Mechanisms Flashcards
Alkane»_space;> halogenoaklane
Free-radical substitution
Alkene»_space;> (di) halogenoalkane / alkylhydrogensulfate
Electrophilic addition
Halogenoalkane»_space; alcohol/nitrile/amine
Nucleophilic substitution
Halogenoalkane»_space;> alkene
Elimination
Conditions and reagents for nucleophilic substitution to form an alcohol:
Reagents - KOH or NaOH
Conditions - warm and aqueous
Conditions and reagents for nucleophilic substitution to form a nitrile:
Reagent - KCN
Conditions - warm and ethanolic
Conditions and reagents for nucleophilic substitution to form an amine:
Reagents - excess NH3
Conditions - warm and ethanolic
Conditions and reagents for elimination:
Reagents - KOH or NaOH
Conditions - hot and ethanolic
KEY DEFINITION: electrophile
An electron pair acceptor
KEY DEFINITION: nucleophile
An electron pair donor
What is the role of OH- ions in nucleophilic substitution?
Nucleophile (electron pair donor)
What is the role of OH- ions in elimination?
Base