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Pharm II > Meds and classes > Flashcards

Meds and classes Flashcards

1
Q

*Quinidine (Quinora)

A

*Class IA sodium channel blocker

Cardiac arrhythmia

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2
Q

Procainamide (Pronestyl)

A

Class IA sodium channel blocker

Cardiac arrhythmia

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3
Q

*Lidocaine (xylocaine)

A

*Class IB sodium channel blocker

cardiac arrhythmia

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4
Q

*Flecainide (Tambocor)

A

*Class IC sodium channel blocker

cardiac arrhythmia

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5
Q

*Propanolol (Inderal)

A

*Class II Beta blocker (nonspecific)
(-) inotropic agent
(cardiac arrhythmia)

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6
Q

Acebutolol (Sectral)

A

Class II beta blocker (B with ISA)
(-) inotropic agent
(cardiac arrhythmia)

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7
Q

Esmolol (Brevibloc)

A

Class II Beta blocker
(-) inotropic agent
(cardiac arrhythmia)

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8
Q

Metroprolol (Lopressor)

A

Class II Beta Blocker (B1 specific)
(-) inotropic agent
Cardiac arrhythmia
also used in CHF

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9
Q

Nadolol (Corgard)

A

Class II Beta blocker (nonspecific)
(-) inotropic agent
Cardiac arrhythmia

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10
Q

Timolol (Blocadren)

A

Class II Beta Blocker (nonspecific)
(-) inotropic agent
Cardiac Arrhythmia

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11
Q

Atenolol (Tenormin)

A

Class II Beta Blocker (B1 specific)
(-) inotropic agent
Cardiac Arrhythmia

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12
Q

Amiodarone (Cordarone)

A

Class III K+ channel blocker (prolong repolarization)

Cardiac Arrhythmia

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13
Q

Sotalol (Betapace)

A

Class III K+ channel blocker (prolong repolarization)

Cardiac Arrhythmia

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14
Q

*Verapamil (Calan, Isoptin)

A

*Class IV CCB

Cardiac arrhythmia

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15
Q

Diltiazem (Cardizem)

A

Class IV CCB

Cardiac arrhythmia

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16
Q

Adenosine (adenocard)

A

Misc: natural nucleoside that enhances K+ conductance and inhibits Ca influx
Cardiac Arrhythmia

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17
Q

Digoxin (lanoxin)

A

Misc

Cardiac Arrhythmia

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18
Q

Magnesium

A

Misc. Mechanism unknown

DOC for Torasde de pointes and Digitalis induced arrhythmia

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19
Q

Potassium

A

Misc. Increases serum K+, depolarization

Cardiac Arrhythmia

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20
Q

*Acetazolamide (Diamox)

A

*Carbonic Anhydrase Inhibitor

Diuretic

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21
Q

Brinzolamide (Azopt) topical

A

Carbonic Anhydrase inhibitor

Diuretic

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22
Q

Dorzolamide (Trusopt) topical

A

Carbonic Anhydrase Inhibitor

Diuretic

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23
Q

*Furosemide (Lasix)

A

*Loop Diuretic

used in CHF, HTN

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24
Q

Bumetanide (Bumex)

A

Loop Diuretic

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25
Q

Torsemide (Demadex)

A

Loop Diuretic

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26
Q

Ethacrynic Acid (Edecrin)

A

Loop Diuretic

used in CHF

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27
Q

*Hydrochlorothiazide (Esidrix)

A

*Thiazide Diuretic

used in CHF, HTN (DOC)

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28
Q

Chlorothiazide (Diuril)

A

Thiazide Diuretic

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29
Q

Chlorthalidone (Hygroton)

A

Thiazide Diuretic

- cmpd related to thiazides

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30
Q

Metolazone (Mykrox)

A

Thiazide Diuretic
- compound related to thiazides
Used in CHF, HTN

31
Q

Quinethazone (Hydromox)

A

Thiazide Diuretic

- compound related to thiazides

32
Q

Indapamide (Lozol)

A

Thiazide Diuretic
-compound related to thiazides
*direct vasodilator, hepatic metabolism
Used in CHF, HTN

33
Q

*Amiloride (Midamor)

A

*K+ sparing Diuretic (Direct inhibitor of Na flux)

Used in CHF, HTN

34
Q

Triamterene (Dyrenium)

A

K+ sparing Diuretic (direct inhibitor of Na flux)

Used in CHF

35
Q

Spironolactone (Aldactone)

A

K+ sparing diuretic (Aldosterone antagonist)

Used in CHF

36
Q

Eplerenone (Inspra)

A

K+ sparing diuretic (Aldosterone Antagonist)

Used in CHF, HTN

37
Q

*Mannitol (Osmitrol)

A

*Osmotic Diuretics

38
Q

Isosorbide (Ismotic)

A

Osmotic Diuretic

39
Q

Glycerin (Osmoglyn)

A

Osmotic Diuretic

40
Q

Urea (Ureaphil)

A

Osmotic Diuretics

41
Q

Desmopressin

A

ADH agonist, synthetic ADH

42
Q

Conivaptan (Vaprisol)

A

ADH antagonist; non peptide V1 and V2 receptor antagonist

43
Q

Tolvaptan (Samsca)

A

ADH antagonist

non peptide V2 vasopressin receptor antagonist

44
Q

Demeclocycline (Declomycin)

A

ADH antagonist
blocks V2 receptor 2nd messenger system
(use dc bc of vaptans)

45
Q

Lithium

A

ADH antagonist

competes for Na excretion in renal tubules

46
Q

Digoxin (Lanoxin)

A

Digitalis
+Inotropic/contractile agent for CHF
inhibits Na/KATPase pump

47
Q

Inamrinone (Inocor, Amrinone)

A

PDE inhibitor (bipyridines)
+Inotropic/contractile agent for CHF
inhibit cAMP PDE, increase Ca influx, vasodilation

48
Q

Milrinone (primacor)

A

PDE inhibitor (bipyridines)
+Inotropic/contractile agent for CHF
inhibit cAMP PDE, increase Ca influx, vasodilation

49
Q

*Dobutamine (Dobutrex)

A

*Sympathomimetics
+inotropic/contractile agent for CHF
selective B1 agonist (less tachycardia)

50
Q

Dopamine (Intropin)

A

Sympathomimetics
+ionotropic/contractile agent for CHF
acts on D1 (renal vasodilation), B1 (+inotropic) and alph (vasoconstriction)

51
Q

What four drugs reduce CHF mortality

A

1) Aldosterone antagonists (Spironolactone, Eplerenone)
2) Beta blockers (olol)
3) ARBs (artan)
4) ACE inhibitors (pril)

52
Q

*Captopril (Capoten)

~all “pril”

A

*ACE inhibitors
Diminish cardiac workload in CHF pt (backbone tx)
block angiotensin I to II conversion

53
Q

*Losartan (Cozaar)

~all “artan”

A

*ARB
diminish cardiac workload in CHF pts
block ang II from bindign to ATI receptor

54
Q
  • Carvedilol (Coreg)

* Metroprolol (Lopressor)

A

*B Blocker

(-) inotropic/contractile agent, decreases cardiac workload (HR, remodeling) in early stage CHF

55
Q

*Sodium Nitroprusside (Nitropress)

A

Vasodilator
~reduce preload and/or afterload and reduce remodeling of heart for CHF pt
~also used in acute angina

56
Q

*Hydralazine (Apresoline)

A

Vasodilator

~Reduce preload and/or afterload and reduce remodeling of heart for CHF pt

57
Q

*Isosorbide dinitrate (Isordil)

A

Vasodilator

~Reduce preload and/or afterload and reduce remodeling of heart for CHF pt

58
Q

What general types of meds treat HTN

*note: combos from different groups increase efficacy and may decrease toxicity

A

Diuretics,
Sympathoplegic agents (a2 agonists, a1 blockers, B blockers (all forms)) –> decrese SNS tone
Vasodilators (NO, CCB, K channel openers, D1 receptor stimulant)
ACE inhibitors
ARBS

59
Q

What general types of meds treat Cardiac Arrhythmias

A 
Class I Na channel blockers
Class II B blockers
Class II K channel blockers (prolong repolarization)
Class IV CCB
others (Mg, K, Digoxin, Adenosine)
60
Q

What general types of Diuretics are there

A 
CA inhibitors
Loop Diuretics
Thiazide Diuretics
K+ sparing diuretics (aldo antagonists and direct inhibitors of Na flux)
Osmotic Diuretics
ADH agonists and antagonists
61
Q

*Clonidine (Catapres)

A

alpha 2 agonist
*Centrally acting Sympatholytic for HTN pt
decrease peripheral SNS activity on heart and BV = vasodilation

62
Q

*Methyldopa (Aldomet)

A

alpha 2 agonist
Centrally acting sympatholytic for HTN pt
Decreases peripheral SNS activity on heart and BV = vasodilation

63
Q

*Prazosin (minipress)

A

alpha 1 blocker
vasodilation –> decrease BP
for HTN

64
Q

Doxazosin (Cardura)

A

alpha 1 blocker
Vasodilation –> decrease BP
for HTN

65
Q

ACE suffix

66
Q

B blocker suffix

67
Q

a1 blocker suffix

68
Q

ARB suffix

69
Q

CCB suffix (generally)

A

dipine

*but have verapamil and diltiazem

70
Q

Non selective B blockers

A

*Propranolol (Inderal)
Nadolol (Corgard)
Timolol (Blocadren)

*NAh TIM’s a non selective PRO

71
Q

Selective B1 blockers

A

*Metroprolol (Lopressor)
Atenolol (Tenormin)
Nebivolol (Bystolic)
Acebutolol (Sectral)

~for HTN
*beta 1 met athena’s new ace”

72
Q

B blockers with ISA

A

*Acebutolol (Sectral)
Pindolol (Visken)

~for HTN
*Pin Isa {an} ace!

73
Q

Combined Alpha and B blockers

A

Carvedilol (Coreg)
Labetalol (Normodyne)

~for HTN
*combine lab carvings

Pharm II (12 decks)

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