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Medications in Anesthesia Cart Flashcards

1
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Atracurium (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

A

MOA: Nondepolarizing neuromuscular blocker,compete with Ach for active binding sites at postsynaptic nicotinic Ach Receptor (competitive antagonists)/ benzylisoquinolinium NMBA(preferred for renal/hepatic patients)
Associated with histamine release

ONSET: 3-5 minutes

DOA: Intermediate(30-50min)

NORMAL DOSE: 0.5 mg/kg, The maintenance dose of atracurium is 0.1 mg/kg, or an infusion at 10 to 20 mcg/kg/min, (f/b neuromuscular monitoring)

METABOLISM: nonspecific plasma esterase-mediated hydrolysis and a nonenzymatic, pH- and temperature-dependent degradation called Hofmann elimination. Laudanosine is the final product of Hofmann elimination,

EXCRETION: half life 21 min, hepatic/renal,no metabolite

USAGE: INTUBATION

RISK: Inhaled anesthetics, some ABTs, inhibit nAChRs and potentiate neuromuscular blockade with non-depolarizing NMBAs.
Patients on Lithium, hypermagnesemic, Hypocalcemic prolonged response to NMJ (depol and non depol)
Acidosis,Hypothermia prolong effects of NMDA
HYPERCALCEMIA: prolongs NDMA

ANTIDOTE: NEOGSTIGMINE /SUGAMMADEX

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2
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Atropine Sulfate: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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3
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Magnesium Sulfate:(Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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4
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Calcium Chloride: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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5
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Calcium Gluconate; (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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6
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Dexamethasone : (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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7
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Dexmedetomidine : (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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8
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Pitocin : (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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9
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Diphenhydramine : (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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10
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Droperidol; (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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11
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Edrophonium: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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12
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Ondansetron: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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13
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Ephedrine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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14
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Isoflurane: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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15
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Nitrous oxide: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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16
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Epinephrine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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17
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Esmolol: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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18
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Etomidate: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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19
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Fentanyl: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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20
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Flumazenil:(Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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21
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Furosemide: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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22
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Glycopyrrolate: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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23
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Heparin: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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24
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Hydralazine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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25
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Labetalol:(Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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26
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Indigo Carmine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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27
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Methergine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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28
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Lidocaine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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29
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Metoclopramide: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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30
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Cisatracurium: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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MOA:Blocks neural transmission at the myoneural junction by binding with cholinergic receptor sites
*more potent than atracurium. In contrast to atracurium, it does not cause histamine release.

ONSET: 2-3 minutes
DOA: 35 to 50 minutes.
NORMAL DOSE: 0.15 to 0.2 mg/kg,
METABOLISM: Hofmann elimination no active metabolites
EXCRETION: half life 22-29 minutes,URINE 95%
USAGE:Neuromuscular blockade for endotracheal intubation, surgery, or mechanical ventilation:

RISK:Caution with hepatic and renal diseases

31
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Midazolam: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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32
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Albuterol: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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33
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Nalbuphine : (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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34
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Naloxone : (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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35
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Neostigmine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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36
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Nitroprusside: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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37
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Famotidine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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38
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Sevoflurane: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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39
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Desflurane: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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Scopolamine:(Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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41
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Phenylephrine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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42
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Propofol :(Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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Protamine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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Rocuronium : (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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45
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Sodium Bicarbonate: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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46
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Succinylcholine :(Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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Vecuronium: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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48
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Verapamil: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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Ketorolac : (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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Ketamine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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51
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Methylene blue:(Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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Glucagon:(Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)

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