Medical Oncology II Flashcards
Performance Status Tool ECOG
Fully active, able to carry on all pre-disease performance w/o restriction
ECOG 0
Performance Status Tool ECOG
Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature
ECOG 1
Performance Status Tool ECOG
Ambulatory and capable of selfcare but unable to carry out any work activities. Up and about more than 50% of waking hours.
ECOG 2
Performance Status Tool ECOG
Capable of only limited selfcare, confined to bed or chair more than 50% of waking hours
ECOG 3
Performance Status Tool ECOG
Completely disabled. Cannot carry on selfcare. Totally confined to bed or chair.
ECOG 4
Performance Status Tool ECOG
Dead
ECOG 5
Common side effects of chemo are?
n/v
diarrhea/constipation
mouth sores
hair loss
cytopenias
Side effects of radiation include?
localized erythema
redness
skin irritation
internal inflammation (esophagitis, colitis, pneumonitis)
hair loss
cytopenias
Common inpatient cancer diagnosis:
Lung > if small cell, likely needs what?
inpatient chemo & lab monitoring
Common inpatient cancer diagnosis:
Lymphomas > Primary CNS or diffuse large B-cell, likely needs what?
inpatient chemo & lab monitoring
Common inpatient cancer diagnosis:
Brain > likely needs what?
surgery vs non-surgery, needs radiation c/s
Common inpatient cancer diagnosis:
GI/pancreatic/breast/HCC/Head+Neck > get the workup then likely what?
doesn’t need inpatient chemo and can follow up outpt
When giving chemo monitor what?
administration and time of treatment
adverse effects
lab monitoring
Chemo side effects:
Ifosfamide can cause?
neurotoxicity (twitching, lethargy)
Chemo side effects:
Cytarabine can cause?
cerebellar toxicity (monitor handwriting coordination)
Chemo side effects:
5-FU can cause?
coronary vasospasm
Immunotherapy related adverse effects?
Pneumonitis
Colitis
Dermatitis (Steven-Johnson’s)
Neurologic (Myasthenia gravis, transverse myelitis)
Complications of treatment can include?
N/V
Diarrhea/constipation
Cytopenias, FVO, AKI, Transaminitis
Failure to thrive - G-tube placement, PT/OT/RD c/s
Fever infection
Complications of Disease
Progression of disease causing:
Brain mets > ?
New HA, AMS seizures, Stroke like symptoms
Complications of Disease
Progression of disease causing:
Bony mets > ?
ACUTE pain, fractures
Complications of Disease
Progression of disease causing:
Worsening mets > ?
SOB
gastric outlet obstruction
hemoptysis
GIB
malignant bowel obstructions
hyperbilirubinemia
obstructive uropathy > need for ERCPs, biliary drains, stents etc
Neutropenia is ANC of what?
<1500
Severe Neutropenia is ANC of what?
< 500
Full infectious workup for neutropenic fevers includes?
BC
UC
CXR/other imaging
RVP/COVID
wound cultures + empiric spectrum abx
