Med EMRG Exam 1 Flashcards

1
Q
A

Biot’s: Irregular pattern (↑ ICP).

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2
Q
A

Kussmaul’s: Deep & labored (DKA).

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3
Q
A

Apneustic: Gasping inspiration w/ long pauses

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4
Q
A

Cheyne-Stokes: Waxing & waning w/ apneic periods (↑ ICP).

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5
Q
A

Central neurogenic ventilation

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6
Q

Shortened Nrv. pathway involved in a reflex action is:
Speed of reflex ultimately allows for

A

= reflex arc
= quick responses, reducing the seriousness of injury. Other reflexes help stabilize the body if it stands in one position for a length of time.

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7
Q

Reflex arc:
Acquires impulse speed via:

A

= sensory ascending Nrv. pathway involved in reflex action
= Short pathway

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8
Q

1 Cause of Cardiogenic shock

A

Heart Attack / MI

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9
Q

CAD):
CVD):

A

= Coronary Artery disease: disease affecting coronary vessels
= Cardiovascular disease: affecting heart, peripheral blood vessels, or both

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10
Q

ipsilateral:
Contralateral:

A

= same side
= opposite side

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11
Q

PVC) Bigeminy:
Trigeminy
Quadgeminy

A

= 2rd beat uni/PVC regularly “boom PVC” (1:1 pattern)
= 3rd beat is uni/PVC regularly “boom boom PVC)
= 4rd beat is uni/PVC regularly “boom boom boom PVC” 2-3x

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12
Q

Lung perfusion depends on 3 conditions:

A

= Adequate blood vol/, Intact pulmonary capillaries, Efficient pumping of blood by the heart

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13
Q

O2 gradient provides the driving force in:
Larger difference between concentration of oxygen in the alveoli & capillaries:

A

= moving oxygen into the capillaries (diffusion)
= the greater the diffusion of oxygen into the bloodstream

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14
Q

Fixed pacer:

Demand pacer:

A

=NONDEMAND PACER Fires continuously at preset rate, regardless of heart’s electrical activity, TC pacing nondemand
= non-fixed, Sensing device; fires only when natural HR drops

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15
Q

Atrial pacer:
Definers:
Treatment:

A

= paces only in atrium
=Atrial line w/ P wave following
= (ask PT for pacemaker card) Magnet donut, TCP, bradyC & asystole as any other PT

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16
Q

Ventricular pacer:
Definers:
Treatment:

A

= paces only in ventricle
= line before QRS complex & Wide QRS
= (ask PT for pacemaker card) Magnet donut, TCP, bradyC & asystole as any other PT

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17
Q

AV Sequential pacer:
Definers:
Treatment:

A

= paces in atrium & ventricle
= line before P wave & QRS, wide QRS
= (ask PT for pacemaker card) Magnet donut, TCP, bradyC & asystole as any other PT

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18
Q

Failure to capture pacer:
Definers:
Treatment:

A

= not shocking/pacing when supposed to
= Pacer Spikes are not before each beat
= (ask PT for pacemaker card) Magnet donut, TCP, bradyC & asystole as any other PT

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19
Q

1 cause of death when having a MI

A

is from a lethal dysarrhythmia

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20
Q
  1. Tonic Phase:
  2. Hypertonic Phase:
  3. Clonic Phase:
  4. Postictal:
  5. Aura:
A

1= “Tensed” contraction of muscles
2= Muscular rigidity w/ hyperextension of back
3= “Crazy” Rhythmic jerking motion of EXTRMS, SC-muscles & diaphragm temporarily paralyzed, can cause skeletal injuries, Severe acidosis from excessive ATP waste (Co2, H2o, temp)
4= State of confusion & fatigue after clonic phase; Brain restarting & exhausted from activity
5= sensation that sometimes precedes a seizure: Smell, taste, sound, Commonly metallic taste, can be any sense

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21
Q

2 general mechanisms for AMS:

A

Structural Lesions & Toxic-metabolic states
Other general causes of AMS: Drugs, Cardiovascular problems, Respiratory problems, Infections

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22
Q

3 Is of cardiac) Ischemia:
“Infarct” Injury:
Infarction:

A

= Ischemia: ST depres/, Hyperacute T waves>5chest avf >10 precordial
= “Infarct” Injury: ST elevation 50%,
= Infarction: old MI; >25% Q or QRS >1SB

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23
Q

an atmospheric Pressure is how many ft/yards:
Pluera fluid & -neg pressure:
With what condition “can get air in but not out”
which is active & passive w/ I:E

A

= 33ft / 11yards
= ~⅓ of keeping negative pressure 10-15mLs
= COPD
= inhalation active & exhalation passive

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24
Q

What are the two main causes of AMS?

A

= Structural lesions & toxic-metabolic states.

