December 1 Flashcards
what drug is used in pts with bilateral adrenal disease?
spironolactone
blood results in myeloma?
ESR and CRP high
paraprotein and BJP
Increase in marrow plasma cells
bone lesions in myeloma?
lytic
lead poisoning?
GI upset
weakness
kidney injury
TCA poisoning?
tachy
drowsy
dry mouth
hallucinations
SVT
salicylate poisoning?
tinnitus
sweating
met acidosis
hypoghlycaemia
iron poisoning?
GI bleed
met acidosis
hypovolaemia
features of fragile X?
large testicles
MV prolapse
features of edwards? what chromosome?
trisomy 18
young death (weeks)
features of Pierre robin?
pushed back tongue
underdeveloped jaw
do you give Abx for E coli diarrhoea?
NO
increase risk of HUS
what tumours occur in MEN2a?
MTC
phaechromocytoma
hyperparathyroidism
what tumours occur in MEN1?
Pituitary adenomas
pancreatic tumours
hyperparathyroidism
where is the mutation in MEN?
RET gene
antibody in PBC?
AMA
what IBD is PSC more assoc with?
UC
e.g of 1st and 2nd gen antipsychotic?
1st - haloperidol
2nd - olanzapine
what is sore - epi of scleritis?
SCLERITIS
what electrolyte abnormality do SSRis cause?
hyponatraemia
how long should anti depressants be continued for?
6 months
how long do symptoms need to last to be classified a depressive illness?
2 weeks
atypical antipsychotics increase risk of what in elderly?
VTE
stroke
when should clozapine be used?
if two previous antipsychotics have been tried and not worked
what is raised in anorexia?
GH
glucose
cortisol
cholesterol
caritonaemia
what antidepressant should be given post MI?
sertraline
what arrythmia can citalopram cause?
torsades
what antidepressant should be avoided on warfarin?
citalopram
what is the difference between conversion and somatisation disorder?
conversion - FND
somatisation - symptoms but not accepting of neg tests, >years
what is the Tx for PTSD?
venlaflaxine
SSRIs
what cancer does COCP protect against?
ovarian
how long after LMP can the menopause be classified as?
12 months if >50
24 if <50
Tx for urge incontinence?
oxybutynin
Tx for stress incontinence?
duloxetine
what antibody indicates drug induced lupus?
anti histone
cause of groin pain in young adults? snapping
femeroactetabular impingement
CREST syndrome features?
calcinosis
raynauds
eosphageal dysmotility
scelrodactyly
telangectasia
what abx should be avoided if on MTX?
co trim
trimethoprim
pagets features?
old man
bone pain
ALP rise
osteomalacia features?
low Ca
low P
raised ALP
raised PTH
secondary hyperparathyroidism bloods?
high ALP
high P
high PTH
renal disease
what T score is diagnostic for osteoporosis?
-2.5
when should a DEXA scan be repeated?
after 5 yrs bisphosphonates
what is waiters tip palsy?
erb duchenne
C5/C6
arm is IR, elbow extended
what is klumpke injury?
C8 T1
claw hand (MCP extended, IP flexed)
gestational diabetes Tx ladder?
diet
metformin
insulin (if metformin and diet not working)
when should pregnant women get aciclovir?
> 20 weeks
within 24hrs of rash
when should pregnant women get VZIG?
7-14 days post exposure
Tx for lichen planus?
clobetasone butyrate
ABPI for arterial disease?
<0.9
Tx for keloids?
intralesional triamcinolone
what drugs worsen psoriasis?
B blocker
Tx for capillary haemangioma?
propranolol
Tx for flexural psoriasis?
coal tar
steroid
features of lichen planus?
purple pruritis rash
flexor surfaces
wickhams striae
oral
