December 1 Flashcards

1
Q

what drug is used in pts with bilateral adrenal disease?

A

spironolactone

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2
Q

blood results in myeloma?

A

ESR and CRP high
paraprotein and BJP
Increase in marrow plasma cells

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3
Q

bone lesions in myeloma?

A

lytic

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4
Q

lead poisoning?

A

GI upset
weakness
kidney injury

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5
Q

TCA poisoning?

A

tachy
drowsy
dry mouth
hallucinations
SVT

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6
Q

salicylate poisoning?

A

tinnitus
sweating
met acidosis
hypoghlycaemia

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7
Q

iron poisoning?

A

GI bleed
met acidosis
hypovolaemia

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8
Q

features of fragile X?

A

large testicles
MV prolapse

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9
Q

features of edwards? what chromosome?

A

trisomy 18
young death (weeks)

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10
Q

features of Pierre robin?

A

pushed back tongue
underdeveloped jaw

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11
Q

do you give Abx for E coli diarrhoea?

A

NO
increase risk of HUS

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12
Q

what tumours occur in MEN2a?

A

MTC
phaechromocytoma
hyperparathyroidism

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13
Q

what tumours occur in MEN1?

A

Pituitary adenomas
pancreatic tumours
hyperparathyroidism

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14
Q

where is the mutation in MEN?

A

RET gene

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15
Q

antibody in PBC?

A

AMA

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16
Q

what IBD is PSC more assoc with?

A

UC

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17
Q

e.g of 1st and 2nd gen antipsychotic?

A

1st - haloperidol
2nd - olanzapine

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18
Q

what is sore - epi of scleritis?

A

SCLERITIS

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19
Q

what electrolyte abnormality do SSRis cause?

A

hyponatraemia

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20
Q

how long should anti depressants be continued for?

A

6 months

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21
Q

how long do symptoms need to last to be classified a depressive illness?

A

2 weeks

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22
Q

atypical antipsychotics increase risk of what in elderly?

A

VTE
stroke

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23
Q

when should clozapine be used?

A

if two previous antipsychotics have been tried and not worked

24
Q

what is raised in anorexia?

A

GH
glucose
cortisol
cholesterol
caritonaemia

25
Q

what antidepressant should be given post MI?

A

sertraline

26
Q

what arrythmia can citalopram cause?

A

torsades

27
Q

what antidepressant should be avoided on warfarin?

A

citalopram

28
Q

what is the difference between conversion and somatisation disorder?

A

conversion - FND
somatisation - symptoms but not accepting of neg tests, >years

29
Q

what is the Tx for PTSD?

A

venlaflaxine
SSRIs

30
Q

what cancer does COCP protect against?

A

ovarian

31
Q

how long after LMP can the menopause be classified as?

A

12 months if >50
24 if <50

32
Q

Tx for urge incontinence?

A

oxybutynin

33
Q

Tx for stress incontinence?

A

duloxetine

34
Q

what antibody indicates drug induced lupus?

A

anti histone

35
Q

cause of groin pain in young adults? snapping

A

femeroactetabular impingement

36
Q

CREST syndrome features?

A

calcinosis
raynauds
eosphageal dysmotility
scelrodactyly
telangectasia

37
Q

what abx should be avoided if on MTX?

A

co trim
trimethoprim

38
Q

pagets features?

A

old man
bone pain
ALP rise

39
Q

osteomalacia features?

A

low Ca
low P
raised ALP
raised PTH

40
Q

secondary hyperparathyroidism bloods?

A

high ALP
high P
high PTH
renal disease

41
Q

what T score is diagnostic for osteoporosis?

A

-2.5

42
Q

when should a DEXA scan be repeated?

A

after 5 yrs bisphosphonates

43
Q

what is waiters tip palsy?

A

erb duchenne
C5/C6
arm is IR, elbow extended

44
Q

what is klumpke injury?

A

C8 T1
claw hand (MCP extended, IP flexed)

45
Q

gestational diabetes Tx ladder?

A

diet
metformin
insulin (if metformin and diet not working)

46
Q

when should pregnant women get aciclovir?

A

> 20 weeks
within 24hrs of rash

47
Q

when should pregnant women get VZIG?

A

7-14 days post exposure

48
Q

Tx for lichen planus?

A

clobetasone butyrate

49
Q

ABPI for arterial disease?

A

<0.9

50
Q

Tx for keloids?

A

intralesional triamcinolone

51
Q

what drugs worsen psoriasis?

A

B blocker

52
Q

Tx for capillary haemangioma?

A

propranolol

53
Q

Tx for flexural psoriasis?

A

coal tar
steroid

54
Q

features of lichen planus?

A

purple pruritis rash
flexor surfaces
wickhams striae
oral

55
Q
A