Med Review Notes Flashcards

1
Q

Indication for risperidone in elderly ….

maximum duration ….

A

Aggression in Alzheimers disease - where there is a risk of harm to pt or others
6weeks

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2
Q

Nitrates are used in treatment of….

work by…

A

angina

vasodilators - reduce venous return which reduces LV work

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3
Q

Duration of action of sublingual GTN

A

20-30 mins

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4
Q

advantage and disadvantages of transdermal nitrate preparations

A
  • tolerance may develop

- duration of effect prolonged

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5
Q

advantage of isosorbide dinitrate over GTN

A

stable for longer - suitable for less frequent use

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6
Q

activity of isosorbide dinitrate is dependent on what pt factor

A

productions of the active metabolite isosorbide mononitrate

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7
Q

how to maintain effectiveness of transdermal nitrates

A

reduce blood nitrate levels for 4-12 hours daily or tolerance will develop

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8
Q

how to maintain effectiveness of MR isosorbide dinitrate and conventional release isosorbide mononitrate

A

second dose 8 hours after first - not 12 hours. Or tolerance may develop

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9
Q

s/e of nitrates (4)

A

tachycardia
throbbing headache
postural hypotention
dizziness

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10
Q

GTN tabs discarded …. after opening

A

8 weeks

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