Medication Administration 1 Flashcards
What is medication?
A substance used in prevention of disease, diagnosis, relief of a symptom, treatment or cure of health alterations
What are 7 responsibilities a nurse has related to medication?
- Interpret
- Transcribe
- Prepare
- Administer
- Teach
- Document
- Evaluate patients response to meds
What would a nurse TEACH a patient about medication?
- Side effects
- Purpose
- Directions
- Frequency
Can student nurses transcribe medication?
NO
What does the chemical name of a medication mean?
It is the first name given and describes chemical components/molecular structure
What does the generic medication name mean?
It is a shortened chemical name given by the first manufacturer
What does the trade/brand name mean?
Name given by manufacturer for marketing
What generally is the reason for drug classification?
Indicates the effects of medication on the body, the symptoms it relieves or the desired effects
What are some examples of drug classifications?
- Beta blockers
- ACE inhibitors
- Anticoagulants
Is it possible for a drug to have more than one classification
Yes
What two classifications does Tylenol have?
- Analgesic
- Antipyretic
The drug form determines ______
it’s route of administration
What influences a medications absorption and metabolism?
it’s composition
What is pharmacokinetics?
The study of how medications enter the body, reach their site of action and exit the body
What are the 4 steps of pharmacokinetics?
- Absorption
- Distribution
- Metabolism
- Excretion
Each step in pharmacokinetics is influenced by what two things?
- Route of administration
- Functioning of body organs
What does absorption mean in pharmacokinetics?
- Movement of medication from where it entered body to bloodstream
What are 5 factors that influence absorption of a medication?
- Route of administration
- Ability of medication to dissolve
- Blood flow to site of administration
- Body Surface area
- Lipid solubility
Why would lipid solubility affect absorption of medication?
High lipid solubility absorbs quicker because a cell membrane has a lipid layer
Which absorbs faster: acidic or alkaline?
Acidic
What does distribution mean in pharmacokinetics?
Transport of medication via bloodstream to site of drug action
What are two factors that influence drug distribution?
- Properties of medication
- Physiology
What are some reasons physiology could play a role in drug distribution throughout the body
- Circulation
- Membrane permeability (ex. blood brain barrier, only lipids can pass through)
- Protein binding
- Amount of medication
What can lower albumin in blood mean for medication distribution?
Less= more free medication, which can lead to toxicity
What is the first pass effect?
The concentration of a drug is greatly reduced before it reaches the systemic circulation
( the first pass through the liver greatly affects bioavailability of the drug)
What is bioavailability
the proportion of a drug or other substance that enters the circulation when introduced into the body and so is able to have an active effect.
What is metabolism in regards to pharmacokinetics
The breakdown of medication into an inactive/less active form
How does metabolism occur?
As enzymes detoxify, degrade and remove biologically active chemicals
Where can biotransformation occur?
Mostly in liver
Can occur in lungs, kidneys, blood and intestines
If kidneys aren’t functioning, what can there be a risk of when taking medication?
Toxicity