MCQs Flashcards

1
Q

Chylomicrons

A
  1. Formed in the gut
  2. Have Apo E-3, Apo A-1, Apo A-2, B-48, C-2, C-3
  3. Flows through thoracic duct to subclavian veins
  4. Not completely degraded by LPL
  5. Are the largest lipoproteins
  6. Contains more triglycerides
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2
Q

Serum globulins

A
  1. Produced in liver + lymphoid tissue
  2. Transport minerals
  3. Can be separated by salt precipitation
  4. Includes certain acute phase proteins
  5. May show enzymatic activity
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3
Q

Vitamin B12 deficiency is associated with

A
  1. Folate trap
  2. Normochromic enterocytes
  3. Increase in dTMP/UMP ratio
  4. Myelin destabilization
  5. Increased serum methyl malonic acid
  6. Increased serum homocysteine levels
  7. Mean corpuscular volume > 100fL
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4
Q

Vegetables

A
  1. Leafy vegetable proteins are rich in lysine
  2. Spinach is rich in soluble fibers
  3. Leafy vegetables, root vegetables, fruit vegetables, flower vegetables contain high non-nitrogen content
  4. Starchy root vegetables have a high energy value
  5. Dark green leafy vegetables are rich in beta carotenes
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5
Q

Dietary fibers

A
  1. Soluble fibers cause poor mixing of enzymes with substrates
  2. Soluble fibres increase excretion of cholesterol
  3. Reduces colon rectal cancers
  4. Sudden increase of fiber content in diet causes bloating
  5. No absorption
  6. Act as probiotics
  7. Increases insulin sensitivity (not secretion)
  8. Delays gastric emptying
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6
Q

Sri Lankan healthy plate

A

1/2 carbohydrate rich foods
1/3 vegetables and green leaves

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7
Q

Free radicals

A
  1. Reduces (oxidises) the amount of polyunsaturated fatty acids
  2. Are produced in cytosolic redox reactions
  3. Superoxide dismutase is the first line of defense from free radical attack
  4. Oxidises haemoglobin to methaemoglobin
  5. Vitamin A is a prominent antioxidant
  6. Partial reduction of oxygen during ETC produces superoxide radicals
  7. Conversion of superoxide to hydrogen peroxide is catalyzed by superoxide dismutase
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8
Q

Jaundice

A
  1. Jaundice is a condition, not a disease
  2. Seen in hepatitis
  3. Also known as icterus
  4. Occurs when there is a tumor in the head of the pancreas
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9
Q

Marasmus

A
  1. Presents a skin and bone child
  2. Is seen in children who have a loss of all macromolecules, not just inferior quality proteins
  3. No oedema
  4. Leads to wasting not stunting
  5. Increases susceptibility to infections
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10
Q

Buffer systems in blood

A
  1. Bicarbonate buffer
  2. Haemoglobin
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11
Q

Nitric oxide synthase

A
  1. Found in endothelium, immune cells, nerve cells
  2. Has 3 isoforms:
    eNOS
    iNOS
    nNOS
  3. Activity is increased by sheer stress on endothelial cells
  4. Regulated by phosphorylation
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12
Q

Surfactant

A
  1. Surfactant specific protein synthesis is regulated by glucocorticoids
  2. Synthesis by type 2 alveolar cells
  3. Facilitates formation of phospholipid monolayer
  4. Deficient in premature babies
  5. Deficiency can affect newborns
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13
Q

Lactose in milk

A
  1. Major energy source
  2. Lower lactose and fat in colostrum
  3. Higher concentration in foremilk than hindmilk
  4. Lower concentration is found in milk produced for preterm babies
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14
Q

Hematological and biochemical parameters declined during anemia in order

A

Serum ferritin, Serum iron, Haemoglobin

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15
Q

Haem containing proteins

A
  1. Myoglobin
  2. Cytochrome P450
  3. Catalase
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16
Q

Serum albumin

A
  1. Transports calcium ion
  2. Higher concentration in plasma than Globulins in a healthy individual
  3. Albumin transports long chain fatty acids
  4. Can be separated by salt precipitation
  5. Albumin is an acute phase protein
17
Q

Amino acid requirement pattern is dependent on

A
  1. Age
  2. Sex
  3. Physical activity
18
Q

Carbonic anhydrase

A
  1. Important to maintain acid base balance
  2. Is found in gastric mucosa, pancreatic cells, renal tubules
  3. Makes CO2 soluble
  4. Contains zinc
19
Q

Adaptations in the leg muscle of a marathon runner

A
  1. Increased fatty acid utilization
  2. Higher number of mitochondria
  3. Lactate production decreases
  4. Myosin ATPase activity decreases
20
Q

Red blood cells

A
  1. Membrane fragility is increased in hereditary spherocytosis
  2. Oxidative stress is higher than intestinal cells
  3. Glucose entering the cell is insulin independent
  4. 2,3-BPG facilitates the binding of O2
  5. NADPH is not used
21
Q

Vascular endothelium is involved in

A
  1. NO synthesis
  2. Synthesis of Von Willebrand Factor
  3. Converts angiotensin 1 to angiotensin 2
  4. Breaks down triglycerides in lipoproteins
22
Q

Features of hemolytic anemia

A
  1. Increased reticulocytes
  2. Decreased serum haptoglobin level
  3. Elevated urine urobilinogen level
  4. Deep icterus
  5. Gallstone formation
23
Q

Decosahexaenoic acid (DHA)

A
  1. Rich in fish oil
  2. Present in vegan diet (seaweed)
  3. Derivative of alpha linoleic acid
  4. Essential for brain, skin & retina development
  5. Added in milk fortification
24
Q

Rice

A
  1. Does not contain gluten
  2. Polishing increases glycemic index
  3. Contains dietary fibres
25
Q

Separation techniques

A
  1. Electrophoresis - charge + molecular mass (physical properties)
  2. Ultracentrifuge - size + density
  3. Salt precipitation - solubility + charge