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25
How does arterial PCO2 increase affect blood pH? How does carbon dioxide leave the blood:
= decreases blood pH by increasing the concentration of hydrogen ions = CO2 moves out of the blood into alveoli due to the concentration gradient.
26
: What structure produces the majority of CSF?
Choroid plexus
27
A patient calls 911 today because they are having some trouble breathing. The patient states for the last couple of days, they have had some on and off again chest pain with dyspnea, and today they started to notice some swelling in their ankles. Based off this history, you would suspect
The patient started with left ventricular failure that is now causing the right ventricle to fail as well
28
A patient is unable to move their eyes downward and medially. What cranial nerve is dysfunctional?
Cranial Nerve IV
29
A patient stated they were diagnosed with a disease of the lungs that dealt with the direct destruction of the alveoli. You would identify this as
Emphysema
30
L-ventricular dysfunction S/S:
Dyspnea, Rales, Tachypnea "Left Lungs"
31
R-ventricular dysfunction would most likely present with:
Ascites, JVD, Peripheral edema "Right Tight (skin w/ edema)"
32
Pick’s disease: S/S:
= permanent form of dementia; tends to affect only certain areas of brain & have abnormal substances (called Pick bodies & cells) inside nerve cells in the damaged areas of brain. These Pick bodies contain an abnormal form of a protein called tau. The exact cause of the disease is unknown = tend to behave the wrong way in different social settings. The changes in behavior continue to get worse and are often one of the most disturbing symptoms of the disease. Some patients will have more prominent difficulty with decision making, complex tasks, or language (trouble finding or understanding words or writing). There is no specific treatment for Pick’s disease.
33
A pulmonary disease that is created by the pulmonary tissue producing excessive amount of mucus is:
Chronic Bronchitis
34
Abdominal Aortic Aneurysm (AAA): S/S: Ligament:
= Bulging of abdominal aorta. = Pulsatile abdominal mass, back/ABDMN pain, hypoBP if ruptured = Ligamentum arteriosum
35
Abdominal situs Inversus=
Spleen & Liver flipped but H normal
36
Absence Seizure (Petit Mal Seizure): Seizure characteristics:
Generalized, nonconvulsive seizure, w/ brief LOC (blank stare), motionless, unresponsive (can become grand mal & rarely has aura) = “Brain pauses then resumes”, 10-30secs duration, Commonly 3-5 secs only, PT able to resume normal activity immediately after seizure (Glutamate kicks in & shuts down)
37
Adrenal Gland Disorders:
= Hyperadrenalism (Cushing’s Syndrome) & Hypoadrenalism (Addison’s Disease)
38
adventitious lung sounds:
= crackles/rales, wheezes, rhonchi, stridor, & pleural rubs
39
Huntington’s chorea/ Huntington’s disease) Cause: 2 Forms & most common: Adult onset: Early onset: S/S:
= genetic defect in chromosome #4. = (Adult & Early onset) Adult onset is most common = develop symptoms in their mid-30s & 40s = begins in childhood or adolescence. = can resembleParkinson’s disease w/ rigidity, slow/unusual Mnt, tremor, behavioral changes (e.g., antisocial behaviors, irritability, and hallucinations), , & dementia (e.g., loss of memory and judgment). There is no treatment
40
Alvelore pores: Dust cells: Type 2 cells:
= “back doors” produces surfactant = macrophages of the lungs = are the last cells dev in ertro & produces surfactant & reason why babys have issues w/ BVM Fetal lung fluid
41
Alzheimer’s Disease: Brain differences: Effects of brain & S/S:
= Subtle onset of memory loss followed slowly progressive dementia over several years = diffuse atrophy of cerebral cortex & enlarged ventricles =Presence of abnormal deposits of proteins Amyloid plaques & tau tangles |Memory loss, Shuffling gait, Muscle stiffness, Aphasia
42
Amyotrophic lateral sclerosis (ALS) aka Characterized by:
= Lou Gehrig’s disease, progressive degeneration of specific nerve cells that control voluntary mnt. = weakness, loss of motor control, dysphasia,& cramping, & eventually weakens the diaphragm
43
Amyotrophic: Lateral Sclerosis:
= shrinkage of musculature = loss of nerve fibers in lateral columns of WM of SC (No cure & poor prognosis – Death w/in 2-5Yrs)
44
An unconscious patient was pulled out of his enclosed garage after he attempted to kill himself with carbon monoxide. Your partner has attached the CO-Oximeter and it shows a reading a 50% carboxyhemoglobin. You quickly identify this as:
Severe CO poisoning
45
Anabolism: Catabolism:
=building processes within a cell (Uses Energy) = Breakdown processes w/in cell (produces energy)
46
ANP Atrial natriuretic peptide:
made, stored, & released by atrial M> cells in response to atrial distension & Sympathetic stim & counters RAAS system, Decreases afterload pressure
47
Anterior cord injury Results from: S/S:
= bony fragments or pressure compressing arteries that profuse anterior SC, Usually w/ severe extension-flexion injury = Loss of motor function, sensation to pain, light touch & temperature below the injury site
48
Antipyretic needed when temp >
only if fever is >101F)
49
Any expanding lesion within the cranium results in
a increase in intracranial pressure
50
Aortic aneurysm: S/Ss:
= weakness aorta wall can rupture, Dissecting aneurysm occurs when inner layers of aorta become separated = Very sudden chest pain & full force, “Ripping/Tearing ” in nature, Pulse & BP deficit
51
ARDS Also known as
= “Noncardiogenic Pulmonary Edema”
52
Arteriosclerosis is
hardening of the blood vessels “AR h-AR-d”
53
What is Acute Coronary syndrome?
A spectrum of conditions caused by sudden reduced blood flow to the heart. Includes unstable angina, NSTEMI, & STEMI.
54
ETCO changes w/ asthma: Status asthmaticus:
= worsens ETCO rises up again to normal as worsens, if worsens beyond rise then hypercapnic = Resp failure imminent, Agressive w/ meds, Might give dex
55
Asthma phase 1 Asthma phase 2
= Bronchospasm w/in mins, reversible w/ bronchodilators. = Inflammatory response 6-8 hrs later, steroids required.
56
NS Glial cells) Astrocytes: Microglia: Oligodendrocytes: Schwann Cells:
= Regulate blood-brain barrier & nutrient supply = Immune defense in CNS. = Myelinate CNS axons. = Myelinate PNS axons.
57
Atherosclerosis is
buildup of plaque in-between arteries' media & intima “40% block = 60% of blood getting through” "ATh F-AT"
58
Atherosclerosis:
= Type of arteriosclerosis involving plaque buildup (fat, cholesterol, etc.) narrowing arteries. "fAT AThero"
59
Atrial appendages:
(abnormal heart birth defect) pockets that form clots on either atrium from uterine dev/,
60
What? Manufactured, stored, & released by Atrial M. cells in response to such things as atrial distention and sympathetic stimulation.
Atrial Natriuretic Peptide (ANP)
61
BAAM=
Beck Airway Airflow Monitor→ high pitch on inhale
62
Back Pain & Nontraumatic Spinal Disorders
Low back pain Disk injury Cauda Equine Syndrome
63
Baroreceptors) Fn: A&P:
= receptors that monitor blood pressure = Great vessels recept/ Gives feedback to brain > Sympathetic NS Activation, AArch & carotid arteries> feedback to medulla >SNS
64
Be able to explain the hypercarbic and hypoxic drives and how do they differ
carbic=too much CO2 so initiates from high PACO2 Oxic= not enough oxy so initiates from low PAO2
65
aortic dissection is: Fixation points: S/S:
= Tearing or arterial fixation points = Ligamentum Arteriosum Aorta & = Pulsus deficit R-hand pink left cold blue, Severe tearing chest pain w/ ripping pain radiating into back, Hypotension, Tachycardia
66
Benign Early Repolarization (BER) ECG changes:
Widespread concave ST elevation limited to precordial leads (usually V2-V5) Absence of PR depression Prominent T waves Characteristic “fish-hook” appearance (often best in lead V4)
67
Pericarditis: Usually presents w/: S/S:
= inflammation of the pericardium, the sac structure w/ 2 layers of tissue that surrounds the heart (Pericardial friction rub) = concave STE, PR Depression in multiple leads Spodick’s Sign, rub @ ERb's point = Paroxysmal nocturnal dyspnea (PND), Hx of sick,
68
Benzodiazepine Effect on Seizures) Increased GABA activity: Reduced Glutamate Activity: Ion Channel Modulation:
= ↑ Cl- influx → Hyperpolarization Prevents APs from firing = ↓ Na+ influx → Less Depolarization Decreases excitability = ↓ Ca2+/Na+ currents Prevents neuronal overfiring
69
Down-regulation: Excitability from recepetors:
= Med,hormone,ect to a target cell receptor causes # of available receptors to decrease = of the receptors results in a decreased responsiveness of the target cell to the medication or hormone as the number of available active receptors decreases.
70
Blood-Brain Barrier) built so: Prevents & Protects:
= CNS capillary walls thicker, more complete, not as permeable as elsewhere in body. = Doesn't permit interstitial flow of proteins & materials as freely as normal capillaries, Protects w/ need lipid loving to get through, anything that can get through can cause damage
71
BNP Brain Natriuretic peptide:
secreted by ventricles in response to stress to excessive stretching of myocytes & Counter RAAS
72
Brain Abscess:
= A collection of pus & inflammation localized in the brain.
73
Brain Herniation) def/: Initial stages: Late Stage: S/S: Para/Sympathetic Nervous System affect:
= Trauma causes swelling inside skull = blood & CSF are compressed out. = Increasing ICP forces brain out foramen magnum (can cause cushings) = 1 pupil sluggish or dilated, or unequal (anisocoria), Decorticate or Decerebrate posturing, Abnorm/ Resp/s, Severe altered/LOC, Weakness/Paralysis, Projectile vomiting = Cuts off PSNS response thus + SNS (SNS thoracic lumbar) (PSNS cranial sacral)
74
Brain Injury) 1 S/S: 2 Treatment of Brain Herniation: 3 Vent/ing Brain Herniation: 4 Do not let PT become: 5 Note with ETCO2 & ICP:
1= AMS, Alterations in personality, Amnesia, Cushing's triad 2= Maintain ETCO2 between 30-40, Vent/ at upper end of norm/, Admin IV fluids for SBP 90-100, 3= Adults: No more 20 per/min, Children: No more 30per/min Infants: No more 35 per/min 4= hypoxic or hypovolemic 5= Norm ETCO2 35-45 but controlled hypervent/ 30-40 (if overoxygenate can actually decrease amount going to brain)
75
Mid brain) 1 Hypothalamus: 2 Thalamus:
= “homeostasis” Endocrine Fn, N/V reflex, hunger, thirst, kidney Fn, body temps, emotions = Establishes & maintains consciousness; pathways for optic & olfactory nerves
76
Pons: Medulla Oblongata:
= Communication interchange between CNS components = Respiratory center, cardiac center, vasomotor center.
77
Capography wave forms
78
Carbon monoxide poisioning color:
cherry (cherry is usually dead)
79
Carbon Monoxide Poisoning lethal bc: CO hemoglobin affinity
= Odorless, tasteless, & colorless gas = higher affinity to Hemoglobin than that of O2
80
Cauda Equina Syndrome) def: Usually caused by: S/S:
= Nerve roots @ lower end of SC are compressed = herniated disc, tumor or infection = Loss of bowel & bladder control – Saddle anesthesia
81
Central Cord Syndrome) Usually results from: Considered what type of injury: S/S: More commonly seen in patients:
= hyperextension of the cervical spine = incomplete cord injury = motor loss/weakness to upper EXTRMs & bladder Fn loss = >50 years of age &/or w/ arthritis
82
Central Pain Syndrome: Cause by: S/S:
= Neurological condition that results from damage or dysfunction to the brain, brainstem, & SC = stroke, MS, tumors, trauma, Parkinson’s = Burning, Tingling, Loss of sensation (Not fatal, but causes disabling chronic pain)
83
Central pain syndrome: Characterized by: Occurs in PTs who have had:
= condition from damage/injury to brain, brainstem, or SC dev/ Wks, Mns, or Yrs after injury to CNS = intense, steady pain described as burning, aching, tingling, or a “pins and needles” sensation = strokes, multiple sclerosis, limb amputations, or SC injuries. (Pain meds generally provide no relief so they rely on sedation & other methods to keep CNS free from stress)
84
Cerebellum Fn: location: Brainstem + Cerebellum:
= Coordinates: Fine Motor, Posture, Equilibrium, M. tone, CN8 = Located in the posterior fossa = Hindbrain (Contains 2 hemispheres)
85
Both brain & SC bathed in what acting as cushion & vol:
= CSF~150mL; watery, clear fluid that acts as cushion
86
Cerebrum) lobes
= occipital, temporal, parietal, frontal
87
Cerebrum) 1 Frontal Lobe 2 Broca’s Area 3 Central Sulcus/Fissure 4 Parietal Lobe 5 Postcentral Gyrus 6 Precentral Gyrus 7 Occipital Lobe 8 Temporal Lobe “Hearing & Language” 9 Cerebellum “Balance & Coordination” fine motors 10 Pons 11 Medulla Oblongata 12 Corpus callousum
1= “Personality” 2= Broca’s Area 3= Central Sulcus/Fissure 4= “Sensory” Wernicke’s Area “speech comprehension” 5= Primary sensory cortex 6= Primary motor cortex 7= “Vision” 8= “Hearing & Language” 9= “Balance & Coordination” fine motors 10= Pons 11= Medulla Oblongata 12= Corpus callousum
88
chemoreceptors=
in the carotid bodies and in the arch of the aorta. These chemoreceptors are stimulated by decreased PaO2, increased PaCO2, and decreased pH
89
S3 inditcates: S4 indicates:
= CHF maybe or begining stages = in CHF (Aortic, Pulmonic, Erb’s point (3rd ICS), Tricuspid)
90
Chordae Tendineae: Heart regurgitation:
= connect valves’ leaflets to papillary-M.s to prevent valves from prolapsing into atria & allowing backflow during ventricle contraction = papillary not working &/or valve doesn't correctly opens so prolapse
91
Choroid plexus) located & Fn: CSF flow starts at 1: CSF through surrounding 2: CSF returned to3: CSF dumped off 4:
=in brain ventricles gen/s CSF in largest 2-4 ventricles = lateral ventricles to 3rd & 4th ventricle = through subarachnoid space surrounding brain & SC = venous circulation through arachnoid granulations = dural sinuses of brain & through spinal arachnoid space to arachnoid villi found @ end of SC (spinal cistern)
92
Chrontropy: Inotropy: Dromotropy:
= HR, + tropic +HR vice versa = Contraction force = Speed of impulse transmission, usually goes w/ Inotropy “Drone robot electricity”
93
Cincinnati Prehospital Stroke Scale (CPSS)
= 1 + 77% ac & All 3 93-97% accurate (FAST) = Face Arm Speech Time (LKN) Facial Droop: – Have the patient smile or show their teeth Arm Drift: Have the patient extend their arms straight out, with palms up, and hold them there for 10 seconds. Speech: PT say “you can’t teach an old dog new tricks” (1 sentence, easily relay 6-7 words)
94
(Electrolytes affects) Cl Na K Ca Mg
= Cl picks up Co2 (shift) to keep neutrality = depolarizing myocardium = depolarization & majority myocardial contractile = influences repolarizations = regulates contractility & rhythm
95
Clubbing fingernails:
= “finger clubs” distal phalanx of each finger is rounded and bulbous. The proximal nail feels spongy. This is caused by the chronic hypoxia found in cardiopulmonary diseases and lung cancer.
96
Clubbing fingernails:
= “finger clubs” distal phalanx of each finger is rounded and bulbous. The proximal nail feels spongy. This is caused by the chronic hypoxia found in cardiopulmonary diseases and lung cancer.
97
CN 10:
= vagus “wondering” parasympathetic F.s: HR, digestion, & RR & also provides sensory info from throat & voice box.
