meds Flashcards
Lomotil
diphenoxylate/atropine
Lomotil
diphenoxylate/atropine
Action:
difenoxine binds to gut wall opioid receptors, inhibits peristalsis. Atropine present to discourage overdose.
Lomotil
diphenoxylate/atropine
Route:
1-2 tabs PO bid-qid PRN
2 tabs qid no more than 8 tabs or 40ml/day
D/C after 48h if no improvement
Lomotil
diphenoxylate/atropine
Side effects:
Nausea, vomiting, anorexia, abdominal pain, paresthesia, euphoria, depression, confusion, sedation, gingival hyperplasia
Lomotil
diphenoxylate/atropine
Lab monitoring:
Monitor before for liver disease or volume depletion
Lomotil
diphenoxylate/atropine
Precautions:
presence of hepatic impairment
obstructive jaundice
risk of hepatic coma
many drug interactions
Imodium
loperamide
Imodium
loperamide
Action:
binds gut wall opioid receptors. inhibits peristalsis
increases anal sphincter tone
Imodium
loperamide
Route:
2mg PO per dose
start 4 mg x1 then 2mg po after each loose stool
max 16mg/day
Imodium
loperamide
Side effects:
constipation
nausea, abdominal cramps, dizziness
Serious: urinary retention
Imodium
loperamide
Lab monitoring:
monitor liver function labs for hepatic impairment
Imodium
loperamide
Precautions:
many drug interactions
monitor parameters for s/sx CNS toxicity if hepatic impairment
Kaopectate
Pepto-Bismol
bismuth subsalicylate
Kaopectate
Pepto-Bismol
bismuth subsalicylate
Action:
reduces secretions binds bacterial toxins
possesses antimicrobial effects
Kaopectate
Pepto-Bismol
bismuth subsalicylate
Route:
2 tab PO q1h PRN
max 4200mg/24h
30ml PO q1h PRN
H pylori infections 2 tab PO qid x 7-14 days