MCPHS PA Pharmacology Antidepressants EXAM 1

Question 1

Selective Serotonin Reuptake Inhibitors (SSRIs)

Answer 1

Fluoxetine (Prozac)

Paroxetine (Paxil)

Sertraline (Zoloft)

Fluvoxamine (Luvox)

Citalopram (Celexa)

Escitalopram (Lexapro)

Question 2

Selective Serotonin Reuptake Inhibitors (SSRIs) and 5-HTReceptor Modulators

Answer 2

Vilazodone (Viibryd)

Vortioxetine (Trintellix)

Trazodone

Nefazodone

Mirtazipine

Question 3

Serotonin (5-HT) and Norepinephrine (NE) Reuptake Inhibitors (SNRIs)

Answer 3

Venlafaxine (Effexor)

Desvenlafaxine (Pristiq)

Duloxetine (Cymbalta)

Levomilnacipran (Fetzima)

Buproprion (Wellbutrin)

(not a SNRI Dopa and NE reuptake inhibitor)

Question 4

TCAs

Answer 4

Im/Clom/Des-ipramine

Ami/Nor-tryptyline

Question 5

Other Antidepressants

Answer 5

Selegiline/EMSAM Patch

Ketamine

Question 6

SSRI’s ADRs

Answer 6

ADR-s all except SD gone within a few weeks

5HT4- Diarrhea

5HT3- NV

5HT2- Solmnolence and Sexual Dysfunction

5HT1-Headache

Question 7

SSRI other negative Effects.

Answer 7

Weight gain due to 5-HTc antagonism - Paroxetine

Question 8

Triptans

Answer 8

Sumatriptan

Naratriptan

Razatriptam

Zolmitriptan

Almotriptan

Eletriptan

Frovatriptan