98
CN 2,3,4,6
Pupil correlates w/ L. of injury EX right pupil blown is right brain trauma
99
CNS) The Brain: Makes up ~ what% of cranial vault Cranium's 3 major structures
= 80% = Cerebrum, Cerebellum, Brainstem
100
Common abnormal respiratory patterns? =
= Cheyne-Stokes, Biot's, Kussmaul's, Apneustic, Central neurogenic
101
Communication or the connecting of two or more vessels is known as:
= Anastomosis
102
Congestive Heart Failure (CHF):
= Weakened heart unable to efficiently pump blood from L-ventricle = May be acute or chronic, May occur suddenly, during an MI, Flash Pulmonary Edema
103
Contractility:
= ability of CM. cells to contract, or shorten (Actin Myosin) Calcium & +Beta1 effects
104
W/ COPD, need to more careful in case of
= bleps in lung & can rupture
105
Cor Pulmonale:
= R ventricle & maybe Atrium hypertrophy from fluid overload
106
Cranial nerve location mnemonic: Nerve locations:
= "Sexy EMTs Play Erotic Jokes, Exciting Their Erotic Lover's Asshole Stimulating Them." = Sniffer- smells (Olfactory) = Eyes - Eyesight (Optic) = Pupils - Pupils & eye movement (Oculomotor) = Eyes = eyes movement (Trochlear) = Jaw -mastication (Trigeminal: sense face & motor jaw) = Eyes - Eye movement (Abducens) = Taster - Taste & facial expression (Facial) = Ears - Ears hearing & balance (Vestibulocochlear) = Licker- tongue taste & swallow (Glossopharyngeal) = ABDMN- Autonomic control thorax & ABDMN (Vagus) = Shoulders -shrug & neck m-nt (Spinal Accessory) = Tongue - Tongue movement (Hypoglossal)
107
Cranial nerves carrying parasympathetic nerve fibers?
CN: 3,7,9,10
108
Cranial nerves name mnemonic: Cranial nerve names:
= “Oh, Oh, Oh, To Touch And Feel A Girl’s Vagina, Such Heaven! 1. Olfactory 2. Optic 3. Oculomotor 4. Trochlear 5. Trigeminal 6. Abducens 7. Facial 8. Vestibulocochlear (or Auditory) 9. Glossopharyngeal 10. Vagus 11. Spinal Accessory 12. Hypoglossal
109
Cushing’s Syndrome (Hyperadrenalism):
= Excess cortisol → moon face, weight gain (upper body), buffalo hump, purple striae. "Cortisol Cushion"
110
De Winter’s T Waves:
V2 V3 most commonly but can happen any lead ST depression at the J-point & upsloping ST-segments w/ tall, symmetrical T- waves in the precordial leads (LMCA or LAD occlusion) “Hyper T w/ STD”
111
decorded position=
flexing forearms outwards
112
decortit position=
flexing forearms inwards
113
Definition of Seizures: Common Causes of Seizures: 2 Main Types of Seizures:
= Temporary alteration in cerebral activity from massive neuronal depolarization = Hypoxia, hypoglycemia, fever, tumors, stress, trauma, idiopathic = Generalized Seizures & Partial Seizures
114
Definition of Unconsciousness / Coma
= PT cannot be aroused even by strong external stimuli
115
Diabetic Ketoacidosis (DKA) - Type 1: Kussmaul’s Respirations:
= Fat metabolism → ketones → metabolic acidosis (pH <7.35) → hyperglycemia (250-500+), Kussmaul respirations, "fruity breath", ABDMN pain = Deep rapid breathing due to metabolic acidosis from excess ketones.
116
Diabetic Ketoacidosis (DKA) is usually seen in patients with which type of diabetes?
Type I Diabetes
117
Diastole: Systole:
= 1st phase, ventricles fills w/ blood, hold 100mLs & pumps 50-70mLs = “squeeze” 2nd phase, period of cycle myocardium is contracting
118
Different Types of H/As
Tension headaches (most common & from stress) Migraines Sinus headaches
119
Diffuse Axonal Injury) Caused by: 3 Classification categories: Nerves can repair selfs b/c schwan cells but never back to 100 b/c scar tissues (make new neurons daily)
= direct blow to the head * Severe acceleration/deceleration = Mild diffuse axonal injury (mild concussion) – Moderate diffuse axonal injury (classic concussion) – Severe diffuse axonal injury (brainstem injury)
120
Low Back Pain) Degenerative Disc Disease:
= Natural breakdown of the intervertebral disc
121
DRG dorsal respiratory group
Keeps VRG in check
122
DRG dorsal respiratory group
Keeps VRG in check
123
expressive aphasia: Receptive aphasia: PT w/ aphasia be mistaken for:
= words will be garbled = words will be clear but unrelated to your questions. = a psych disorder b/c such difficulty speaking
124
Dysarthria: Dysphonia: Aphasia:
= defective speech caused by motor deficits = voice changes caused by vocal cord problems = defective language caused by neurologic damage to the brain
125
Each nerve root has a corresponding area of the skin, called
a dermatome, to which it supplies sensation
126
Ears) Pinna: External auditory canal Glands: Middle & inner ear: Semicircular canals:
= Visible outer portion of the ear = secrete wax (cerumen) for protection = Structures required for hearing = balance/ equilibrium
127
ECG Lead coronary arteries) Anterior view leads are feed by
(LAD) Left Anterior Descending
128
ECG Lead coronary arteries) Inferior view leads are feed by
(RCA) Right Coronary Artery “feR RCA”
129
ECG Lead coronary arteries) Posterior view leads are feed by
(RCA) Right Coronary Artery &/or (LCX)
130
ECG Lead coronary arteries) Right view leads are feed by
(RCA) Right Coronary Artery
131
ECG Lead coronary arteries) Lateral view leads are feed by
(LCX) Left Circumflex
132
Egphony: Orthopneia:
= changed tone w/ E to A test = breathing improves standing & worsens supine
133
Ejection Fraction (EF): <45% usually indicates: <30%:
= Ratio of blood pumped from the ventricle to the amount remaining @ the end of diastole/ %of blood pumped out from ventricle (60-70%) =<45% usually indicates in or going to CHF =<30% in CHF & chronic cardiac crip on oxy
134
Electrical stimulus from the brain is delivered to the diaphragm via the:
=Phrenic nerve
135
EMD
Electrical Mechanical disassociation (same as PEA)
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Tripoding is for Perched lips is for Acrocyanosis: CAPE cyanosis :
= support upper torso becoming tired = anatomical PeeP (3-5) = only peripheral cyanosis = throw a cape over cyanotic torso up
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Emphysema : Chronic bronchitis:
= “pink puffers” skinny = “blue loafers” Big
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Endocrine Chromaffin Cells (Adrenal Medulla):
Release epinephrine & norepinephrine; overactivity leads to hypertension (pheochromocytoma), underactivity reduces stress response.
139
Endocrine Alpha Cells (Pancreas):
Produce glucagon to increase blood glucose; overproduction results in hyperglycemia, underproduction causes hypoglycemia.
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Endocrine Beta Cells (Pancreas):
Secrete insulin to regulate blood glucose; destruction causes diabetes mellitus.
141
Endocrine Cells
Beta Cells (Pancreas), Alpha Cells (Pancreas), Chromaffin Cells (Adrenal Medulla)
142
Types of Diabetes: Endocrine vs Exocrine:
= Influences nearly every cell, organ, & bodily Fn. = Endocrine releases hormones into the bloodstream; exocrine secretes substances through ducts.
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Types of Diabetes: Islets of Langerhans:
= Type 1 (autoimmune, insulin-dependent) & Type 2 (insulin resistance, linked to obesity, may be managed w/ diet & meds) = Alpha Cells (glucagon ↑ blood sugar), Beta Cells (insulin ↓ blood sugar), Delta Cells (somatostatin inhibits glucagon & insulin).
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Endocrine/hormone) Cortisol Epinephrine
= Stress hormone from adrenal cortex; promotes gluconeogenesis & anti-inflammatory effects. = Adrenal medulla hormone; increases HR, cardiac output, & bronchodilation during stress.
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Endocrine/Hormones System) Glucagon: Insulin: Cortisol
: Secreted by alpha cells of pancreas; increases BG by stimulating glycogenolysis & gluconeogenesis. Binds to receptors on liver, adipose tissue, & heart (reg/s CO). = Secreted by beta cells; lowers BG by enhancing cellular uptake & glycogenesis.
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NS Neurotransmitters) Glutamate: GABA:
= Main excitatory neurotransmitter in CNS. = Primary inhibitory neurotransmitter in CNS.
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NS Neurotransmitters) Glutamate: GABA:
= Main excitatory neurotransmitter in CNS. = Primary inhibitory neurotransmitter in CNS.
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Endocrine/Hormones System) Glucagon: Insulin: Cortisol
: Secreted by alpha cells of pancreas; increases BG by stimulating glycogenolysis & gluconeogenesis. Binds to receptors on liver, adipose tissue, & heart (reg/s CO). = Secreted by beta cells; lowers BG by enhancing cellular uptake & glycogenesis.
149
Enzymes) Amylase: Lipase:
= Breaks down carbohydrates (starches) into simpler sugars (e.g., maltose); found in saliva & pancreas. = Hydrolyzes lipids into glycerol & fatty acids; secreted by the pancreas.
150
Epidural Hematoma) what & where: Nearly always the result of: Commonly hand & hand w/:
= Accumulation of blood between the skull and dura mater = blow to the head that produces a linear fracture = hand & hand w/ basilar skull fracture
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Endocrine/hormone) Parathyroid Hormone (PTH): Thyroid Hormones (T3/T4):
= Increases blood Ca+ by stimulating bone resorption & renal reabsorption. = Regulate metabolism, growth, & development.
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ETCO2=
Measurement of the CO2 concentration at the end of expiration (maximum CO2).
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Eupnea: Hyperpnea: Cheyene-Stokes:
= Normal breathing = Deep breathing = Gradual increases & decreases in respirations w/ periods of apnea; caused by increasing ICP & brainstem injury
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Exhalation process: Inhalation process:
= Passive use→ of respiratory muscles’ elastic recoil. = Active use requiring ATP→ of respiratory muscles (diaphragm & intercostals) to increase the chest’s inner diameter.
155
Expressive aphasia: Receptive aphasia:
= words will be garbled &/or expressed = words will be clear but unrelated to your questions (PT w/ receptive aphasia can have such difficulty talking that you could mistakenly suspect a psych disorder)
156
Eye's Vitals) Direct response: Indirect response (consensual response) Accommodation: Extraocular movement: H test: Nystagmus:
=pupils correct size & do they respond to you? = L-pupil respond when light on R-eye (vice versa) = cross eye = Do both eyes look in the same direction? = “Pupil check” is actually for checking iris “colored part” fn = lacking complete fn, depressensent, SSRI usually dont but TCAs can
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Fascicular Block (Hemiblock):
A block of 1 of the 2 fascicles of the left bundle
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Flat percussion sound:
= “Extremely dull” , Soft intensity , High pitched, short duration, located in muscle & atelectasis
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Foreman magnum Fn & relation w/ brain
hole for SC & Brain stem sit right above hole
160
SVR (Systemic Vascular Resistance):
= resistance blood faces in systemic circulation (arteries size)
161
PVR (Pulmonary Vascular Resistance):
= resistance blood faces in pulmonic circulation EX CHF, R ventricle
162
CLs) Temporal Lobe) know: Functions:
= sensory processor = Hearing & auditory processing, memory storage (hippocampus is located here), language comprehension (Wernicke’s area, typically left hemisphere), emotional responses & smell processing.
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CLs) Frontal Lobe) know by: Fn:
= Personality = Motor control (primary motor cortex), problem-solving, decision-making, & planning (executive functions), personality & emotions, speech production (Broca’s area, typically left hemisphere).
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Functional residual capacity (FRC)=
volume of gas that remains in the lungs at the end of normal expiration
165
Functions of paranasal sinuses?
= Act as a buffer system, reduce skull weight, contain 4 pairs: Maxillary (largest), Frontal, Sphenoid, & Ethmoid.
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Functions of the pleura:
= Reduce friction & Maintains ~ 1/3 of neg/ pressure (~10-15mL fluid)
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GABA receptors location
dispersed through CNS on chloride ion channels in the cell membrane.
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GABA receptors job:
1. When combines w/ the receptors the channel “opens” 2. chloride diffuses & B/c is a anion (neg/ ion),makes inside of cell more negative than the outside. 3. Thus hyperpolarizes membrane making more difficult to depolarize 4. Depolarization therefore requires larger stim/ to cause cell to fire
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Gamma-aminobutyric acid (GABA) =
= chief inhibitory neurotransmitter in CNS binds w/ receptors so channel “opens” & Cl influxs prolonging depolarization b/c it makes the inside of the cell more negative than the outside.
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Gamma-aminobutyric acid (GABA): GABA receptors:
= Chief inhibitory neurotransmitter in the CNS. = across CNS on Cl-channels in cell membrane.
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Gamma-aminobutyric acid (GABA)=
Chief inhibitory neurotransmitter in the CNS.
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gas exchange requires what 3 things
= Perfusion, ventilation, diffusion
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GCS:
E4, M5 (orient, confused, words, sounds, none), S6 (obey, local/withdraw, normal flex, abnorm flex decorb, exten/ decer, none)
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Glucagon Function: Insulin Function:
= Released by alpha cells when blood sugar is low → liver breaks down glycogen into glucose → raises blood sugar = Released by beta cells when blood sugar is high → allows glucose into cells via facilitated diffusion → lowers blood sugar.
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gluconeogenesis
Glucagon stimulates liver breakdown of body proteins & fats w/ subsequent chemical conversion to glucose & produces glucose from nonsugar sources
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glycogenolysis
Glucagon stimulates the breakdown of glycogen
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Glycosuria
The presence of glucose in urine, creates the sweet urine that added mellitus to diabetes.
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Gray matter: White matter:
= (cell bodies) sensory processing = mostly comprising communication pathways (axons) motor
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Guillain-Barré syndrome (GBS): Characterized by : Severe stages: Prognosis:
= PNS disorder in which inflammation causes loss of myelin that surrounds neurons. = M-weakness begins @ distal limbs but rapidly advances to involve proximal muscles as well (ascending paralysis) = Mechanical ventilation is often required (use of steroids provides lil/no improvement) = majority recover almost all neurologic Fn on own w/ little medical intervention
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hat part of the spinal cord does the PSNS originate from?
