Medicine Flashcards

1
Q

how to divide codeine dose to morphine?

A

divide by 10

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2
Q

how to divide PO morphine dose to s/cut morphine?

A

divide by 2

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3
Q

in palliative, drug given for agitation?

A

haloperidol
midaz

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4
Q

in palliative, drug given for hiccups?

A

chlorpromazine

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5
Q

Tx for alzheimers?

A

donepezil (causes bradycardia)
memantime

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6
Q

diagnosis of dementia?

A

MMSE <24/30
bloods and CTB for organic cause

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7
Q

drug class of donepezil?

A

Ach inhibitors

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8
Q

drug class of memantine?

A

NMDA receptor antagonist

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9
Q

what rises in MTC?

A

calcitonin

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10
Q

what is elevated in non seminoma testicular tumour?

A

AFP

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11
Q

anaphylaxis doses?

A

adult 500mcg 1:1000
6-12yrs 300mcg
6mnths - 6yrs 150mcg

can repeat every 5 mins

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12
Q

Tx for PBC?

A

ursedeoxycholic acid

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13
Q

What infections occur in IgA deficiency?

A

resp
UTI
gastro

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14
Q

types of HS?

A

I - immediate
II - antibody (blood transfusion)
III - immune complex
IV - contact dermatitis

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15
Q

what is the bad cholesterol?

A

LDL

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16
Q

blood tests in SIADH?

A

urine osmolality increased
urina Na increased
low Na

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17
Q

what is pellagra? features?

A

Vit B3 def
dementia
diarrhoea
dermatitis

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18
Q

who gets NIV in COPD exacerbations?

A

pH 7.25-7.35

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19
Q

Tx for asthma?

A

ICS / formeterol
+ MART (fostair)

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20
Q

Tx for COPD?

A

SABA/SAMA
+
LABA/LAMA
+ ICS if any asthma features

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21
Q

most common lung ca?

A

adeno

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22
Q

what lung ca is cavitating?

A

squamous
causes hypercalcaemia (PTH)

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23
Q

features of small cell lung ca?

A

central
ADH/ACTH secretion
aggressive

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24
Q

features of eGPA?

A

asthma
sinus problems
pANCA

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25
Q

features of GPA?

A

renal
epistaxis
saddle nose
cANCA

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26
Q

Tx for bronchitis?

A

doxy

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27
Q

red jelly sputum?

A

klebsiella

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28
Q

features of kartagnerer’s?

A

dextrocardia
infertile
bronchiectasis

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29
Q

examples of transudate pleural effusion?

A

<30
HF
ascites

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30
Q

examples of exudate pleural effusion?

A

> 30
infections
cancer
LDH >2/3 of normal LDH

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31
Q

who cannot get buprion for smoking cessation?

A

epileptics

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32
Q

what pneumonia causes hyponatraemia?

A

legionella

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33
Q

does bell’s palsy spare forehead?

A

NO
LMN - affected

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34
Q

wernicke’s vs broca?

A

wernicke - cannot comprehend - temporal lobe

broca - expressive (cannot speak) - frontal lobe

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35
Q

prophylaxis for cluster headache?

A

verapamil

36
Q

prophylaxis for migraine?

A

propranolol

37
Q

prophylaxis for trigeminal neuralgia?

A

carbamazepine

38
Q

features of progressive SN palsy?

A

falls
parkinsomism
cognitive impairment

39
Q

features of normal pressure hydrocephalus?

A

incontinent
dementia
gait abnormalitis

40
Q

Tx for generalised epilepsy?

A

sodium valp
lamotrigine

41
Q

features of MSA?

A

parkinsomism
cerebellar signs
autonomic issues (erectile dysfunction, postural hypotension)

42
Q

Tx for absence seizures?

A

ethosux

43
Q

Tx for focal seizures?

A

lamotrigine
leveteracitam

44
Q

features of parietal seizures?

A

parasthesia

45
Q

features of temporal seizures?

A

aura
automatisms

46
Q

features of frontal seizures?

A

head/leg movements

47
Q

TACI stroke?

A

hemiparesis/numbness
hom hemianopia
higher cognitive dysfunction

48
Q

PACI stroke?

A

2/3 of
hemiparesis/numbness
hom hemianopia
higher cognitive dysfunction

49
Q

POC stroke?

A

1 of
cerebellar signs
LOC
hom hemianopia

50
Q

when does carotid intervention get offered post stroke?

A

> 50% stenosis

51
Q

windows for stroke Tx?

A

thrombolysis 4.5 hrs
thrombectomy 6 hrs

52
Q

Lacunar stroke features?

A

isolated hemiparesis/hemisensory disturbance

53
Q

how to tell if ACA or MCA stroke?

A

ACA lower limbs worse than UL (MCA opposite)

54
Q

features of 3rd nerve palsy?

A

down and out
ptosis

55
Q

features of AIN?

A

sterile pyuria
white castas

56
Q

HUS vs IgA vs post strep GN?

A

HUS
E coli
thrombocytopenia
AKI

IgA
haematuria
URTI (days after)

post strep
weeks after
proteinuria

57
Q

what abg does diarrhoea cause?

A

met acidosis
normal anion gap

58
Q

what abg does vomiting cause?

A

metabolic alkalosis

59
Q

how much glucose should we get per day?

A

50-100g

60
Q

Tx for nephrogenic DI?

A

thiazides

61
Q

what causes kaposi’s sarcoma?

A

HHV8

62
Q

Tx for BV?

A

metro

63
Q

Tx for chlamydia?

A

doxy/azithro

64
Q

Tx for gonorrhoea?

A

ceftriaxone

65
Q

what HSV causes oral vs genital ulcers?

A

1 - oral
2 - genital

66
Q

which HPV causes warts vs cancer?

A

warts 6+11
cancer 16+18

67
Q

TB drug side effects?

A

R - red yellow tears
I - Peripheral neuropathy, hepatits
P - gout, athralgia
E - optic neuritis

68
Q

live vaccines?

A

BCG
MMR
Polio
Yellow fever
typhoid
flu

69
Q

Tx for meningitis contacts?

A

PO cipro

70
Q

blood results in addisons?

A

low
Na, glucose
low cortisol and aldosterone

high K

met acidosis

71
Q

Ix for addisons?

A

short synacthen

72
Q

Blood result for cushings?

A

met alkalosis

73
Q

LH and FSH in kallman vs kleinfelter?

A

kallman - low
kleinfelter - high

74
Q

blood results in Conn’s?

A

low K
met alkalosis
hypertensive

75
Q

blood results in sick euthyroid?

A

low TSH and T4

76
Q

blood results in de quervains?

A

low TSH
high Tv
tender goitre

77
Q

treatment for polycythaemia vera?

A

aspirin
venesections

78
Q

Tx for VTE?

A

provoked 3 months
unprovoked 6 months

79
Q

factors affected in haemophilia?

A

A - VIII
B - IX (christmas)

80
Q

Tx for tumour lysis?

A

allopurinol

81
Q

Blood results in haemophilia A?

A

prolonged APTT
normal pT

82
Q

features of behcets?

A

vasculitis
ulcers
increased VTE risk

83
Q

common cause of meningitis?

A

S pneumonia

84
Q

meningitis Tx?

A

cefotaxime/ceftriaxone

+ amox if >50yrs

85
Q

AKI staging?

A

1 - creat 1.5-1.9 x baseline

2 - 2-2.9

3 - 3.0 / 0.3ml/kg/hr of urine in 24hrs