Mechanisms to adjust water Flashcards
What type of transport occurs in the proximal tubule?
Co transport with glucose, amino acids and phosphate
counter transport Na/H
What type of transport occurs in the TAL
Na, K Cl co transport
what type of transport occurs in the early DT
NaCl co transport
what type of transport occurs in the late DT and collecting ducts
luminal Na and K channels
Why is it important to note the TAL luminal fluid has a positive charge
causes reabsorption of Mg and Ca
when can Cl reabsorption take place
always linked with Na resorption
What is the descending limb of henle permeable to? impermeable?
permeable to water
impermeable to Na and Cl
What is the ascending limb permeable to? impermeable
permeable to water
thick transport has active na Cl K pump
Why does chloride transport take a while to reabsorb
because has to go transcellular via Cl Na cotranprt then K Cl co transport into blood
What hormones have their effects on the late DCT and collecting duct
aldosterone and ANP and ADH
What is the driving force for K to secrete
the negative charge in the lumen from Na reabsorption
How does aldosterone increase Na reabsorption in principal cells
incorporate Na channels
incorporate Na/K ATPase
Which part of the medulla has the highest solute concentration
the inner medullary interstitial fluid
the countercurrent multiplier mechanism has integrated function of what 3 components
descending, ascending
vasa recta
collecting ducts
Where does ADH promote urea reabsorption
inner medullary collecting duct