Cranial & Sacral Spine
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Heart Failure: S/S:
= Weakened heart unable to efficiently pump blood from L-ventricle = Dyspnea, Chest pain/pressure, Tachycardia, Pedal edema (swollen ankles), JVD, Pale & moist skin, AMS
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Heart’s 3 tissue layers:
= Endocardium, myocardium, & pericardium.
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Primary neurotransmitter of sympathetic nervous system? Primary neurotransmitter of the parasympathetic nervous system?
= Norepinephrine (NE). = Acetylcholine (ACh).
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Function of the cricoid ring?
= Only 360° cartilage, narrowest point in pediatrics, vs glottis in adults.
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Hering-Breuer reflex=
prevents over expansion of lungs from inhalation> During inspiration, lungs become distended, activating stretch receptors.
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Epidural Hematoma)
= Hx head trauma, Rapid onset of symptoms, LOC, Lucid interval (min-hours), +ICP w/ N/V/AMS, Lapse in unconsciousness, paralysis on contralateral side of head injury, Dilated, fixed pupil on ipsilateral side., Death PTs usually have better outcome b/c acute symptoms H/A, blurry vision, N/V Venous fast bleed
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SC) 1 white matter surround & covered w/ 2 White matter forms what bundles/columns: 3 White matter composed of: 4 Descending SC tracts:
1= surround Gray matter & covered w/ myelinated Nrv-fibers 2= Anterior, Lateral, & Posterior white columns 3= (Axons) Nrv-cell pathways 4= message/effector to end of tract "Brain to Motor)
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Categories of Motor Pathways: Categories of somatosensory Pathways:
= descending = posterior funiculus-medial lemniscal pathway, Anterolateral pathway, Spinocerebellar pathway
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How do the nerves of the PSNS differ from the SNS?
longer Pre & shorter Post Ganglion
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How do the nerves of the SNS differ from the PSNS?
shorter Pre & longer Post ganglions
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How does the endocrine system control the body?
Via hormones.
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How is asthma treated in an emergency?
Bronchodilators (albuterol, ipratropium), steroids (dexamethasone), magnesium sulfate, and possibly epinephrine for severe cases.
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How often can Epi 1:1,000 be delivered to a patient via IM who is in a severe asthma attack?
Every 3-5mins as needed
194
Hyoid bone F: Broken commonly via:
= anchors tongues = hangman's break (Nooses)
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Turbinate F:
creates turbulence; forcing dust particles laterally “filter system” w/ cilia
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What tubes connects to nasopharnx
Eustaschian tubes
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Hyperglycemia Pathophysiology: S/S:
= Lack of insulin → fat metabolism (lipolysis) → ketones & metabolic acidosis → excessive glucose causes kidney diuresis. = Polyuria (frequent urination), Polydipsia (excessive thirst), Polyphagia (excessive hunger).
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Hyperosmolar Hyperglycemia Syndrome (HHS) is usually seen in patients with which type of diabetes?
Type II Diabetes
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Hyperosmolar Hyperglycemic Syndrome (HHS) - Type 2:
= Gradual onset, hyperglycemia (>600), severe dehydration, AMS, no ketones (no acidosis)
200
Hyperresonance percussion sound:
= “Booming” , loud intensity, Low pitched, long duration, located in Hyperinflated-Lung
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Hyperthyroidism (Graves’ Disease):
= Autoimmune overproduction of thyroid hormones (T3/4) stim/ cell metabolism goiter, exophthalmos (bulging eyes)
202
Hyperventilation 2 late severe signs are shown
= Carpoprfal spasm & Trousseau’s sign
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Hyperventilation Syndrome: Respiratory alkalosis Causes: most common etiologies:
= inappropriate increase in RR is beyond metabolic needs = increase in binding of ionized Ca, thus creating a relative hypocalcemia state (troussos sign) = Anxiety and stress
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Hypoglycemia:
= Blood glucose <70 mg/dL → caused by excess insulin, inadequate food intake → can cause seizures, coma, death.
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Hypothyroidism (Myxedema, Myxedema Coma):
= Inadequate thyroid hormone (T3/4) stim/ "hypo slows cells down" = goiter, heart issues, neuropathy, coma.
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Identify the differences between the visceral and parietal pleura
V=has no nerves P= has nerves
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What would cause a left-shift of the Oxygen Dissociation Curve?
increase in the pH of the blood, decrease in the amount of CO2 & Body Temp
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If Oxygen Dissociation Curve would stay shifted too far to the right, what would this cause?
cause the hemoglobin to decrease it's affinity towards oxygen
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Orthostatic hypotension
PT’s BP drops 20 HR+20 when moved from supine to a seated position
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IF RAAS freaks out:
= BP & afterload increases
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Imitators of Infarct:
LVH, LBBB, Ventricular beats, Pericarditis, BER
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In Type I diabetics with Diabetic Ketoacidosis (DKA), what process increases ventilation?
The lack of available insulin forces the cells of the body to convert to lipolysis in order to make cellular energy.
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Increase in arterial CO2 = what drive
hypercarbic drive
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Inferior Vena Cava Filter
Filter inserted via pelvis to prevent Strokes, PEs, MIs
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Pleural space has a pressure between: W/ expiration the chest wall & diaphragm:
= 4 & 8 mmHg atmospheric P
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Diceph/) Insular Lobe) know by: Critical processor Fns: Location:
= Critical processor = Taste perception, emotional responses & self-awareness, visceral functions (EX: heartbeat, breathing). = Deep within the lateral sulcus, beneath the frontal & temporal lobes. (hidden beneath temporal & frontal lobes)
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Intercalated discs: Discs speed Vs standard cell membrane: Syncytium:
= Special tissue bands inserted between myocardial cells that increase the rate(400x) in which AP is spread from cell-cell thus Syncytium = 400x faster than standard cell membrane drom/Inotropy = Group of cardiac cells physiologically function as a unit, “working together in sync” “top in syncytium to bottom”
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Internal respiration: External respiration:
=exchange of gases (O2 and CO2) at the cellular level =exchange of gases (CO2 and O2) in the pulmonary capillaries
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Intracerebral Hemorrhage) located @ & from: Note w/ symptomology: S/S:
= w/in brain tissue w/ Penetrating & blunt injuries = may vary, mimics CVA, Depends on regions & severity = AMS commonly, Thunderclap H/A, Vomiting, 1 dilated pupil, rapid deterioration
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Intracranial Perfusion) Brain perfusion may be disrupted by: Any reduction in cerebral blood flow triggers: If pressure continues to expand: Brain's response to high CO2 & increasing ICP causes:
= increasing ICP, hypotension, = BP rise (autoregulation) for adequate cerebral perfusion = ICP becomes so high, ICP can impead on Fn or SC = hyperventilation and hypertension
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Cardiac) Intrinsic Risk Factors: Extrinsic Risk Factors: Most important extrinsic factor:
= Genetic predisposition; immunocompromised = Work, Home, environment, smoking = smoking cigs
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Isolated Dextrocardia=
(Hearts on right side) Heart is flipped “Right is Left”, so have to mirror leads, AEDs,
223
Isolated Dextrocardia: Abdominal situs Inversus: Situs Inversus Totalis:
= Heart on right side/flipped “Right = Left” so mirror leads, AEDs = Spleen & Liver flipped but H normal = “EVERYTHING WRONG” H right side
224
Katabolism=
uses fat vs glucose for energy (uses 4 ATP vs. 1)
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Kiesselbach area(little area)=
where 4 different arteries connect together→ super vascular
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Eyes cranial nerves: Lost Eye motor control CN:
= 2, 3, 4, 6 = 4 & 6
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AEIOU-TIPS) A: E: I: O: U-: T: I: P: S:
=Alcohol = Epilepsy = Infection = Opiates (most common OD) / Overdose = Uremia (converts amonia so < toxic) =Trauma = Insulin (~ occurs more than Infection) = Poisoning: = Psychosis = Stroke:
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Kussmaul's sign
inhale +inthoracic Pressure pushes & JVD on inhale, Exhale decreases pressure reliefing JVD
229
Side of heart has most myocardium: Epicardium makes what & how: Pericardium holds what, w/ what color & Fn.:
= L side of heart (muscle) = folds over self to make pericardium = holds 25-50mLs straw color fluid to reduce friction, 150mL = heart can squeeze,
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Larynx:
= adams apple, Cricothyroidr sur
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Left Anterior Fascicle (LAF): Pathway of conducting impulses:
= THIN Located in the anterior & superior portion of the left ventricle = Conducts impulses to the anterior and lateral walls of the L-ventricle
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Left Posterior Fascicle (LPF): Pathway of conducting impulses:
= THICK Found in the posterior & inferior portion of the left ventricle = Conducts impulses o the inferior & posterior walls of the L-ventricle
233
Left Ventricular Failure: S/S:
Fluid backs up from the left ventricle to the lungs = Rales, orthopnea, pink frothy sputum, crackles.
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Left Ventricular Failure: S/S:
Fluid backs up from the left ventricle to the lungs = Rales, orthopnea, pink frothy sputum, crackles.
235
Left Ventricular Hypertrophy (LVH) How to Recognize LVH:
= Enlargement & thickening of the L-ventricle = Take the tallest R wave in V5 or V6 + the S wave in V1 = > 35mm –R in aVL > 11mm
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Lens & Function: Iris: Iris function
= Cellular structure behind iris; Convex & transparent allows images to focus onto the retina =Circular contractile muscle; Its pigment produces color of eye =Controls amount of light reaching the retina by controlling pupil size & initiated by Optic N. CN-II (senses light), & Oculomotor N. CNIII (controls size of pupil)
237
Low Back Pain) Sciatica: From: Causes:
= Severe pain that radiates along sciatic nerve = Compression or trauma to the sciatic nerve = Lumbar herniated disc, Degenerative disc disease, Spondylolisthesis, Spinal stenosis
238
Lower Airway Anatomy) Cricoid ring Narrowest point in Aduldts vs Pedis How many alveoli do you have in your lungs? bronchioles streched out would be how far: Cilia fn & triggers what if obstructed:
= only 360 degree cartilage = Cricoid ring in PEDIs vs adults glottis = 300 mil = 15K miles of bronchioles = Cilia moves up if stuck triggers cough reflex
239
Lown-Ganong) definer: Pathway name & path:
= has short PRI interval = Bundle of James connects posterior internodal pathway to bundle of his
240
Cancer pus in between pleura termed:
= (inpinima)
241
Mahaim Syndrome
Accessory connects to Below bundle of his (wide QRS) looks like VTach
242
Main Components of a Neuron
Cell body (soma) w/ nucleus, Dendrites transmit impulses to soma, Axons transmit impulses away from soma
243
Main inhibitory neurotransmitter: Main excitatory neurotransmitter: Neurotransmitter for reward & motivation: Neurotransmitter Which plays a role in stress response: Neurotransmitter for Mood & helps w/ sleep & digestive regulation:
= GABA = Glutamate = Dopamine = Epinephrine = Serotonin
244
Major Blood Supply to Brain
= Carotid system (anterior) & Vertebrobasilar system (posterior) → both join at Circle of Willis
245
Major Endocrine Glands: Diabetes: Pancreas & Diabetes:
= Hypothalamus, pituitary, thyroid, parathyroid, thymus, pancreas, adrenal glands, gonads = Disease where insulin production or response is impaired → abnormal carbohydrate metabolism & increased blood glucose. = Contains both endocrine (hormone-producing) & exocrine (digestive enzyme-producing) tissues.
246
ARDS) Acute Respiratory Distress Syndrome: Emergency Treatment:
= Fluid invades the alveoli Atelectasis, Immune system responds and increases inflammation to area, Major V/Q mismatch! = Remove PT from water ASAP, Primary assessment, if no pulse, begin immediate CPR, IV/IO & ALS airway (ET), Follow ACLS protocols, Protect from heat loss
247
CN with their correct name) CN 4 CN 10 CN 6 CN 9 CN 8 CN 12 CN 11 CN 3 CN 5 CN 7 CN 2 CN 1
Trochlear 4 Vagus 10 Abducens 6 Glossopharyngeal 9 Acoustic (Vestibulocochlear) 8 Hypoglossal 12 Spinal Accessory 11 Oculomotor 3 Trigeminal 5 Facial 7 Optic 2 Olfactory 1
248
Match the Labels
H= Aorta I= Pulmonary Artery J= Left Pulmonary Veins K= Left Atrium L= Bicuspid Valve M= Aortic Valve N= Left Ventricle O= Papillary Muscle
249
Match the Labels
A= SA Node B= AV Node C= Interventricular Septum D= Right Bundle Branch E= Purkinje System F= Purkinje Fibers G= Left Bundle Branch H= Bundle of His I= AV Junction J= Internodal Pathways K= Bachmann's Bundle
250
Match the labels
A= Superior Vena Cava B= Pulmonary Valve C= Right Pulmonary Veins D= Right Atrium E= Tricuspid Valve F= Chordae Tendineae G= Right Ventricle H= Inferior Vena Cava
251
Meninges) Protective membranes that cover the entire CNS: Layers of the meninges:
= Protective membranes the cover the entire CNS = Dura, Arachnoid Mater, & Pia Mater
252
Mesothelial Cells: Pancreatic Acinar Cells:
= Line body cavities (pleura, peritoneum); secrete lubricating fluid. = Secrete digestive enzymes (e.g., amylase, lipase) into the duodenum
253
Methemoglobin= Methemoglobinemia= treat w/:
= Hemoglobin not picking up ( w/ iron in ferric (Fe3+) vs oxy) = changing color from lack of oxygenated hemoglobins = Methylene Blue
254
Migraine Headaches:
Thought to be caused by changes in blood vessel size in the base of the brain Pain is usually described as pounding, throbbing, and pulsating. Often associated with nausea and vomiting and may be preceded by visual changes Most commonly from vascular size change
255
Monro-Kellie Doctrine: in short:
