GYN- Surgery Flashcards
Caprini scores and corresponding treatmetns
Score 1-2: mechanical ppx
Moderate, score 3-4: pharmacologic or mechanical ppx, if high risk for bleeding then mechanical ppx
High: score >5: pharmacologic plus mechanical. if high risk for bleeding, mechanical until bleeding risk diminishes, then add pharmacologic
High risk + Cancer: > 5: pharm + mechanical + extended duration post discharge. If high risk for bleeding, then mechanical until bleeding risk decreases, then add pharm
High risk and LDUH/LMWH contraindicated: fondaparinux or mechanical or both
MOA of fondaparinux
Dose for dvt
indirect factor Xa inhibitor. equivalent efficacy to LMWH, for people with hx of HIIT
5-10 mg based on weight ( 5 mg of <50 kg, 7.5 mg qd if 50-100 kg, and 10 mg qd if >100 kg)
when to stop/start LMWH with regional anesthesia
stop ppx dosing 12h before catheter placement or removal. Don;t restart for at least 4 hours after catheter removal
when to start/stop LDUH w/ regional anesthesia
can be administered 4-6h before catheter placement or removal
can restart ppx dosing right after catheter removal. can also be given with catheter in situ. ppx dosing not associated with increased risk of hematoma
what is high d dimer level
500
heparin MOA
loading dose for DVT/PE
maintenance dose
prevention
complications
MOA: co factor for antithrombin . increases inhibition of thrombin and factor Xa
Loading: DVT- 100 u/kg; PE-150u/kg
maintenance: 15-25 u/kg/hr. convert to warfarin or LMWH (if preg) when stable. Warfarin 5 mg qd then INR goal 1.5-2.5x normal
prevention: 5000u BID, TID in pts with gyn cancer
PE-8-10k units BID
complicatons: osteoporosis, alopecia, thrombocytopenia
reversal agent for LDUH
protamine sulfate
when to redose abx
1) obese- give 3g ancef if >120kg
2) lengthy procedure- give additional dose if 4 hours or more from last dose
3) excessive blood loss (>1500 cc)
GYN surgeries you would give abx for (6)
1) Hysterectomy - ancef
2) uterine evacuation- doxycycline 200 mg before (within one hour)
3) colporrhaphy - ancef
4) vaginal sling placement- cefazolin
5) laparotomy without entry into bowel or vagina (can consider ancef)
6) chromotubation/HSG: doxy 100 BID x5d if hx of PID or find abnormal tubes
treatment for dilated fallopian tubes
seen on HSG
doxycycline 100 mg BID for 5 days
alternative treatment if allergic to PCN
if NOT anaphylaxis, urticaria (hives) or bronchospasm or SJS, toxic epidermal necrolysis- can give them ancef
-immediate hypersensitivity (IgE mediated), occurs within 1 hour
-delayed hypersensitivity, occurs days later (pruritic rash, urticarial) use of ancef is generally acceptable
if either of those- clinda 900 mg q6h OR flagyl 500 mg
PLUS gentamicin 5 mg/kg OR aztreonam 2g
what to give patients with MRSA
single preoperative IV dose of vacomycin (15 mg/kg) up to 2h before incision
how to repair bladder injury
assess location with respect to trigone
close in three layers if possible
1) non locking continuous 3-0 Vicryl through mucosa and submucosa
2) interrupted 3-0 vicryl to muscularis layer
3) interrupted 2-0 vicryl to paravesical fascia layer
backfill bladder with die (sterile milk, indigo carmine)
leave catheter for 3-7 days, no antibiotics
ureteral injury
>5 cm above UVJ
ureteroureterostomy (end to end anastomosis)
spatulate ends
4-6 interrupted sutures of 4-0 chromic through full thickness of cut edge
drain
ureteric stents and bladder cath x10 days
ureteral injury
<5 cm above UVJ
ureteroneocystotomy
consider psoas hitch or boari flap if unrepairable without tension
transureteroureterostomy (implant ureter into contralateral ureter)
always consider nephrostomy
Bowel injury and repair
small bowel lac parallel to long axis of bowel
closure end to end (avoid narrowing of lumen)
Mucosa/submucosa in single layer with interrupted 3-0 vicryl
muscularis/serosa with 3-0 non absorbable suture (silk or vicryl)
can do interrupted or continuous
small bowel laceration at right angle to long axis of bowel
closure now side to side
if small bowel injury occurred and pt got preop antibiotics, don’t need additional abx
pfannensteil
Joel Cohen
Cherney
Maylard
midline
pfanny: separation of sheath from rectus, hernia uncommon
Joel cohen- minimze sharp dissection leading to quick entry. more cephalad than pfanny. straight line.
cherney- excise rectus tendon from pubis, can damage inf epigastrics, good exposure of lower abd, bleeding hematoma inc risk
maylard- transection of rectus muscle with ligation of inferior epigastric vessels. No separation of sheath from rectus. inc bleeding hematoma. good visualization of lower abd
midline: quick entry, good exposure, less blood loss, less nerve injury, easy to extend, inc risk of dehisence
Bipolar instrument with hysteroscopy
What fluid medium?
Normal saline
+ electrolytes
isotonic
Don’t get hyponatremia, get volume overload and right sided heart failure, pulmonary edema and death
treat fluid overload with IV lasix (20-40 mg)
Monopolar instrument with hysteroscopy
What fluid medium
No electrolytes
Hypotonic (1.5 glycine and 3% sorbitol)
isotonic solutions (5% mannitol)
what happens when you absorb hypotonic electrolyte free fluids
1.5% glycin and 3% sorbitol
hypoosmolality, hyponatremia, cerebral edema, hypotonic encephalopathy, permanent neuro injury, heart failure, pulm edema, and death
5% mannitol is less likely to cause hypoosmolality, can lead to hyponatremia
how to treat symptomatic hyponatremia
infusion of 3% sodium chloride (0.5-2 ml/kg/hr)
how to treat asymptomatic hyponatremia
fluid restriction
careful monitoring of urine output
what are the two clicks with veress needle
how much pressure to inflate abdomen
rectus sheath and then peritoneum
25-30 mm hg
who should get preop EKG
HTN
DM
smoking
family hx of CAD
wells clinical criteria and scores
> or equal to 4: PE likely; <4: PE unlikely
clinical sx of DVT- 3 points
other dx less likely: 3 points
heart rate >100: 1.5 points
immobilization: 1.5 points
previous DVT/PE: 1.5 points
hemoptysis: 1 point
malignancy 1 point
what do you do if you have elevated wells score
get d dimer
if d dimer is <500. PE exlcuded
if d dimer is >500 : CTPA aka ct angio with contrast
cannot get d dimer if pregnant or post op (will be elevated)
if PE is likely - go straight to CT angio
treatment dose of lovenox for PE
1.5 mg/kg sc daily for 5-10 days, at three days then warfarin
or 1 mg/kg BID
therapeutic monitoring for heparin and lovenox
heparin: aPTT 1.5-2.5X
lovenox: anti factor xa activity 0.6-1.0 units/mL, test 4 hours after dose