Medication Administration Flashcards
What are the 3 names for drugs
generic
official - name by which drug is identified in the official publications US Pharmacopeia
trade name
What are ways drugs can be classified
effect on body systems
chemical composition
clinical indication/therapeutic action
What is pharmacokinetics
the effect of the body on the drug - mvmt of drug molecules in the body in relation to the drugs absorption, distribution, metabolism, and excretion
Are acidic drugs well absorbed?
Yes; basic drugs remain ionized/insoluble in acid environments
Elixir
medication in a clear liquid containing water, alcohol, sweeteners, and flavor
Enteric coated
a tablet or pill coated to prevent stomach irritiation
Extended release, and what are other names for it
preparation of a med that allows for slow and continuous release over a predetermined period; aka CR/CRT (controlled release) SR (slow/sustained release) SA (sustained action) LA (long acting) TR (time release)
What is a loading dose
dose that is larger than normal - usually given when a pt is in acute distress and maximum therapeutic effect is desired as quickly as possible
What is a maintenance dose
lower dosage that becomes the usual or daily dosage
Therapeutic Range
the concentration of the drug in the blood serum that produces the desired effect with out causing toxicity
Peak Level
highest plasma concentration - should be measured when absorption is complete
Half-life
amount of time it takes for 50% of the blood concentration of a drug to be eliminated from the body…monitoring this ensures that therapeutic ranges are obtained without reaching toxic levels
Distribution
after drug is absorbed: depends on blood flow to the tissues, the drugs ability to leave the bloodstream and the drug’s ability to enter cells.
**Binding to plasma proteins = unequal distribution/prevents drug from reaching intended site of action
What are 3 factors that affect distribution
binding of drug to plasma proteins = unequal distribution
blood brain barrier= prevents toxins and poisons from reaching the brain
placenta = NOT A BLOOD BARRIER - blood freely flows across it and can drugs can affect the fetus
Metabolism of a drug
aka biotransformation is the change of a drug from its original to its new for
What is the primary site for drug metabolism
liver
Excretion
the process of removing a drug or its metabolites from the body
**kidneys excrete most drugs; lungs = primary route of excretion for gaseous substances; bile in GI tract
Where should adverse reactions to medications be reported
MEDWATCH or a national database
MedWatch
safety information and voluntary adverse events reporting program, sponsored by the U.S. Food and Drug Administration, which also provides up-to-date information about medication errors and potential or actually medical product problems and errors
For a drug to be an adverse effect it must
life threatening action
requires intervention to prevent death/impairment
leads to death/hospitalization/disability/congenital deformity
What are the 3 red drugs
Insulin (need 2 licensed prof to dbl check)
Any anticoagulants
IV narcotics
What are CPOEs and what do they allow
Computer-generated pharmacy order system
allows prescriber to enter medication sorters in a standard format + guide the prescriber in complete, accurate, and appropriate ordering
**prevents guess handwritten orders
stat order
single order, but carried out immediately
What is needed on the medication order
Patient name
Date and time order is written
Name of drug
Dosage of the drug
Route by which the drug is to administered
Frequency of administration of the drug
Signature of the person writing the order
What are the terms used to describe route administration
Oral
Parenteral (SubQ,Intramuscular, Intradermal)
Topical
Pulmonary