Meds Flashcards
specific receptors sites located throughout the body for the endogenous sympathetic neurotransmitters norepinephrine and epinephrine
Adrenergic receptors
block SNS stimulation by competing with norepinephrine and epinephrine
beta-adrenergic blocking drugs
interupt stimulation of the SNS @ the alpha1-adrenergic receptors
-doxazosin
-prazosin
-terazosin
Cause both arterial and venous dilation.
-Decrease peripheral vascular resistance and bp.
-treat hypertension
-Alpha1-adren. receptors in the prostate and bladder.
decrease smooth muscle contration of the bladder neck and the prostatic portion of the urethra
Alpha1-adrenergic beta blockers
alfuzosin doxazosin phenoxybenzamine phentolamine (Regitine) tamsulosin (Flomax)
Sin and ine; Alphas
Carvedilol labetalol nadolol penbutolol pindolol propranolol sotalol timolol
Betas; lol
acebutolol atenolol betaxolol bisoprolol esmolol nebivolol metoprolol
Cardioselective; lol
nandrolone
oxandrolone
oxymetholone
Anabolic Steroids olone
finasteride
dutasteride
5-Alpha Reductase Inhibitors; BPH
goserelin
leuprolid
triptorelin
Gonadotropin-releasing hormone analogues
minoxidil
Perpheral Vasodilator
danazol
fluoxymesterone
methyltestosteron
testosterone
Other Androgens
bicalutamide
flutamide
nilutamide
Antiandrogens (mide)
sildenafil
tadalafil
vardenafil
alprostadil
Drugs for ED (fils)
formation of blood filled cavities from androgenic steroid use and testosterone
peliosis of the liver
antiinflammatory; analgesic effects good for opiate-addicted patients has non-addicting properties -short term use (up to 5 days) PO or IV/IM manage moderate/severe acute pain Side effects: renal impairment, edema, GI pain, dyspepsia, nausea
Ketorolac (Torado)
mostly commonly used propionic acid drugs
-gout, arthritis, musculoskeletal disorders
-antipyretic actions
Naproxen 2nd most NSAIDs used
Ibuprofen (Motrin, Advil) NSAID
relief of gout
-inhibition of the enzyme xanthine
oxidase,prevents uric acid production.
allopurinol (zyloprim)
derivative of allopurinol
Oxypurinol
Uloric non-purine selective inhibior
Febuxostate
cont. inflammation and low grade infection of the bronchi
chronic bronchitits
cond. in which the air spaces enlarge as a result of the destruction of the alveolar walls.
Emphysema
Anticholinergics Leukotriene receptor antagonists Beta agonists and xanthine derivatives corticosteroids mast cell stabilizers
COPD meds
used to quickly reduce airway constriction and restore airflow to normal.
-imitate the effects of norepinephrine on beta receptors
sympathomimetic bronchodilators
Betas
Albuterol-beta2
levalbuterol
short acting bronchodilators
salmeterol
long acting bronchodilators
ipratropium (Atrovent)
tiotropium (spiriva)
prevention of bronchospasm assoc with chronic bronchitis or emphysema (not for management of acute symptoms)
slow and prolonged action; inhaler
anticholingergics; pium
bronchodilator
montelukast (singulair) B
~blocking leukotriene D4 receptors to augment the inflammatory response.
-block inflammatory process in asthma
Antileukotriene Drug
treatment in pulmonary diseases for the antiinflammatory effects.
PO, inhaled, or IV. & enhancing activity of beta agonists
For severe cases of asthma
fluticasone (Flovent)
methylpredisolone
fluticasone propionate (Flonase)
Corticosteroids