Medications in Anesthesia Cart Flashcards
Atracurium (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: Nondepolarizing neuromuscular blocker,compete with Ach for active binding sites at postsynaptic nicotinic Ach Receptor (competitive antagonists)/ benzylisoquinolinium NMBA(preferred for renal/hepatic patients)
Associated with histamine release
ONSET: 3-5 minutes
DOA: Intermediate(30-50min)
NORMAL DOSE: 0.5 mg/kg, The maintenance dose of atracurium is 0.1 mg/kg, or an infusion at 10 to 20 mcg/kg/min, (f/b neuromuscular monitoring)
METABOLISM: nonspecific plasma esterase-mediated hydrolysis and a nonenzymatic, pH- and temperature-dependent degradation called Hofmann elimination. Laudanosine is the final product of Hofmann elimination,
EXCRETION: half life 21 min, hepatic/renal,no metabolite
USAGE: INTUBATION
RISK: Inhaled anesthetics, some ABTs, inhibit nAChRs and potentiate neuromuscular blockade with non-depolarizing NMBAs.
Patients on Lithium, hypermagnesemic, Hypocalcemic prolonged response to NMJ (depol and non depol)
Acidosis,Hypothermia prolong effects of NMDA
HYPERCALCEMIA: prolongs NDMA
ANTIDOTE: NEOGSTIGMINE /SUGAMMADEX
Atropine Sulfate: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Magnesium Sulfate:(Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Calcium Chloride: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Calcium Gluconate; (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Dexamethasone : (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Dexmedetomidine : (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Pitocin : (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Diphenhydramine : (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Droperidol; (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Edrophonium: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Ondansetron: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Ephedrine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Isoflurane: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Nitrous oxide: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Epinephrine: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Esmolol: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Etomidate: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Fentanyl: (Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK:
Flumazenil:(Mechanism of action, onset, duration of action, receptors, normal dose, metabolism, excretion, usage, risks)
MOA: ONSET: DOA: NORMAL DOSE: METABOLISM: EXCRETION: USAGE: RISK: