Mechanism of actions Flashcards
1
Q
ACE inhibtors
A
inhibits conversion of Ang-I - to ang ii
2
Q
General anesthetics
A
targets Ligand gated ion channels
GABA gated Cl, Nicotine cholinergic receptor gated Cl, NMDA Ca channels and
K+ channels (hyperpolarisation - inhibit transmission)
3
Q
Barbiturates
A
facilitates and simulate GABA on GABA gated CL channel -unconciousness
4
Q
BZD
A
GABA A gated Cl channel facilitation- unconsciousness
5
Q
Propofol
A
GABA A gated Cl channel facilitation - unconsciousness
6
Q
flourinated anesthetics, barbiturates
A
nicotinic cholinergic cation channel inhibition Analgesia, amnesia,
7
Q
Ketamine, N2O
A
inhibit NMDA type glutamate channel (Ca+)