= The pressure-vol/ relationship between ICP, Vol/ of CSF, blood, brain tissue, & CPP = In the fixed space of the cranial cavity, when one increases, the others must decrease
256
Monroe-Kellie doctrine, which states:
Intracranial volume(fixed)=Brain volume(to include any mass or lesion volume) + CSF volume + Blood volume
257
Most Common type of MI
Inferior
258
Most head injury PTs who're in a coma & likely to need endotracheal intubation have a GCS score of:
8 or less
259
Most lethal type of MI
Anterior
260
Most of the cranial cavity is occupied by the:
Cerebrum
261
Mucus F. =
absorb energy, balance, heat dental roots
262
Globit cells produce for function of: Larynx Cilia propels mucus toward: Cigarette smoking major problem excluding cancer:
= Mucus to trap air contaminants, for the cilia = the pharynx to trigger swallow reflex = leads to destruction of the cilia, leaving the cough reflex as the only protective mechanism.
263
Multiple sclerosis (MS): S/S:
= unpredictable CNS disease; autoimmune attack against myelin inflammation of certain nerve cells followed by demyelination, or destruction of the myelin sheath, thus inability properly conduct impulses = include weakness of one or more limbs, sensory loss, paresthesias, and changes in vision. Symptoms can wax and wane over years, and range from mild to severe. Severe cases can be debilitating, rendering patients unable to care for themselves.
264
Muscle tremors, shivering, and loose electrodes can cause deflections on the ECG called:
Artifact
265
Muscular Dystrophy: Dynamics: PSUEDOHYPERTROPHY: Signs & Symptoms:
= Progressive degeneration & necrosis of skeletal M. fibers = Replacement of M. w/ fat & connective tissue = increased size from connective-T. infiltration = Muscle weakness, Contractures, Chronic resp/ infections, weak cough, Cardiomyopathy
266
Myoclonus: can be symptom w/ NS disorders such as: Pathologic myoclonus:
= temporary, involuntary twitching or spasm of muscle or group of muscles (EX: hiccups) = multiple sclerosis, Parkinson’s, or Alzheimer’s = can distort normal movement and limit a person’s ability to eat, walk, and talk
267
narrowest portion of the adult upper airway is the
Glottic opening
268
Nervous system) Afferent neurons Efferent neurons Interneurons
= sensory transmit stimuli from body to CNS. = Motor Transmit signals from CNS to muscles & glands. = Facilitate communication between sensory & motor neurons in the CNS
269
Nervous System) Glial cells
Astrocytes, Oligodendrocytes, Microglia, Schwann Cells:
270
Nervous System) Neurotransmitters
Acetylcholine (ACh), Dopamine, Serotonin, Glutamate, GABA
271
Examples of toxic-metabolic causes?
Anoxia (lack of oxygen) DKA (diabetic ketoacidosis) Hepatic failure (elevated ammonia) Hypercapnia (↑ CO₂) Hypoglycemia Renal failure Thiamine deficiency Toxic exposure (cyanide, organophosphates)
272
Neurogenic Shock) def: Problems: Occurs @ causing:
= SC/Brain Injury disrupts ability to control body autonomic Fns = “pipe” problem, Unable to maintain BP, Severe reduction CO = above T-vertebrae, loss of all SNS innervation, causing widespread BP plummet
273
NEVER LET HEAD INJURY PTs
HYPOXIC & HYPOTENSIVE
274
Nitroglycerin is administered to a patient having chest pain because it:
Dilates the blood vessels which lowers the afterload pressure.
275
Alpha 1 agonist neurotransmitter: Alpha 2:
= NORepi / Noradrenal = inhibits the release of NORepi = acetylcholine post & pre ganglion
276
Parasympathetic uses Neurotransmitters: Muscarinic (5) receptors found:
= acetylcholine post & pre ganglion = M1: CNS, GI, salv glands M2: SA & AV nodes M3: Smooth Muscles
277
NS Neurotransmitters) Acetylcholine (ACh): Dopamine: Serotonin:
= Excitatory in skeletal muscles; inhibitory in cardiac muscle. = Modulates motor control, mood, & reward pathways. = Regulates mood, sleep, & gut motility.
278
Occipital Lobe) know by: all ojos Functions: Visual processing & interpretation, recognizing shapes, colors, & motion
= all ojos = Visual processing & interpretation, recognizing shapes, colors, & motion
279
o.d. (oculus dexter) o.s. (oculus sinister) o.u. (oculus uterque)
= Right eye "Dexter is my right hand man" = Left Eye = Both eyes "U for Unison")
280
Ocular Muscles do what & Innervated by 3CNs: Remember by:
= control eye m-nt by Oculomotor (CN-III), trochlear (CN-IV),& abducens (CN-VI) = OCULAR MUSCLES is 13 letters = CN 3+4+6
281
Ocular Muscles: Innervated by 3 cranial nerves:
= control eye movement = Oculomotor (CN-III), trochlear (CN-IV),& abducens (CN-VI)
282
Only a fraction of carbon dioxide is transported as a gas. It flows into the alveoli due to the gradient that exists between the concentrations of gases
(PCO2 of 45 mmHg in the pulmonary artery versus 40 mmHg in the alveoli).
283
only condition A-Fib has cadence:
Afib w/ 3rd degree In rhythm "Gandalf dead so Atriums & Ventricles doing own thing
284
Osmotic diuresis
When glucose spills into urine, the osmotic pressure, or concentration of particulates, rises inside the kidney tubule to a Lvl > blood Lvl. Water follows glucose into urine to cause a marked water loss termed
285
Oxygen molecules w/o a job become=
free radical hurting brain & cardio molecules
286
Oxygenation 3 needs=
intact airway, adequate vent & respiration
287
Oxyhemoglobin is: Carbaminohemoglobin: Methemoglobin: Deoxyhemoglobin: Carboxyhemoglobin: Sulfhemoglobin: Glycated Hemoglobin (HbA1c):
= oxygen carrying Hemoglobin = carbon dioxide on hemoglobin amino-acid = Hemoglobin not picking up ( w/ iron in ferric (Fe3+) vs oxy) = Hemoglobin not bound to oxygen. = Hemoglobin bound to carbon monoxide (CO). = Hemoglobin irreversibly bound to sulfur. = Hemoglobin bound to glucose for measuring long-term BGL control
288
P Wave Asystole:
P waves ventricles dont pick up b/c 3rd degree HB (type of PEA)
289
R-atrial enlargement: Upside down P wave cause:
= changes P wave “P Pulmonele” b/c ventricle backing up or vasodialation, L-Pump failure P mitria “P wave double humps”, = impulse comes from AV or below atrias
290
Parasinal sinus F: Pairs & Names:
= buffer system, changes relative weight = 4pairs, Max, Frontal, Sphenoid, Ethoniod
291
Parietal Lobe) Know: Function:
= Sensory perception (touch, temperature, pain) = Sensory perception (touch, temp, pain), spatial orientation & awareness of body position, understanding language (Wernicke's area, typically left hemisphere).
292
Parkinson’s: 4 main characteristics:
= chronic & progressive disorder. = 1. "Pill Rolling" Tremor, 2. Rigidity, 3. Bradykinesia (Norm/, spontaneous, & autonomic mnt slowed/lost) 4. Postural instability (Impaired balance & coordination)
293
Anterior portion of the nose Fn: Lateral wall of nasal cavity is marked by The turbinates create turbulence for:
= hair follicles that help trap large dust particles. = 3 bony turbinates. Between each is a passageway, or meatus, that leads to the paranasal sinuses = helping entrapment & removal of any inhaled foreign particles, such as dust.
294
Fossa Ovalis: Patent Foramen Ovale (PFO): Forman Ovale A&P:
= depression in R-Atrium remnant of Foramen Ovale = ASD; hole in atriums septum that didnt close after out of uterus in fetus = b/c fetus fluid in lung/heart & closes w/ 1st breath b/c lungs neg/ pressure
295
Patient's with a long history of emphysema will tend to present with pinkish skin, this is known as:
Polycythemia
296
PE common with: PE history & S/S Saddle embolism PE:
= immobility, planes, childbirths, long bone fracture = Tachypnea & cardia w/ story = emboli usually from pelvis goes to blocking both lungs
297
Pediatric PTs grunt during exhalation if:
= atelectasis is present to create physiological PeeP
298
Percentage of Blood Flow & Glucose Used by Brain
Brain receives 20% of total blood flow & uses 25% of glucose despite being only 2% of body weight
299
Pericarditis PT's will have more pain with:
= laying down & coughing
300
Peripheral Nerves)Visceral "autonomic" Sensory: Visceral "autonomic" Motor:
= Afferent tracts transmit sensations from visceral organs EX: Sensations such as a full bladder or the need to defecate = Efferent fibers exit CNS & branch to supply nerves to the involuntary cardiac muscle & smooth muscle of the viscera (organs) & to the glands.
301
Peripheral Nerves) Somatic Sensory: Somatic Motor:
= Afferent nerves transmit sensations: touch, pressure, pain, temp, & position proprioception = Efferent fibers carry impulses to the skeletal (voluntary) muscles
302
PETCO2=
Partial pressure of end-tidal CO2 in a mixed gas solution
303
Phrenic nerve branches of what nerve types tracts of heart arm pain w/ heart injury bc:
= C3,4, 5 = Sensory & Motor = Cervical plexus tracts w/ phrenic nerve
304
Pneumonia: Bronchial-pneumonia: Lobar pneumonia Interstitial pneumonia: S/S:
= infection usually migrated from somewhere else = Patchy consolidation >1 lobes (L 2 R 3) = infection in 1 lobe only = Diffuse & Bilateral = Fever/chills, orthopnea, yellow/brown sputum, egphony
305
Poliomyelitis (polio) It is characterized by:
= infectious, inflammatory viral disease of CNS that can result in permanent paralysis. = fatigue, H/A, fever, vomiting, stiffness of the neck, & pain to the hands & feet
306
Poliomyelitis: Poliovirus Transmitted via: S/S:
= Infectious disease invades CNS causing permanent paralysis – Destroys neurons in CNS = fecal -oral route = Most people infected don't have S/S (24-100) will have flulike S/S) & 1-100 will have weakness & paralysis
307
Pontine respiratory
Smooths out transition of inhalation & exhalation
308
Pontine respiratory
Smooths out transition of inhalation & exhalation
309
Preload:
= pressure (volume) w/in the ventricles at the end of diastole & Also commonly called the end diastolic volume (frank starlings law)
310
Preload: Afterload: Mean Arterial Pressure (MAP):
= pressure/vol/ w/in ventricles @ end of diastole “End-diastole vol/“ = resistance against which the heart must pump against (increase afterload= increase ventricular workload) = average pressure in arteries during a single cardiac cycle = pressure that drives blood to tissues (ensuring organ perfusion)
311
Presence of Carotid bruit: What is a carotid bruit:
= usually means= atherosclerosis = sound of turbulent blood flow around partial vessel obstruction
312
Primary anterior Pituitary hormones: TP-FLAG T: P: F: L: A: G:
Thyroid stimulating Hormone Prolactin Follicle Stimulating Hormone Luteinizing hormone Adreno-corticotropic Growth hormone
313
Prinzmetal Angina:
= Coronary Spasm causing pain from Stimulants
314
Procainamide & Lidocaine) class
= class 1A&B Na Channel Blockers = Alterative to Amiodarone in cardiac arrest V-Fib/pVT, Stable monomorphic Ventricular TachyC w/ presserved LVF = V-Tach with a pulse, pre-excitation rhythms (WPW) >50% QRS width
315
Cachexia
Profound weight loss (in context of cancer)
316
Propranolol, Labetalol, Metoprolol) class Labetalol Metoprolol
= class 2 Beta Blockers = 2nd line med for SVT after Adenosine, A-fib/flutter w/RVR, Reduce myocardical ischemia in AMI PT's w/elevated HR, Antihypertensive = Hypertension, 2nd line med for A-Fib/A-Flutter w/ RVR, & SVT
317
Pulse Deficit: Pulse Deficit indicates: Pulsus Alternans: Pulsus Alternans indicates:
= difference in HR w/ auscultation & PR w/ palpation. = not all heartbeats make palpable pulse, often A-Fib = Alternation of strong & weak pulses, typically =L-ventricle dysfunc/or H-failure & often chronic condition of the heart.
318
Pupils: Direct response: Indirect response: Accommodation: Ocular motor movement:
= same pupil in light responds = pupil opposite of light responds = eyes cross when finger to nose = eye movement in "H"
319
Febrile seizure: when pyrogen production stops: Fever hard to differentiate from heatstroke; neuro symptoms may present w/ either Treat:
= fever seizure with kid & cool down = Hypothalamic thermostat will reset to normal = for heatstroke if you are unsure which it is * If child history of febrile seizures, treat for fever.
320
Causes of Structural Lesions (AMS)
Brain tumors, degenerative diseases, intracranial hemorrhage, parasites, trauma
321
Causes of Toxic-Metabolic States (AMS)
= Anoxia, DKA, hepatic failure, hypercapnia, hypoglycemia, renal failure, thiamine deficiency, toxins (cyanide, organophosphates)
322
Chronic Alcoholism Effect on Brain
Interferes w/ thiamine absorption & use, leading to Wernicke’s Syndrome or Korsakoff’s Psychosis
323
CSF & Blood Volume in Brain
Arterial Blood: 30 mL Venous Blood: 120 mL CSF: 150 mL Brain Tissue: 1400 mL
324
Lung Compliance: High compliance: Low compliance:
= The lung’s ability to stretch and expand = Easy to inflate,
325
Difference between active & passive phases of breathing?
= Inhalation requires ATP (active); exhalation is passive unless in COPD or other conditions.
326
Does CO2 bind to the same hemoglobin site as oxygen?
= no, it binds to amino acid in the hemoglobin protein chain thus Carminoglobin
327
Examples of structural lesions?
= Brain tumors, degenerative disease, intracranial hemorrhage, parasites, trauma.
328
Function of Choroid Plexus: 3 Major Components of Intracranial Volume Causes of Hydrocephalus: 2 Types of Shunts for Hydrocephalus:
= Produces CSF = 80% brain tissue, 10% blood, 10% CSF = CSF blockage, leading to increased pressure = VP shunt (drains to abdomen), VA shunt (drains to right atrium)
329
Fundamental unit of the nervous system?
Nerve cell (neuron), composed of a cell body (soma), dendrites (transmit impulses to soma), & axons (transmit impulses away from soma).
330
How does the gradient between alveolar & capillary oxygen concentration affect oxygen transfer?
Less oxygen passes into the bloodstream as the gradient decreases.
331
Key features of chronic bronchitis?
Increased goblet cells, excessive mucus production, rhonchi, productive cough, "blue bloaters."
332
Key features of emphysema?
Destruction of alveoli, CO2 retention, dyspnea, barrel chest, finger clubbing, hypertrophic accessory muscles.
333
Most Common Type of Neuron: Main Excitatory Neurotransmitter in CNS: Main Inhibitory Neurotransmitter in CNS:
= Multipolar = Glutamate = GABA
334
Neurotransmitter of Sympathetic Nervous System: Neurotransmitter of Parasympathetic Nervous System
= Norepinephrine / Noradrenal = Acetylcholine
335
Posterior Column Function
Proprioception & fine touch
336
Posterior Column Function
Proprioception & fine touch
337
PT presents w/hx smoking, productive cough for 3 months/year over 2 years, and cyanosis. What is the most likely condition?
Chronic bronchitis.
338
PT presents w/stridor, drooling, difficulty swallowing, and a sudden onset of fever. What is the most likely condition?.
Epiglottitis
339
PT shows severe dyspnea, barrel chest, pursed-lip breathing, & weight loss. What condition does this describe?
Emphysema
340
Pyramidal Tract Function & Location:
= Motor control, sits dorsally, sends signals ventrally
341
Brown-Séquard Syndrome Effect
Medial spinal cord dissection, causing ipsilateral motor loss & contralateral pain/temp loss
342
Hyperkalemia affect of Neuronal Function
K+ retention disrupts normal efflux, affecting neuron excitability
343
Role of the phrenic nerve?
= Stimulates diaphragm, originates from C3, C4, C5.
344
Role of tonsils?
= Lymphatic tissue for immune defense; "kissing tonsils" can indicate tonsillitis.
345
