Mechanisms of Action Flashcards by Kristin Johnston | Brainscape

Q

Marijuana Mechanism of Action

A

Retroactive action
Blocks Ca++ channels in the presynaptic terminal, prevents excitation and release of NT
Endocannabinoids produced on demand in postsynaptic neuron
- Anandamide subtype of endocannabinoid

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Q

Alcohol Mechanism of Action

A

GABA agonist -> inhibiting NT,
Inhibits prefrontal cortex so feels freeing
Opens K+ channels causing cell to become negative (K+ ions flow out)

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Q

Nicotine Mechanism of Action

A

Binds to nACh receptors (in brain and around body)
Opens Na++ channels > excitatory

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Q

Caffeine Mechanism of Action

A

Inhibits adenosine: inhibits inhibitor: stimulates

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