Cosmocol Sachet

Question 1

Why has this product been formulated as a powder as opposed to a tablet or capsule?

Answer 1

Easier to swallow

Question 2

What is the main function of colloidal anhydrous silica in this product?

Answer 2

Surfactant - used for flocculating, coagulating, dispersing and stabilizing

Question 3

Once reconstituted what are the directions for storage of this product?

Answer 3

Reconstituted CosmoCol Orange Flavour solution can be covered and stored in the fridge (2-8⁰C) and should be used within 24 hours

After 24 hours any unused solution should be discarded

The covering stops any bacteria compromising the integrity of the product and the cold slows down the product’s reaction

Question 4

What additional types of excipients are needed in an oral powder compared to a standard tablet, also please identify these in this formulation?

Answer 4

• Binders (colloidal anhydrous silica)
• Sweeteners (saccharin sodium)
• Flavourings (Orange Flavour)

Question 5

When making powders extemporaneously the method used to mix the powders together is referred to as either the ‘doubling up’ technique or the method of ‘increasing proportions’, describe how to carry out this technique.

Answer 5

Starting with the whole amount of the product with the smallest amount needed and adding roughly the same amount of the other product and mixing them together
Then, adding the same amount as the new mixture and continuing until all the powders are mixed

Question 6

How would you package a powder made extemporaneously?

Answer 6

Wrapped in paper (Usually 10cmx10cm). Fold paper using pattern to make sachet. Put individual powders in box and label