Q: Role of Type II alveolar cells?
Produce surfactant, last cells to develop in utero (issues in premature babies).
346
Spinothalamic Tract Function & Location:
= Pain & temperature, sits ventrally (ipsilateral function)
347
Spinothalamic Tract Function & Location: Pyramidal Tract Function & Location: Posterior Column Function:
= Pain & temperature, sits ventrally (ipsilateral function) = Motor control, sits dorsally, sends signals ventrally = Proprioception & fine touch
348
Wernicke’s Syndrome vs. Korsakoff’s Psychosis
Wernicke’s Syndrome (Reversible): Ataxia, confusion, eye muscle weakness Korsakoff’s Psychosis (Irreversible): Severe memory impairment
349
What are common S/S of a PT experiencing a pulmonary embolism (PE)?
Sudden onset dyspnea, pleuritic chest pain, tachycardia, hypotension, and signs of hypoxia w/o lung sounds changes.
350
Lobes of the brain & their functions Frontal lobe: Parietal lobe: Temporal lobe: Occipital lobe: Cerebellum:
F] Motor Fn, decision-making, speech (Broca’s area) P] Sensory perception, proprioception. T] Hearing, memory, language comprehension (Wernicke’s area) O] Vision processing. C] Coordination, balance.
351
2 main types of seizures?
Generalized seizures & partial (focal) seizures.
352
2 CSF shunts & where do they drain?
VP (Ventriculoperitoneal) shunt → Drains into the abdomen. VA (Ventriculoatrial) shunt → Drains into the right atrium.
353
What condition presents as diminished lung sounds, hyperresonance, tracheal deviation (late sign), and respiratory distress?
Tension pneumothorax.
354
When CO2 increases in cerebrospinal fluid (CSF):
= CO2 combines w/ water to form an acid, lowering pH & increasing hydrogen ion concentration.
355
Acute respiratory distress syndrome (ARDS)?
Severe inflammation and fluid buildup in alveoli, causing non-cardiogenic pulmonary edema and hypoxemia.
356
What is atelectasis?
Partial or complete collapse of alveoli, often due to mucus plugging or lack of surfactant.
357
What is Korsakoff’s psychosis?
= Chronic, irreversible memory disorder caused by severe thiamine deficiency.
358
Fn of cAMP in cardiac physiology?
= Downregulates, decreasing chronotropy (HR) & inotropy (contractility).
359
What is the function of the diaphragm during respiration?
Contracts to increase thoracic cavity volume, decreasing pressure and allowing air inflow.
360
most common cause of stroke?
= Atherosclerotic plaque rupture & hemostasis leading to thrombotic stroke.
361
What is the most common cause of stroke?
= Atherosclerotic plaque rupture & hemostasis leading to thrombotic stroke.
362
What is the spinothalamic tract responsible for?
= Pain & temperature sensation; located on the ventral side, meaning damage causes contralateral deficits.
363
What is Wernicke’s syndrome?
= Acute, reversible encephalopathy w/ ataxia, nystagmus, confusion, unsteady gait.
364
What is Brown-Séquard syndrome
Spinal cord hemisection causing ipsilateral motor loss & contralateral pain/temp loss.
365
What type of information is transmitted by the dorsal roots of the spinal cord
= Sensory input.
366
What type of information is transmitted by the ventral roots of the spinal cord?
Motor output.
367
Where do embolic strokes typically originate from?
= Carotid arteries, heart (A-fib), or large neck vessels.
368
Why is CO2 released from hemoglobin in the lungs?
= the lower concentration of CO2 in the alveoli.
369
Why time intubation with inhalation in awake PTs?
Vocal cords are widest during inhalation to avoid hitting vascular ventricular folds.
370
RAS: Associated with: Drugs that affect RAS
= Reticular Activating System} Hub from info transmission from dissociation made of network of interconnected neurons in brainstem = wakefulness, consciousness, REM sleep. Hypnotic drugs target the RAS to induce sleep
371
1) Not all of the alveoli remain patent during gas exchange thus: 2) This process is referred to as:
= a small % of blood passes through alveoli w/o exchanging oxygen & carbon dioxide = physiologic shunt (affects ~2% of the total blood flow to the lungs)
372
Residual Volume (RV)=
amount of air remaining in the lungs at the end of maximal expiration (~1200mLs)
373
Resonance percussion sound:
= “Hallow” , loud intensity, low pitched, long duration, located in a normal lung
374
Reticular Activating System (RAS) Function
= Maintains wakefulness & consciousness, regulates sleep-wake cycles
375
Role of turbinates?
Create turbulence to filter air using cilia.
376
SC Transection: Thoracic spine: Cervical spine: Lumbar spine:
= Partially or completely cut in SC w/o Potential to send & receive nerve impulses below injury = Incontinence & paraplegia = Partial/complete resp/ paralysis, quadriplegia, incontinence
377
Schram roth test:
finger nails creates diamonds A fig: normal, B fig: clubber
378
sclera: Cornea: Retina:
= white of the eye; Dense avascular structure gives eye shape = Separates anterior chamber fluid from external environment & permits light to enter the lens & reach the retina. = Sensory network of eye transforms light rays into electrical impulses that the optic nerve transmits to the brain.
379
Seizures Types: Generalized Seizures: Categories:
= Generalized Seizures & Partial Seizures = electrical discharge in small area of brain but spreads to involve entire cerebral cortex, causing widespread malfunction. Associated w/ unconsciousness = Grand Mal Seizures (most common(TonicClonic Seizure), Petit Mal Seizures (Absence Seizure), Pseudo Seizures (Hysterical Seizure), Mimic generalized seizures
380
Sensory Located @ Motor Located @
=in the parietal lobes of the cerebrum = in the frontal lobes of the cerebrum.
381
S/S of this type of hemorrhage may take hours, or even days to develop:
Subdural hematoma
382
Sinus Headaches:
Caused by pressure that is the result of fluid accumulation in the sinus cavities (PTs may have cold-like S/S of nasal congestion, cough, fever) Prehospital emergency care is not required Usually bacterial infection & rq antibiotic
383
Situs Inversus Totali
s= “EVERYTHING WRONG” H right side
384
Cilia In the nose move how & for: When mucus & entrapped particles reach posterior of nasopharynx:
= steady posterior flow of mucus at the same time removing any entrapped particles. = they are swallowed and removed from the body via the digestive tract.
385
Cranial nerve types mnemonic: Nerve types:
= "Some Say Marry Money, But My Bitch Says Big Boobs Matter Most." = 1. Olfactory - Sensory 2. Optic - Sensory 3. Oculomotor - Motor 4. Trochlear - Motor 5. Trigeminal - Both 6. Abducens - Motor 7. Facial - Both 8. Vestibulocochlear (or Auditory) - Sensory 9. Glossopharyngeal - Both 10. Vagus - Both 11. Spinal Accessory - Motor 12. Hypoglossal - Motor
386
Speech Located @ Vision Located @ Personality Located @ Balance & coordination Located @
= most commonly L-temporal lobe of cerebrum =in the occipital cortex of the cerebrum = in the frontal lobes of the cerebrum = in the cerebellum.
387
Spina bifida (SB) Long-term effects: The three most common types of SB:
= neural defect from failure of 1 or > of the fetal vertebrae to close properly during pregnancy thus a portion of SC unprotected. >opening can usually be repaired shortly after birth, but the nerve damage is permanent. = physical & mobility impairments, & most some form of learning disability. = 1. Myelomeningocele (most severe full exposure) 2. Meningocele (meninges protrude through spinal opening) 3. Occulta (mildest form 1/> vertebrae malformed & covered by a layer of skin)
388
Spina Bifida: Different Types) 1. Myelomeningocele: 2. Meningocele: 3. Occulta:
= Neural tube defect from the incomplete closing of vertebrae & membranes around SC 1) Spinal cord & meninges protrude 2) Only the meninges protrude 3) 1 or more vertebrae are malformed
389
Spinal Canal) Vertebral Foramen: Articular facets: Back, chest, pelvic muscles provide: kids can hyperflex more vs adults b/c:
= Contains and protects spinal cord = form joint between vertebra (above & below) Held in place by various lig/s = supports. (post&anterioer longitudinal ligament) (Intervertebral disc & body of vertebral) = kids have larger wedges compared to adults
390
Spinal Cord Dorsal vs. Ventral Roots
Dorsal = Sensory Ventral = Motor
391
SC) Pyramidal Tract: Posterior Columnus: Spinothalamic Tract:
= Motor fn. on the same side = Position & vibration sensation on the same side = Pain & temp sensation to opposite side
392
Spinal Cord Syndromes) Anterior Cord Syndrome: Results from: S/S: Commonly seen w/:
= bony frag/s or pressure compressing arteries of anterior SC = severe extension-flexion injury = Loss of motor, sensory, light, & temp/ Fn below injury site = Old & pedis rear end MVC w/ improper head restraint
393
Spinal Nerve Plexuses) def/: Locations: Key myotomes for neurologic evaluation: Dermatomes
= sensory components of spinal nerves innervate specific & discrete surface areas called dermatomes = distributed from the occiput of the head to the heel of the foot and buttocks. = arm extension (C-5), elbow extension (C-7), small finger abduction (T-1), knee extension (L-3), & ankle (plantar) flexion (S-1).
394
Spodick's Sign, or downsloping of the TP segment on an ECG is usually associated with
Pericarditis
395
Stable & symptomatic doesnt always mean
medicate; ex vagal is all that is needed
396
Stable Angina:
= Predictable chest pain w/ exertion, relieved by rest or nitroglycerin.
397
Diaphragm expansion cause: intrapulmonic P. relation w/ atmospheric P.
= increase chest vol/ thus decrease in air pressure inside the chest cavity (intrapulmonary pressure) = decrease to ~1-2 mmHg
398
Stretch receptors in the lung tissue send a signal to the CNS during inhalation that inhibits the stimulation of the phrenic nerve. This safety mechanism is known as the:
Hering-Beuring reflex
399
Stretch receptors are located @:
= visceral pleura, bronchi & bronchioles walls
400
Stridor most likely indicates:
Swelling of the laryngeal tissues
401
Stroke Management:
} Stroke Alert }Establish & Maintain a patent airway (Advanced airway may be required) }Supplemental O2 (if signs of hypoxia are present) }BGL (treat hypoglycemia w/ IV dextrose) }IV (large gauge preferred) & 15 Lead ECG }Protect paralyzed or Motor deficit PTs from hurting themselves (DONT HAVE PT SIT ON DEFICIT) }LSD & tPA (Fibrinolytic) @ hospital
402
Stroke window for tPA Fibrinolytic checklist
= 3Hr tPA– 0.8 mg/kg (max dose 90 mg)
403
5th leading cause of death each year
= STROKE }Cerebral vascular attack / brain attack) Ischemic 87% & Hemorrhagic 13% 2 sub types of ischemic(Embolic or Thrombotic) Injury from plaque rupture & hemostasis most common reason for stroke Thrombotic is moving clot & most common >Risk Factors: Smoking, HTN, Diabetes, A-Fib, Hyperlipidemia. (smoking & HTN biggest causes
404
structures make up your upper airway? Par-, Lar, Nasophar-, Orophar-pharnx
= Par-, Lar, Nasophar-, Orophar-pharnx
405
Subdural Hematoma) what & where: Occurs after or w/: Deadly b/c: Meningies involveved & most common vessel:
= Accumulation of blood beneath dura mater but outside brain = falls or injuries involving strong deceleration forces = Venous bleed slower S/S onset slower High mortality = Dura & arachnoid involved} Most common vessel is the superior sagittal sinus
406
Tension Headaches:
= frontal lobe} Caused by M. contractions in head & neck – Attributed to stress -Pain is usually described as squeezing, dull, or as an ache.
407
The 4 categories of peripheral nerves are:
= Somatic sensory & Motor, Visceral (autonomic) sensory & Motor
408
What would cause a right-shift of the Oxygen Dissociation Curve?
decrease in the pH of the blood, increase in body temperature, increase in the amount of CO
409
The cauda equina, is located: Vertebra C-2 is known as: Vertebra C-1 is known as:
= Below the level of L2 = the Atlas = the axis
410
Direct ARDS causes: Indirect ARDS causes:
= Pneumonia, Gastric Aspiration, Near drowning, Smoke inhalation = Sepsis, Pancreatitis, Trauma/Burns, High altitude, Blood transfusions
411
The cranium's several bones fused together at called
pseudojoints called sutures.
412
Dystonia: Early symptoms of dystonia include:
= group of disorders characterized by M. contractions that cause twisting & repetitive m-nts, abnormal postures, or freezing in middle of action. Such movements are involuntary and sometimes painful. They can affect a single muscle, a group of muscles, or the entire body =deterioration in handwriting, foot cramps, or a tendency of one foot to drag after walking or running. These initial symptoms can be mild and can be noticeable only after prolonged exertion, stress, or fatigue. In many cases, they become more noticeable and widespread over time. In other individuals, there is little or no progression
413
The forced expiratory volume (FEV) Most commonly, FEV1 measures Peak flow measures: Both these measurements are commonly used for:
= vol/ of air exhaled over measured period of time = air vol/ expelled in 1st sec of a forced expiration = max/ rate of airflow during a forced expiration( Ls of air expiration per min) = assessing PTs w/ lung diseases (COPD, asthma)
414
The forced expiratory volume (FEV) Most commonly, FEV1 measures Peak flow measures: Both these measurements are commonly used for:
= vol/ of air exhaled over measured period of time = air vol/ expelled in 1st sec of a forced expiration = max/ rate of airflow during a forced expiration( Ls of air expiration per min) = assessing PTs w/ lung diseases (COPD, asthma)
415
The "F"s of a PE:
Fat, Fucked, Fractured, Flying, Feet
416
The location where pulmonary arteries enter and pulmonary veins exit is called the:
Pulmonary hilum
417
The main respiratory center lies in the
Medulla Oblengata
418
Material that surrounds gray matter in the spinal cord & is made up largely of axons is called: The covering that protects the entire spinal cord and peripheral nerve roots is called the:
= White matter - Spinal meninges
419
The most important factor that determines the ventilation rate of a patient is the amount of:
Arterial pCO2
420
The narrowest portion of the pediatric upper airway is the:
Cricoid ring
421
The phrenic runs runs off the cervical spinal cord from:
C3-5
422
J waves on a 12-lead ECG w/ PT who is not hypothermic is usually associated w/:
(BER) Benign early repolarizarion
423
The sensory components of the spinal nerves that innervate specific and discrete surface areas are called:
Dermatomes
424
The spinal cord ends in the area of: By adulthood, sections of spinal column that've fused are:
= L1/L2 = Coccyx & Sacrum
425
Muscular dystrophy (MD) refers to a Most common form of MD:
= group of genetic diseases characterized by progressive M. weakness & degeneration of skeletal or voluntary M-fibers. = Duchenne; heart & other involuntary M.s affected in some types of MD
426
The term “collateral circulation” refers to:
An alternative path for blood flow in case of blockage
427
Tonsils are: 3 types of tonsils:
= nodules of lymphoid tissue that are located in the posterior pharynx. = pharyngeal/adenoids, palatine & lingual in Oral cavity
428
lobe that controls Fns as N/V reflex, hunger, thirst, & temp:
Hypothalamus
429
admin/ing NGL to PT suspected of having an acute MI has therapeutic effect b/c
