Medical Parasitology Flashcards
7 risk factors for parasitic disease
Domicile/traveler in endemic zones
Consumption of raw or incompletely cooked food
Barefoot exposure to soil
Exposure to fresh water
Blood to blood exposures (blood transfusions, IV drug use)
Sexual activity
Immunocompromised
Type of host that harbors adult parasite; is where reproduction takes place
Definitive host
Type of host that harbors larval forms; is where asexual reproduction takes place but adults do not develop
Intermediate hosts
Infection passed from an animal to a human
Zoonotic
A zoonotic infection describes this
Passed from animal to a human
2 types of vectors
Mechanical or biological
Are protozoans or metazoans single-celled organisms?
Protozoans
Are protozoans or metazoans multicellular organisms?
Metazoans
4 relevant phyla of protozoans
Amoebozoa
Flagellates
Ciliates
Apicomplexans (aka Sporozoans or Coccidians)
Protozoan or Metazoan:
Amoebozoa (include Loboseans and Heteroloboseans)
Protozoan
Protozoan or Metazoan:
Flagellates (include Diplomonads, Parabasalids, and Kinetoplastids)
Protozoan
Protozoan or Metazoan:
Ciliates (Ciliophora)
Protozoan
Protozoan or Metazoan:
Apicomplexans (aka Sporozoans or Coccidians)
Protozoan
Protozoan or Metazoan:
Nemathelminths (roundworms)
Metazoan
Protozoan or Metazoan:
Platyhelmintes (flatworms)
Metazoan
Other names for roundworms
Nematodes, Nemathelminthes
Other name for flatworms
Platyhelmintes
2 subdivisions of Platyhelminthes (flatworms)
Cestodes (tapeworms) and Trematodes (Flukes)
Other name for cestodes
Tapeworms
Other name for trematodes
Flukes
Other name for tapeworms
Cestodes
Other name for Flukes
Trematodes
Other name for flatworms
Platyhelminthes
Protozoans typically require a large amount of this
Moisture
Majority of protozoans are _______
free-living
Found in marine, fresh water and terrestrial habitats
Protozoans are an important part of the food chain because of this function
Are essential decomposers
Do protozoans have a cell wall?
No
Are protozoans eukaryotic or prokaryotic?
Eukaryotic
Do protozoans have chloroplasts?
No
Do protozoans have structures for movement?
Yes
Cilia, flagella, or pseudopodia
Protozoan vegetative or feeding form
Trophozoite
Protozoan resting form
Cyst
Trophozoite is this form of protozoan
Vegetative or feeding form
Cyst is this form of protozoan
Resting form
Most common mode of protozoan reproduction
Binary fission
Process where the nucleus divides numerous times then the cell produces numerous single-celled organisms
Many protozoans replicate via this mechanism
Schizogony
Schizogony is a method of reproduction involving many fissions, and is used by this type of microorganism
Protozoans
3 mechanisms of entry for protozoan infections
Ingestion
Sexual transmission
Via arthropods
Protozoan pathogenesis involves these 2 main effects
Tissue damage
Release of toxins
Amoebozoa move by this
Pseudopodia
Amoebozoa possess this many nuclei per cell
1-2
Amoebozoa replicate by this
binary fission
Amoebozoa ingest by this
Endocytosis
2 groups of Amoebozoa
Loboseans and Heteroloboseans
Flexible body form of Amoebozoa
Ameboid
Group of Amoebozoa that extend and retract pseudopodia
Engulf food particles by phagocytosis
Loboseans
Group of Amoebozoa that are ameboid (flexible body form), also form flagellated cells
Heteroloboseans
Do flagellated protists have mitochondria?
No
How do flagellated protists reproduce?
Asexually
Flagellated protist that typically have 2 nuclei and reside in stagnant water low in O2 or in anaerobic conditions inside hosts
Diplomonads
Flagellated protists that live within the host
Some cause disease; a few also reproduce sexually
Hydrogenosome produces some ATP while generating hydrogen
Parabasalids
Flagellated protist that have at least one flagellum
Distinctive complex mass of DNA in their large single mitochondrion
Kinetoplastids
Protozoans that move by cilia coating the cell
Form cysts under adverse conditions
Ciliates (Ciliophora)
Ciliates possess this many nuclei per cell
1-2
Ciliates replicate via this
Binary fission
Ciliates ingest nutrients through this
Cytostome
Ciliates excrete waste through this
Anal pore
Protozoans that ingest nutrients through cytostome and excrete waste through anal pore
Ciliates (Ciliophora)
Protozoans that are intracellular parasites
Apical complex at one end; helps penetrate membrane of host cells
Many have complex life cycles, alternate between sexual and asexual forms
Apicocomplexans (Sporozoans or Coccidians)
Apicomplexans have this which helps penetrate membrane of host cells
Apical complex at one end
Metazoans that multicellular, complex organisms
Have rudimentary nervous and digestive systems
Have outer covering (cuticle) that is shed at the beginning of each developmental stage (molt)
Use sexual reproduction (egg laying); males and females may be separate individuals or in the same organism (hermaphroditic)
Are highly allergenic
Helminths
Helminths have this outer covering that is shed at the beginning of each developmental stage (molt)
Cuticle
What is a cuticle?
Outer covering that is shed at the beginning of each developmental stage (molt) in helminths
Reproduction mechanism of helminths
Sexual reproduction
Parasitic helminths that are male and female
Nematodes aka roundworms
Parasitic helminths that are hermaphroditic
Cestodes aka tapeworms
Also often trematodes aka flukes
4 mechanisms of helminth entry into the body
By intermediate host
Fecal-oral
Skin penetration
Injection by blood-sucking insect
Helminth with long, cylindrical, narrow bodies
Exist as separate sexes
Have digestive tracts
Transmission, either the egg or the larvae can be infectious unit
Nematode
Shape of nematodes
Long, cylindrical, narrow bodies
Roundworms
Helminths with flattened body surfaces
Are hermaphroditic
Possess or lack digestive tracts
Possess hooks and/or suckers for attaching to tissues
Platyhelminths (flatworms)
Shape of platyhelminths
Flattened body surfaces
(Flatworms)
Sexes of nematodes
Exist as separate sexes
Sexes of platyhelminths
Hermaphroditic (except for blood flukes)
Platyhelminths that possess digestive tracts
Flukes / Trematodes
Platyhelminths that lack digestive tracts
Cestodes (tapeworms)
Platyhelminths that possess hooks for attaching to tissues
Cestodes (tapeworms)
Platyhelminths that possess suckers for attaching to tissues
Cestodes (tapeworms) and Trematodes (flukes)
Humans are this type of host for intestinal cestodes and tapeworms
Definitive hosts
Become infected by ingesting larvae; adult worms live in the intestine
Humans are this type of host for tissue cestodes
Intermediate hosts
Become infected by ingesting eggs; larvae live in tissues
Helminths with bilateral symmetry and leaf-shaped
Suckers to hold as well as suck fluid
Most are hermaphroditic
Snail can be intermediate host
Trematodes
Shape of trematodes
Bilateral symmetry and leaf-shaped
Common intermediate host for trematodes
Snail
Term for microbes that live on/in us
Faithful to one host
Parasitic
Term for microbes that feed on us intermittently
Important as vectors
Predatory
Term for microbes that physically spread germs
Polluting