Mebeverine Capsules

Question 1

In the directions for use section of the PIL, one instruction to the patient is to swallow the capsule whole and not to chew it. Why is this?

Answer 1

If it is chewed the modified release will be broken and therefore the capsule will become instant release which could result in an overdose.

Question 2

Describe ONE benefit to the patient of this type of formulation as opposed to standard capsules?

Answer 2

This formulation means the patient needs to take the medication less frequently as it is a modified release tablet.

Question 3

What is the function of titanium dioxide in the formation and why is it important to the formation?

Answer 3

It is a pigment to make the formation more appetizing.

Question 4

These capsules are made from gelatin. Identify TWO groups of people for which gelatin may be unsuitable?

Answer 4

• vegetarians and vegans

* due to religious reasons (eg Jews can’t eat pork)

Question 5

In general, when making capsules extemporaneously why would you need to add a diluent?

Answer 5

Certain fluids are too viscous to be pumped easily or too dense to flow from one particular point to the other. To ease this restricted movement, diluents are added.

Question 6

Describe TWO methods used to fill capsules extemporaneously.

Answer 6

• Punch- pressing capsule into pile of mixture,

* Capsule machines- use trays to hold capsule