Mechanism of actions Flashcards

1
Q

ACE inhibtors

A

inhibits conversion of Ang-I - to ang ii

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2
Q

General anesthetics

A

targets Ligand gated ion channels
GABA gated Cl, Nicotine cholinergic receptor gated Cl, NMDA Ca channels and
K+ channels (hyperpolarisation - inhibit transmission)

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3
Q

Barbiturates

A

facilitates and simulate GABA on GABA gated CL channel -unconciousness

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4
Q

BZD

A

GABA A gated Cl channel facilitation- unconsciousness

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5
Q

Propofol

A

GABA A gated Cl channel facilitation - unconsciousness

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6
Q

flourinated anesthetics, barbiturates

A

nicotinic cholinergic cation channel inhibition Analgesia, amnesia,

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7
Q

Ketamine, N2O

A

inhibit NMDA type glutamate channel (Ca+)

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