1 Increased coronary artery perfusion through vasodilation 2 Decrease in cardiac afterload pressure from peripheral vasodilation
430
Thick, fibrous, inflexible membranes surrounding muscle that help bind muscle groups together are called:
Fascia
431
This color of skin is associated with severe CO poisoning
Cherry Red
432
Thoracic Aortic Aneurysm (TAA) aka : S/S: Ligament & fixation point:
= Bulging of thoracic aorta. DeBakey Tear = “TEARING PAIN INTO BACK”, SOB, hoarseness, dysphagia = Ligamentum arteriosum, fixed between aorta & pulmonary artery.
433
Thoracic Aortic Aneurysm aka: Definers: ECG changes:
= Debakey Tear = Pulse & BP deficit, Acute "Rip/Tearing" pain, Hetero-perfusion = ST Elevation in aVR and Posterior Leads
434
Thyroid Disorders:
= Hyperthyroidism (Graves’ Disease, Thyroid Storm) & Hypothyroidism (Myxedema, Myxedema Coma)
435
Addison’s Disease (Hypoadrenalism):
= Inadequate cortisol & aldosterone production → adrenal crisis if untreated.
436
Thyroid Storm (Thyrotoxic Crisis):
= "Tense Tachy Temp" Life-threatening thyroid hormone surge → extreme tachycardia, hypertension, fever.
437
TIA S/S:
= “Mini Stroke” Blood flow blocked for short time ~ small thromboembolism & body lysation or vasoconstriction = Lasts few mins to several Hrs usually (can last 24Hrs) Resolves completely within 24 hours No evidence of neurological deficits Precurrsor Over 50% has stroke later Can be single on combination of S/S: visual, phonation, slurring
438
Tidal Volume:
= Amount of air moved in & out of lungs in 1 breath (~500 mL’s in a healthy adult)
439
Time interval markings on ECG paper are placed at:
3-second intervals.
440
Tonic Clonic / Grand mal Seizures: May be caused by: Phases: Concerns:
= (most common) Temp/ alt/ in cerebral activity changes electrical activity in the cerebral cortex. = hypoxia, hypoglycemia, fever, tumors, stress, trauma, idiopathic. = Aura, Tonic, Clonic, Hypertonic, Postical = airway is clear} Intercostal-M.s & diaphragm temporarily paralyzed w/ copious amounts of secretions
441
lack of metabolic substrates (oxygen, glucose, or thiamine can produce
diffuse depression of both sides (hemispheres) of the cerebrum, with or without depression within the brainstem.
442
Toxic-metabolic states involve either:
the presence of circulating toxins or metabolites or the lack of metabolic substrates (oxygen, glucose, or thiamine).
443
Majority Hemorrhagic stroke pts have:
>Thunderclap H/A sudden full cranial vault full force “worst H/A of life”
444
Trachea bifurcates @?
Carina
445
Rx of a PT w/ suspected ARDS can include: except:
= Endotracheal intubation, CPAP if still breathtaking on own, Admin of corticosteroids = Administration of Nitroglycerin
446
Trigeminal neuralgia aka:
tic douloureux
447
Two Main Causes of Altered Mental Status (AMS)
Structural Lesions & Toxic-Metabolic States
448
Two Main Types of Ischemic Stroke: Most Common Cause of Stroke: Common Sources of Emboli in Embolic Stroke
= Embolic & Thrombotic = Thrombotic stroke (clot formation due to atherosclerosis or plaque rupture) = Carotid stenosis, AFib, air embolism
449
Type 1 Diabetes:
= No insulin → cells can’t use glucose → fat breakdown increases → excessive ketones → Diabetic Ketoacidosis (DKA).
450
Type 1 Diabetes:
= Autoimmune destruction of beta cells → no insulin production → requires insulin therapy & frequent glucose monitoring.
451
Type 2 Diabetes:
= Insulin resistance → linked to obesity → managed w/ diet, exercise, & meds that increase insulin secretion or receptor sensitivity.
452
Type 2 Diabetes:
Some insulin is present → prevents excess fat breakdown, so ketones don’t build up → instead, these PTs develop HHS (Hyperosmolar Hyperglycemic Syndrome) without acidosis.
453
Unstable Angina:
= Unpredictable, occurs at rest, more severe, precursor to MI.
454
Up-regulation: More receptors causes:
= Med/hormone causes formation of more receptors than normal = increases target tissue’s sensitivity to the particular medication or hormone.
455
Up-regulation: More receptors causes:
= Med/hormone causes formation of more receptors than normal = increases target tissue’s sensitivity to the particular medication or hormone.
456
Upon arrival you find a 21-year-old patient with obvious severe respiratory distress. The patient is very tachypneic and the family tells you the patient has a long history of asthma. Your partner has connected the patient to oxygen and has also hooked up the patient to ETCO2 monitoring. What would you most likely expect to see on this patient's capnogram?
Hypocarbia and an up-sloping of phase 3 of the capnogram waveform
457
Upper Airway 3 responsibilities for?
= Filter, warm, Humidified
458
V/Q Mismatch & Pathos) Causes of V problem: Causes of Q problem:
= Ventilation issues: Obstruction, swelling, or mechanical disruption. Perfusion issues: PE, severe hemorrhage, or shock.
459
Ventilation: Diffusion: Perfusion:
= Air moving into and out of the lungs. = Gas exchange between alveoli and blood. = Blood flow to tissues for oxygen delivery.
460
Prebotzinger VRG: DRG: Pontine resp:
= "SA resp node” in medulla = transmits via phrenic = receives input from chemoreceptors = com/s w/ VRG to smooth out the vent
461
Vocal cords widest at If intubating awake PT remember:
= inhalation = time during inhalation to avoid hitting vascular ventricular folds
462
Vomiting w/ head injury is a frequent result of:
= Increasing intracranial pressure
463
VT vs SVT w/ aberrancy) 3rd Criteria: Josephson’s Sign: Nadir:
= Josephson’s Sign = Notching near the nadir of the S-wave = deepest/most distal point of depression
464
w/ A/V Sequential regain:
atrial kick
465
Cellular asphyxiation : CO2 attaches to hemoglobin via CO2 doesn't bind to
= cells stuck in 1 of the shifts causing death = amino acid chain (carbminoacid = hem sites
466
Wernicke’s Syndrome (Reversible): Korsakoff’s Syndrome (Irreversible):
= Acute weakness, ataxia, confusion, unsteady gait, nystagmus. = Chronic phase w/ severe memory impairment > Give Thiamine before admin/ of Dextrose for hypoglycemia!
467
What are adrenal gland disorders?
Hyperadrenalism (Cushing’s Syndrome). Hypoadrenalism (Addison’s Disease).
468
What are Kussmaul's respirations?
Deep rapid breathing due to metabolic acidosis from excess ketones.
469
What are the 2 subdivisions of the autonomic NS (ANS)?
Sympathetic & Parasympathetic
470
What are the characteristics of Type 1 diabetes?
Requires external insulin, frequent blood sugar monitoring, & sometimes insulin pumps. ## Footnote Without insulin, glucose cannot enter cells, leading to alternative energy pathways.
471
What are the characteristics of Type 2 diabetes?
Insulin resistance, often linked to obesity; can sometimes be reversed w/ lifestyle changes. Treated w/ meds that increase insulin secretion, enhance receptor sensitivity, or decrease glucagon effects.
472
What are the major endocrine glands?
Hypothalamus, pituitary, thyroid, parathyroid, thymus, pancreas, adrenal glands, gonads.
473
What are the signs & symptoms of hyperglycemia?
3 P’s: Polyuria (frequent urination), Polydipsia (excessive thirst), Polyphagia (excessive hunger).
474
What are the two main branches of the nervous system?
Central & Peripheral
475
What are the two subdivisions of the peripheral nervous system (PNS)?
Somatic & Autonomic
476
What are the two types of ischemic stroke?
= Embolic & thrombotic.
477
What are the types of cells in the Islets of Langerhans?
Alpha Cells: Produce glucagon (raises blood sugar). Beta Cells: Produce insulin (lowers blood sugar). Delta Cells: Produce somatostatin (inhibits glucagon & insulin secretion).
478
What are the types of diabetes?
Type 1: Autoimmune destruction of beta cells → requires insulin. Type 2: Insulin resistance, often linked to obesity; can be managed w/ diet, exercise, & meds.
479
What are thyroid disorders?
Hyperthyroidism (Graves' Disease, Thyroid Storm). Hypothyroidism (Myxedema, Myxedema Coma).
480
What best defines Type I Diabetes?
It is usually caused by an autoimmune response in which the body's immune system attacks and kills the beta cells of the pancreas.
481
What blood glucose level identifies as being hyperglycemic?
> 120mg/dL - >140mg/dL
482
What blood glucose level identifies as being hypoglycemic?
< 70mg/dL
483
What causes endocrine disorders?
Endocrine disorders are caused by internal communication problems.
484
What condition involves chronic hypoxia leading to pulmonary hypertension and right heart failure (cor pulmonale)?
COPD, specifically emphysema.
485
What condition is characterized by insufficient cortisol production from the adrenal glands?
Addison's Disease
486
What condition is more prone to barotrauma
ARDS,
487
What condition might a patient with an enlarged neck, weight loss, and bulging eyes have?
Graves' Disease
488
What cranial nerve allows a patient to make facial expressions and close their eyelids?
Cranial Nerve VII
489
What cranial nerve allows a patient to move their eyes laterally?
Cranial Nerve VI
490
What cranial nerve is affected if a patient's tongue deviates to one side?
Cranial Nerve XII
491
What cranial nerve is responsible for hearing and balance?
Cranial Nerve VIII
492
What cranial nerve is responsible for sensation to the face and motor innervation of mastication muscles?
Cranial Nerve V
493
What cranial nerve might be dysfunctional if a patient has difficulty swallowing?
Cranial Nerve IX
494
What do alpha cells of the pancreas secrete?
Glucagon
495
What do alveolar pores do?
Provide "back doors" between alveoli for air distribution, produce surfactant.
496
What do beta cells of the pancreas secrete?
Insulin
497
What do delta cells of the pancreas secrete?
Somatostatin
498
What do the adrenal glands secrete?
The adrenal glands, located on top of the kidneys, secrete catecholamines such as norepinephrine and epinephrine.
499
What does adrenocorticotropic hormone (ACTH) stimulate?
Stimulates release of corticosteroid hormones cortisol and aldosterone. ## Footnote Targets adrenal cortexes.
500
What does Somatostatin do?
Somatostatin is the opposite of GH (Growth Hormone). "Stopper"
501
What does the endocrine system influence?
Nearly every cell, organ, and bodily function.
502
What does the parathyroid hormone cause?
An increase in the blood Ca level.
503
What does the release of calcitonin from the thyroid gland cause?
The blood Ca level to drop "calcitonin cuts Ca"
504
What dysfunction might a patient experience after a viral infection if they lost their sense of smell?
Olfactory CN 1
505
What ECG pattern is associated with a patient having a pulmonary embolism:
S1Q3T3
506
What effects would you see if the sympathetic nervous system (SNS) was to take over?
"Fight or Flight" increase HR & electricity, GI constriction, ect + tropic effects
507
1}Arterial oxygen concentration (CaO2) calculated: 2}SaO2 represent in the CaO2 equation? 3} Hgb represent in the CaO2 equation? 4} 1.34 represent in the CaO2 equation? 5} 0.003 represent in the CaO2 equation? 6} PaO2 represent in the CaO2 equation?
1} 𝐶𝑎𝑂2=(𝑆𝑎𝑂2× 𝐻𝑔𝑏 × 1.34)+ (0.003 × 𝑃𝑎𝑂2) CaO2=(SaO2×Hgb×1.34)+(0.003×PaO2). 2} Hemoglobin-oxygen saturation (%) 3} Amount of hemoglobin present (g/dL) 4} Amount of oxygen bound to 1 gram of hemoglobin at 1 atmosphere of pressure. 5} Oxygen dissolved in plasma (mL/g Hgb) 6} Partial pressure of oxygen dissolved in plasma
508
Enzyme facilitates CO2 & water reaction in RBC: ions formed when carbonic anhydrase combines CO2 & water:
= Carbonic anhydrase = Hydrogen (H+) & bicarbonate (HCO3−).
509
What findings support a diagnosis of Cushing's Disease?
Moon face, Excessive purple stretch marks, Buffalo hump. "Cushings look like a cushion"
510
What findings would substantiate a suspected overdose of levothyroxine? "Thyroid horomone replacement med"
A-Fib w/ RVR, hypotension and seizures.
511
What happens when CSF drainage is blocked?
= (↑ ICP) can cause Hydrocephalus
512
What happens when T-cells attack normal cells?
When T-cells attack normal cells, it can lead to autoimmune diseases.
513
What hormone contributes to salt and fluid balance?
Aldosterone (ADH) ## Footnote Targets kidneys, blood.
514
What hormone decreases blood glucose levels?
Insulin ## Footnote Targets all cells, particularly in liver, muscle, and fat.
515
What hormone does the hypothalamus release to stimulate growth?
Growth hormone-releasing hormone (GHRH) ## Footnote Targets the anterior pituitary.
516
What hormone does the hypothalamus release to stimulate the adrenal cortex?
Corticotropin-releasing hormone (CRH) ## Footnote Targets the anterior pituitary.
517
What hormone increases blood calcium levels?
Parathyroid hormone (PTH) ## Footnote Targets bone, intestine, kidneys.
518
What hormone increases blood glucose levels?
Glucagon ## Footnote Targets all cells, particularly in liver, muscle, and fat.
519
What hormone inhibits growth hormone release?
Somatostatin (GHIH) Targets the anterior pituitary.
520
What hormone inhibits milk production?
Prolactin-inhibiting hormone (PIH) Targets the anterior pituitary.
521
What hormone is released by the posterior pituitary?
Antidiuretic hormone (ADH) & Oxytocin
522
What hormone is released in response to light and affects mood?
Melatonin Exact action unknown; can help determine daily, lunar, and reproductive cycles.
523
What hormone is responsible for uterine contractions?
Oxytocin Released by the posterior pituitary.
524
What hormone prepares the uterus for pregnancy?
Progesterone targets uterus
525
What hormone stimulates cell metabolism?
Thyroxine (T4) targets all cells
526
What hormone stimulates milk production in mammary glands?
Prolactin (PRL) Targets mammary glands.
527
What hormone stimulates milk production?
Prolactin-releasing hormone (PRH) (Targets anterior pituitary)
528
What hormone stimulates reproduction and functional development of T lymphocytes?
Thymosin Targets white blood cells, primarily T lymphocytes.
529
What hormone stimulates the development of secondary sexual characteristics in females?
Estrogen Targets most cells, particularly those of the female reproductive tract.
530
What hormone stimulates the development of secondary sexual characteristics in males?
Testosterone Targets most cells, particularly those of the male reproductive tract.
531
What hormone stimulates the development of sex cells?
Follicle-stimulating hormone (FSH) Targets ovaries or testes.
532
What hormone stimulates the fight-or-flight response?
Epinephrine (adrenaline) Targets muscle, liver, cardiovascular system.
533
What hormone stimulates the release of estrogen and testosterone?
Luteinizing hormone (LH) Targets ovaries or testes.
534
What hormone stimulates the thyroid gland?
Thyrotropin-releasing hormone (TRH) (Targets anterior pituitary)
535
What hormone stimulates the thyroid to release thyroid hormones?
Thyroid-stimulating hormone (TSH)
536
What hormones are produced by the anterior pituitary?
ACTH (Adrenocorticotropic), TSH (Thyroid-Stimulating), GH (Growth Hormone), PRL (Prolactin), LH (Luteinizing), FSH (Follicle-Stimulating).
537
What hormones does the pituitary gland secrete?
The pituitary gland secretes 2 posterior hormones (ADH/Vasopressin and Oxytocin) and 6 anterior hormones (Thyroid, Prolactin, FSH, LH, Adrenocorticotropic hormone, GH).
538
