Medial Temporal Lobe Flashcards

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1
Q

Why is MTL considered the “Hub of Hubs”?

A

Highly interactive and well placed for integrating multiple brain regions, as well as coordinating learning and retrieval from the neocortex.

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2
Q

Hippocampus in the MTL is believed to be a map for what?

A

Spacial localization

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3
Q

What else is the Hippocampus associated with besides Spacial Localization?

A

Olfaction

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4
Q

Due to the Hippocampus’ location in the MTL it is ideally suited to _______

A

combine information between the neocortex and emotional (limbic) areas and to “bind” that information into memory traces.

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5
Q

The MTL is strategically located next to the inferior temporal lobe to take in what information?

A

high level, conscious visual information

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6
Q

What is the auditory cortex relationship with the MTL

A

auditory information may be fed into an episodic learning system of which the MTL is responsible.

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7
Q

Describe process of recall of episodic memory in MTL

A

Retrieval occurs when a conscious cue triggers the MTL, which in turn activates the entire neocortical ensemble associated with it.

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8
Q

The recovery of experiences always depends on what?

A

The Hippocampus

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9
Q

medial temporal lobe damage

affects all four operations of memory which are:

A

Encoding
Storage
Consolidation
Retrieval

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10
Q

In studies on recall of words and pictures, this area was active in the task along with the MTL

A

Words: Left prefrontal cortex activated
Pictures: Right prefrontal cortex activated

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11
Q

The neural circuits that initiate these types of implicit memory are independent of the MTL system

A

habit,
motor skill,
conditioned learning

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12
Q

MTL activation during Non-REM sleep

A

relative deactivation compared to resting wakefulness

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13
Q

MTL presentation in Schizophrenia

A

reductions in gray matter volume including in the hippocampus and amygdala

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14
Q

Changes in MTL differentiate these two mental disorders:

A

Schizophrenia and Bipolar Disorder

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