Doublebase Gel

Question 1

Describe 2 advantages of a topical gel such as Doublebase, for dry skin.

Answer 1

• Can be used on macerated skin

* softens, moisturises and protects skin by trapping moisture

Question 2

Which excipient is responsible to making this product into a gel formulation, and describe how this occurs?

Answer 2

• Carbomer, as it is a gelling/thickening agent

* This occurs through carbomer increasing the viscosity and form a gel

Question 3

What is sorbitan laurate and why is it used in this product?

Answer 3

• Sorbitan laurate is non-ionic surfactant which is being used as an emulsifying agent in this product

Question 4

Describe the function of glycerol in the product and its importance to the formulation.

Answer 4

• Glycerol is a humectant in this product which means it reduces the loss of water from the gel which would destabilise the formulation and cause it to dry out

Question 5

When making a semi-solid extemporaneously it is normal to make an excess. Why is this and what amount of excess is normally sufficient?

Answer 5

• 5g because when using an evaporating basin, removing all of the product is not possible

Question 6

When making semi-solds extemporaneously what additional safety label must be added to the dispensed label for this medicine, and why is this important?

Answer 6

• USE THIS MEDICINE ON YOUR SKIN

* Important so the patient does not ingest the medicine by mistake