What hormones does the posterior pituitary secrete?
ADH (Antidiuretic Hormone) & Oxytocin.
539
What is a Thyroid Storm?
Severe Hyperthyroidism Crisis ## Footnote S/S: High fever, TachyC, HTN, AMS. Complications/Rx: Life threat: Arrhythmias | Beta-blockers, Cooling, Fluids.
540
What is Addison’s Disease (Hypoadrenalism)?
Inadequate cortisol & aldosterone production. Can lead to adrenal crisis, requiring immediate treatment. "Addison can't stress"
541
Addison’s Disease: S/S: Complications/Rx:
= HypoAdrenalism Insufficiency "Addison can't stress" = Weakness, Wt loss, HypoT, HyperK+, Bronze skin = Life threat: Adrenal Crisis (Shock) | IV Hydrocortisone, Fluids.
542
What is Adrenal Crisis? S/S: Complications/Rx:
=Acute Cortisol Deficiency = Severe HypoT, Shock, AMS. = Life threat: Circulatory Collapse | IV Hydrocortisone, Fluids.
543
What is Cushing’s Syndrome (Hyperadrenalism) Causes:
Excess cortisol → moon face, weight gain (especially upper body), buffalo hump, purple striae. = Exogenous (steroids) or endogenous overproduction.
544
Cushing’s Syndrome: S/S: Complications/Rx:
= hyperadrealism causing Excess Cortisol = Moon face, Buffalo hump, Wt gain, Purple striae. = Minor life threat: HTN | Treat underlying cause.
545
What is Diabetes Insipidus (DI) S/S: Complications/Rx:
ADH Deficiency → Excess Urination =Polyuria, Polydipsia, Dehydration, HyperNa+. =Life threat: HypoV Shock | IV Fluids, DDAVP.
546
What is diabetes?
Disease where the body’s ability to produce or respond to insulin is impaired, leading to abnormal carbohydrate metabolism & increased blood glucose.
547
Diabetic ketoacidosis (DKA) in Type 1 diabetes: Signs: Treatment:
Fat metabolism → ketone production → metabolic acidosis. =Hyperglycemia (250-500+), ketones, Kussmaul respirations (rapid deep breathing, fruity breath), abdominal pain, pH <7.35. = Fluids, insulin, electrolyte management.
548
What is Graves’ Disease?
Hyperthyroidism ## Footnote S/S: Goiter, Exophthalmos, TachyC, Wt loss, Heat intolerance. Complications/Rx: Minor life threat: Irreg/ rhythms or BradyC | O₂ if needed.
549
hemoglobin W/ carbon dioxide attached to it? – hemoglobin w/ carbon monoxide?
= Carbaminohemoglobin = Carboxyhemoglobin
550
What is hyperosmolar hyperglycemic syndrome (HHS) in Type 2 diabetes? Treatment:
Gradual onset, extreme hyperglycemia (>600), severe dehydration, altered mental status, no ketones (no acidosis). Fluids, electrolyte correction, insulin if needed.
551
What is hyperthyroidism (Graves’ Disease)? Symptoms: Thyroid Storm:
Autoimmune overproduction of thyroid hormones. = Goiter, exophthalmos (bulging eyes). = Life-threatening excessive thyroid hormone release → ↑HR, ↑BP, ↑temp.
552
What is hypoglycemia?
Blood sugar <70 mg/dL, must be corrected immediately. ## Footnote Causes: Excess insulin, inadequate food intake. Symptoms: Pale, diaphoretic, tachycardia, AMS, seizures, possible death.
553
What is Hypoglycemia? S/S: Complications/Rx:
Low Blood Sugar (<70) =AMS, Diaphoresis, TachyC, Seizures. = Life threat: Seizures, Coma | Oral Glucose, IV Dextrose.
554
What is hypothyroidism (Myxedema, Myxedema Coma)? Treatment:
Inadequate thyroid hormones, can lead to goiter, heart issues, neuropathy, coma. =Thyroid hormone replacement.
555
what is hypoxic drive
Anaerobic katabolism aka not enough oxy in blood
556
What is Myxedema Coma? S/S: Complications/Rx:
=Severe Hypothyroidism Crisis = HypoT, BradyC, AMS, Hypothermia. = Life threat: Respiratory failure | IV Levothyroxine, Warmth, Fluids.
557
What is Pheochromocytoma: S/S: Complications/Rx:
Adrenal Tumor → Excess Catecholamines =Severe HTN, TachyC, Sweating, HA. =Life threat: HTN Crisis NEVER ADMIN DOP| Alpha-blockers, Surgery.
558
What is SIADH (Syndrome of Inappropriate ADH) S/S: Complications/Rx:
Excess ADH → Fluid Retention =Dilutional HypoNa+, Low urine output, AMS. =Life threat: Seizures | Fluid restriction, Hypertonic saline.
559
What is status asthmaticus?
Severe asthma not responding to initial treatments; respiratory failure imminent.
560
What is the difference between endocrine and exocrine glands?
Exocrine glands have ducts and can deal with enzymes, while endocrine glands are more systemic.
561
Endocrine vs Exocrine glands?
Endocrine glands release hormones into the bloodstream w/o ducts Exocrine glands secrete substances through ducts.
562
What is the function and type of CN I
(Olfactory)Sensory | Smell | Neither sympathetic nor parasympathetic.
563
What is the function and type of CN II
(Optic) Sensory | Vision | Neither sympathetic nor parasympathetic.
564
What is the function and type of CN III
(Oculomotor) Motor | Eye movement, pupil constriction | Parasympathetic.
565
What is the function and type of CN IV
(Trochlear) Motor | Eye movement (superior oblique) | Neither sympathetic nor parasympathetic.
566
What is the function and type of CN IX
(Glossopharyngeal) Both | Taste (posterior 1/3), swallowing | Parasympathetic.
567
What is the function and type of CN V
(Trigeminal) Both | Facial sensation, mastication | Neither sympathetic nor parasympathetic.
568
What is the function and type of CN VI
(Abducens) Motor | Eye movement (lateral rectus) | Neither sympathetic nor parasympathetic.
569
What is the function and type of CN VII
(Facial) Both | Facial expression, taste (anterior 2/3), lacrimation | Parasympathetic.
570
What is the function and type of CN VIII
(Vestibulocochlear) Sensory | Hearing & balance | Neither sympathetic nor parasympathetic.
571
What is the function and type of CN X
(Vagus) Both | Parasympathetic control of heart, lungs, digestion | Parasympathetic.
572
What is the function and type of CN XI
(Accessory) Motor | Shoulder shrug (trapezius, sternocleidomastoid) | Neither sympathetic nor parasympathetic.
573
What is the function and type of CN XII
(Hypoglossal) Motor | Tongue movement | Neither sympathetic nor parasympathetic.
574
ACTH (Adrenocorticotropic Hormone) fn
Stimulates adrenal cortex to release cortisol.
575
ADH (Antidiuretic Hormone) fn
Increases water reabsorption in kidneys → prevents dehydration.
576
Aldosterone fn
Increases Na+ retention & K+ excretion to regulate BP.
577
Calcitonin fn
Calcitonin lowers blood Ca+ Lvls via promotes osteoblast activity & by inhibiting osteoclasts.
578
What is the function of CN III (Oculomotor)?
Motor | Eye movement, pupil constriction | Parasympathetic.
579
What is the function of CN VII (Facial)?
Both | Facial expression, taste (anterior 2/3), lacrimation | Parasympathetic.
580
Epinephrine fn
Increases HR, BP, & metabolism (fight-or-flight response).
581
FSH (Follicle-Stimulating Hormone) fn
Stimulates follicle maturation in females & spermatogenesis in males.
582
GH (Growth Hormone) fn
Stimulates growth, metabolism, & IGF-1 production in liver.
583
Glucagon fn
Raises blood glucose by stimulating glycogen breakdown.
584
Insulin fn
Lowers blood glucose by promoting glucose uptake into cells.
585
LH (Luteinizing Hormone) fn
Stimulates ovulation in females & testosterone production in males.
586
Melatonin fn
Regulates sleep-wake cycle (circadian rhythm).
587
Oxytocin fn
Stimulates uterine contractions & milk ejection.
588
PRL (Prolactin) fn
Stimulates milk production in mammary glands.
589
PTH (Parathyroid Hormone) fn
Increases blood Ca+ by stimulating osteoclasts & kidney reabsorption.
590
Pancreas fn
The pancreas has the majority of endocrine functions and produces pancreatic juice.
591
Pineal gland fn
The pineal gland secretes melatonin, which regulates the circadian cycle.
592
TSH (Thyroid-Stimulating Hormone) fn
Stimulates thyroid gland to release T3 & T4.
593
What is the Glasgow Coma scale score for a patient who is verbal but confused, closes eyes, and localizes with painful stimulus?
12
594
What is the key organ in diabetes?
Pancreas (contains both endocrine & exocrine tissues).
595
What is the longest cranial nerve in the human body?
Vagus CN 10
596
Main excitatory neurotransmitter in the CNS? Main inhibitory neurotransmitter in the CNS?
= Glutamate = GABA (gamma-aminobutyric acid).
597
What is the main pre and post ganglionic neurotransmitter for the SNS?
Epinephrine
598
What is the main pre and post ganglionic neurotransmitter for the PSNS?
Acetylcholine
599
What is the pathophysiology of hyperglycemia?
Insufficient insulin → reliance on fat metabolism (lipolysis) → ATP & CO₂ production → excess glucose causes kidney diuresis.
600
PCO2 gradient between pulmonary artery & alveoli: Normal arterial oxygen concentration (CaO2): Normal oxygen concentration in alveoli Normal pulmonary arterial circulation: CO2 pulmonary capillaries concentration gradient CO2 pulmonary alveoli concentration gradient:
= Pulmonary artery: 45 mmHg, Alveoli: 40 mmHg = 17 to 24 mL/dL. = Alveoli: 104 mmHg = Pulmonary arterial circulation: 40 mmHg = Capillaries: 45 mmHg = Alveoli: 40 mmHg.
601
Growth hormone (GH) fn
Stimulates body growth in childhood; causes switch to fats as energy source. ## Footnote Targets all cells, especially growing cells.
602
What is the proper care for a Type I diabetic patient with altered mental status and malfunctioning glucometer?
Place the patient on oxygen via a NRB at 12-15 lpm, start an IV and administer 25 grams of IV dextrose for the treatment of suspected hypoglycemia.
603
What is the role of hormones in the endocrine system?
Hormones are chemical substances produced by a gland that act as messenger signals.
604
Thymus?
The thymus matures T-cells (4 & 8) and helps detect irregular human and cancer cells.
605
Thyroid often referred to as?
The thyroid is referred to as the 'internal flame.'
606
What might a patient with damage to the posterior pituitary gland experience?
Excrete too much water and become extremely hypovolemic. (ADH)
607
What occurs for cardiogenic shock to be present: Intrinsic: Extrinsic:
= Pump failure; heart can't supply sufficient blood = “Inside” MI, PE, ect = “Outside” Pericardial tamponade, Tension Pneumo/, ect
608
What organ is key in blood glucose level regulation?
Pancreas
609
What part of the spinal cord does the SNS originate from?
Lumbar & Thoracic Spine
610
What reflex stops us from over ventilating ourselves? What receptors are involved?
Hering-Breuer Stretch receptors
611
What should the release of glucagon by the pancreas cause?
An increase in the BGL.
612
What should the release of insulin by the pancreas cause?
A decrease in the blood sugar level.
613
What triggers glucagon release?
Released by alpha cells when blood sugar drops, triggering the liver to break down glycogen into glucose.
614
What triggers insulin release?
Released by beta cells when blood sugar rises, allowing glucose to enter cells via facilitated diffusion.
615
What type of receptors are used by the parasympathetic nervous system?
Nm (nicotinic muscle), Nn (nicotinic neuronal), & Muscarinic = found in heart
616
What type of receptors are used by the sympathetic nervous system?
A1,A2, B1, B2
617
When Ketones Are Made: Liver & Ketones: Ketosis vs. Ketoacidosis:
= If glucose is unavailable (or cannot enter cells), the body burns fat for energy, producing ketones. = The liver converts fatty acids into ketones when glucose is low = Ketosis is a normal metabolic process (low-level ketones), while ketoacidosis is a dangerous condition (high ketones → acidosis).
618
Which coronary artery feeds the anterior wall of the left ventricle?
Left Anterior Descending (LAD)
619
Which coronary artery feeds the inferior wall of the heart?
Right Coronary Artery (RCA)
620
Which coronary artery feeds the left lateral wall of the heart?
Left Circumflex (LCX)
621
Which cranial nerve controls the size of the pupil?
Cranial Nerve III
622
Which cranial nerve is responsible for shrugging shoulders?
Cranial Nerve XI
623
Which cranial nerve transmits visual information from the retina to the brain?
Cranial Nerve II
624
Which gender tends to have more endocrine problems
Females tend to have more
625
Which ion has the greatest influence on muscular contraction:
= Calcium
626
contraindications for the application of CPAP
Pneumothorax, Apnea, Hypotension
627
Peripheral Nervous System (PNS) Parts:
Autonomic Nervous System, Somatic Nervous System, Sympathetic Nervous System
628
Perfusion problems w/ V/Q Ventilation problems w/ V/Q
= Acute, sudden chest pain and dyspnea from a suspected PE, Hypotension from a severe hemorrhage, Hypoperfusion from an anterior wall MI = Trauma PT w/ suspected flail chest, PT w/ exacerbation of their COPD, Hypoxia from a asthma attack
629
Why do premature infants have difficulty breathing?
Type II alveolar cells, which produce surfactant, develop late in utero, causing respiratory distress in preemies.
630
Why does glycosuria cause fluid loss from the body?
increase amount of water that is not reabsorbed by the kidneys bc Water loves to follow sugar
631
Why does hyperkalemia predispose to seizures?
K+ retention reduces repolarization, keeping neurons partially depolarized & closer to firing threshold.
632
WPW) Orthodromic loop; Antidromic loop: Treatmeats:
= Clockwise reentry w/ narrow complex = Counterclockwise reentry w/ wide QRS = procainamide 1a Na blocker, (if no procain) sedate & cardiovert) cardioversion
633
You are called to a local airport terminal for a patient who is complaining of dyspnea. The patient states they just flew back to the United States from Asia, and was feeling fine until they walked off the plane to claim their checked baggage. The patient states the dyspnea was an acute onset, and also complains of some chest discomfort that they describe as "sharp". You would most likely suspect this patient is having a(n):
Pulmonary embolism
634
You are called to the scene of a patient who was outside playing basketball with friends. The patient stated he had a brief coughing spell and now has become increasingly dyspneic over the last twenty minutes. Your physical assessment reveals diminished lung sounds to the patient's right chest, a blood pressure of 138/90, a pulse rate of 110, and a ventilation rate of 26 per minute. You would most likely suspect this patient is experiencing a(n):
Spontaneous pneumo
635
You are treating a patient with severe asthma that initially was tachypneic but now is becoming unresponsive and bradypneic. This patient has not responded to the administration of bronchodilators. What would you most likely expect to see on this patient's capnogram?
The patient's ETCO2 would start to rise to hypercarbic levels
636
You arrive on scene to find a 30-year-old female unconscious on the floor. The patient has a history of hypothyroidism and her husband thinks the patient attempted suicide by ingesting a massive amount of her levothyroxine medication. Which of the following findings would substantiate this?
A-Fib w/ RVR, hypotension and seizures.
637
What? secreted by the ventricles of the heart in response to excessive stretching of the ventricle myocytes
Brain Natriuretic Peptide (BNP)
638
Main Components of a Neuron
Cell body (soma) w/ nucleus, Dendrites transmit impulses to soma, Axons transmit impulses away from soma
639
Major Blood Supply to Brain
= Carotid system (anterior) & Vertebrobasilar system (posterior) → both join at Circle of Willis
640
Myelinated axon
Faster by 30x via saltatory conduction
641
Un-Myelinated axon
Impulses cell to cell