Med Review Notes Flashcards
Indication for risperidone in elderly ….
maximum duration ….
Aggression in Alzheimers disease - where there is a risk of harm to pt or others
6weeks
Nitrates are used in treatment of….
work by…
angina
vasodilators - reduce venous return which reduces LV work
Duration of action of sublingual GTN
20-30 mins
advantage and disadvantages of transdermal nitrate preparations
- tolerance may develop
- duration of effect prolonged
advantage of isosorbide dinitrate over GTN
stable for longer - suitable for less frequent use
activity of isosorbide dinitrate is dependent on what pt factor
productions of the active metabolite isosorbide mononitrate
how to maintain effectiveness of transdermal nitrates
reduce blood nitrate levels for 4-12 hours daily or tolerance will develop
how to maintain effectiveness of MR isosorbide dinitrate and conventional release isosorbide mononitrate
second dose 8 hours after first - not 12 hours. Or tolerance may develop
s/e of nitrates (4)
tachycardia
throbbing headache
postural hypotention
dizziness
GTN tabs discarded …. after opening
8 weeks