachycardia,headache
max daily dose is 180 mg

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9
Q

hydralazine
Indication
Dose
MOA
Side effects/CI

A

anti hypertensive
5, 10 mg IV q 20 min
max daily dose is 20 mg IV
arterial vasodilator
headache

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10
Q

aspirin
Indication
Dose
MOA
Side effects/CI

A

preeclampsia prevention
81 mg PO
decreases thromboxane production (thromboxane promotes vasoconstriction and platelet aggregation)
allergy, high risk for bronchospasm (nasal polyps or asthma), hx of GI bleeding or PUD

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11
Q

ursodeoxycholic acid
Indication
Dose
MOA
Side effects/CI

A

cholestasis
300 mg PO TID
decreases cholesterol content of bile
allergy

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12
Q

oxytocin
Indication
Dose
MOA
Side effects/CI

A

IOL , uterotonics
2mu/min IV
activates receptors to stimulate contractions (elevated intracellular calcium)
Hypotension/Na, tachysystole

for PPH
40 u in 1L, increases uterine contractility, hypotension, CV collapse

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13
Q

misoprostol
Indication
Dose
MOA
Side effects/CI

A

IOL, uterotonic
25 mcg q3-6h PV
PGE1 analogue
tachysystole, not for VBAC

for PPH- 1000 mcg PR/SL, hyperthermia

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14
Q

Levothyroxine
Indication
Dose
MOA
Side effects/CI

A

thyroid replacement
1mg/kg/day PO
synthetic levothyroxine
due to overtreatment

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15
Q

PTU
Indication
Dose
MOA
Side effects/CI

A

hyperthyroid
100 mg PO TID
blocks thyroid hormone synthesis (interferes with TPO)
hepatotoxicity

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16
Q

Hemabate
Indication
Dose
MOA
Side effects/CI

A

uterotonic
0.25 mg IM q15 min for max of 8 doses
PGF2 a analogue
asthma

17
Q

Methergine
Indication
Dose
MOA
Side effects/CI

A

uterotonic
0.2 mg IM q2h
increases smooth muscle contractions/tone
HTN,CAD, raynauds

18
Q

Tranexamic acid
Indication
Dose
MOA
Side effects/CI

A

hemorrhage
1g IV over 10 min
inhibits fibrinolysis and plasmin activity
headaches

19
Q

Ancef
Indication
Dose
MOA
Side effects/CI

A

antibiotic ppx, PPH
2g
broad spectrum
allergy

20
Q

micronized progesterone
Indication
Dose
MOA
Side effects/CI

A

short cervix
200 mg PV qhs
maintains uterine quiescents; prevents fetal membrane apoptosis
abnormal discharge

21
Q

lidocaine
Indication
Dose
MOA
Side effects/CI

A

local anesthesia
60 cc 0.5 with epi (30 cc without) max
7 cc/kg with epi, 4 cc/kg without
blocks Na channels and nerve conduction
Seizure, MI, allergy

22
Q

amp/gent (clinda)

A

chorio
amp: 2g q6h - gram positive
gent: 5 mg/kg q24h - gram negatives
clinda: 900 mg q8h - mrsa and anaerobes
broad spectrum allergy

23
Q

ancef for retained placenta

A

2g x1 dose

24
Q

heparin MOA

A

potentiates ATIII to inactive thrombin (as well as other coag factors like Xa)
prevents conversion of fibrinogen to fibrin

25
Q

insulin
Indication
Dose
MOA
Side effects/CI

A

diabetes
0.7-1 u/kg/day total.
regulates metabolism of carbohydrates, synthesizes glycogen
hypoglycemia

26
Q

Metformin
Indication
Dose
MOA
Side effects/CI

A

diabetes
500 mg PO daily to BID
decreases hepatic glucose production and intestinal absorption
lactic acidosis

27
Q

Glyburide
Indication
Dose
MOA
Side effects/CI

A

2.5 mg PO daily
stimulates insulin release from beta cells
hypoglycemia

28
Q

diabetes in labor

A

1u/hr if FS >120
in D5 1/2 NS
regular insulin

29
Q

doxylamine-pyridoxine
Indication
Dose
MOA
Side effects/CI

A

nausea and vomiting in pregnancy
10mg/10 mg; 2 tabs qhs, max 4/day
antihistamine, gaba activity
fatigue, dizziness, palpitations

30
Q

Nifedipine tocolysis

A

10-30 mg loading
20 mg every 6 hours for 48 hours
Max dose is 180

31
Q

Indomethacin tocolysis dose

A

50-100 mg loading
25 mg every 6 hours for 48 hours
Max dose is 200 mg daily

32
Q

Pcn GBS PPx
Ancef GBS PPx

A

5 million units for loading dose
2.5 million for maintenance q4h

2g initial and 1 g q8 h

Abog oral boards (17 decks)

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